Am J Transplant, Volume 20, Suppl 3 Archives - Page 104 of 223 - ATC Abstracts

2020 American Transplant Congress
Pancreatic Cysts Identified During Evaluation for Kidney Transplant: Selective Application of Endoscopic Ultrasound
S. Merani, E. Edney, S. Singh, S. Westphal, L. Vargas
University of Nebraska Medical Center, Omaha, NE
*Purpose: Transplant recipients have a higher incidence of risk-adjusted malignancy than the general population, likely due to immunosuppression. The evaluation of a potential transplant candidate…
2020 American Transplant Congress
Prevalence and Predictors of Sensory Polyneuropathic Signs and Symptoms in Renal Transplant Recipients
S. Nolte¹, J. Hofman¹, A. Gomes-Neto¹, B. de Greef², J. Elting¹, M. Eisenga¹, M. van Londen¹, S. Bakker¹, I. Nolte¹, C. Faber², J. Sanders¹, D. Touw¹, I. Lesman-Leegte¹, S. Berger¹, G. Drost¹
¹University Medical Center Groningen, Groningen, Netherlands, ²Maastricht University Medical Center, Maastricht, Netherlands
*Purpose: Sensory polyneuropathy is a common finding in renal transplant recipients (RTR). Patients with end stage renal disease are at a high risk to develop…
2020 American Transplant Congress
Urinary CXCL10: From Diagnosis to Prediction of BK Viremia in Kidney Transplantation
C. Tinel¹, A. Vermorel¹, D. Picciotto¹, L. Morin¹, C. Legendre¹, M. Rabant², D. Anglicheau¹
¹Kidney Transplantation, Inserm U1151, Necker Hospital, Paris, France, ²Pathology, Necker Hospital, Paris, France
*Purpose: Urinary CXCL10 (uCXCL10) has proved to be a useful tool for the non-invasive diagnosis of acute rejection in kidney transplant recipients (KTRs). Upon development,…
2020 American Transplant Congress
Novel Flow-Based Assay to Detect Allospecific T Cells in Transplantation Study
N. Tanimine¹, B. E. Burrel², J. Pardo², C. Rickert³, K. M. Lee³, K. Deng³, N. Feeney³, C. Leguern³, J. F. Markmann³
¹Department of Gastroenterological and Transplantation Surgery, Hiroshima University, Hiroshima, Japan, ²Immune Tolerance Network, Bethesda, MD, ³Department of Surgery, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA
*Purpose: Identifying and phenotyping donor-reactive T cells in recipients following transplantation may further the understanding of interactions between the recipient’s immune system and donor antigen.…
2020 American Transplant Congress
Unsupervised Analysis of the Alloimmune Response Using Single-Cell Mass Cytometry
J. Harden, X. Wang, C. Esquivel, O. Martinez, S. Krams
Department of Surgery/Division of Abdominal Transplantation, Stanford Univ School of Med, Stanford, CA
*Purpose: Alloimmune responses in acute rejection are complex, involving multiple interacting cell types. Flow cytometry with biased pairwise gating is the gold standard to phenotype…
2020 American Transplant Congress
Using an Ex Vivo Blood-Free Model of Preservation and Reperfusion to Evaluate the Effects of Subnormothermic Perfusion with Hydrogen Sulfide on DCD Porcine Renal Grafts
S. Juriasingani¹, A. Ruthirakanthan¹, M. Richard-Mohamed², M. Zhang¹, M. Levine¹, E. Sogutdelen¹, M. Mandurah¹, A. Sener¹
¹University of Western Ontario, London, ON, Canada, ²London Health Sciences Centre, London, ON, Canada
*Purpose: The need for donor blood complicates the clinical translation of normothermic and subnormothermic perfusion for preservation and graft function evaluation. As such, hemoglobin-based oxygen…
2020 American Transplant Congress
The Requirement of Thymic Irradiation for Induction of Mixed Chimerism and Renal Allograft Tolerance in Non-Human Primates
T. Hirose¹, H. Sasaki¹, T. Oura¹, D. Ma¹, A. Dehnadi¹, R. B. Colvin², I. Rosales², A. B. Cosimi¹, T. Kawai¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Pathology, Massachusetts General Hospital, Boston, MA
*Purpose: Thymic irradiation (TI) has been required for consistent induction of allograft tolerance through a mixed chimerism approach in both murine and nonhuman primate (NHP)…
2020 American Transplant Congress
Donor-Derived Cell-Free DNA (dd-cfDNA) Levels in Stable Pediatric Kidney Transplant Recipients
M. Waide, J. Carmody, I. G. Restaino
Pediatrics, Eastern Virginia Medical School, Norfolk, VA
*Purpose: Among adult kidney transplant recipients, donor-derived cell-free DNA (dd-cfDNA) has been validated as a highly sensitive biomarker for graft rejection. Unfortunately, few data are…
2020 American Transplant Congress
KDPI-Based Kidney Discard Risk Assessment
S. Mehrotra¹, M. Barah², K. Bui³
¹IEMS Department, MEAS, Northwestern University, Evanston, IL, ²IEMS Department, Northwestern University, Evanston, IL, ³Department of Mathematics, University of California, Irvine, Irvine, CA
*Purpose: Despite the vital need, 3,553 (19%) deceased-donor kidneys were discarded in 2018 in the current US allocation system. The discard rate has remained at…
2020 American Transplant Congress
Impact of Severity of Glomerulosclerosis on Long-Term Outcomes in Deceased Donor Renal Transplant Recipients with Donor Acute Kidney Injury
A. Brar¹, A. Gruessner², D. Adey¹, M. Salifu²
¹University of California, San Francisco, San Francisco, CA, ²SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: With long waitlist times for renal transplantation,there is a need to reduce discard rates of donor kidneys.The purpose of this study is to assess…