ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    The Effect of Ex Vivo Preservation and Regulatory T Cells on the Development of Transplant Arteriosclerosis in a Humanized Mouse Model

    A. Knoefel, T. Siemeni, F. Ius, W. Sommer, J. Salman, I. Tudorache, A. Haverich, C. Falk, G. Warnecke

    MHH, Hannover, Germany

    *Purpose: Lung transplantation is the last remaining option for treatment of end stage lung disease. Explanted lungs can be preserved using ex vivo lung perfusion…
  • 2020 American Transplant Congress

    Cardiac Allograft Tolerance Can be Achieved in Non-Human Primates via Transient Mixed Hematopoietic Chimerism and Erythropoietin Administration

    K. Ahrens1, J. M. O1, W. Sommer2, J. Morrissette1, D. Becerra1, P. M. Patel1, A. Dehnadi1, T. Costa1, I. M. Hanekamp1, J. S. Allan3, P. Cravedi4, P. S. Heeger4, G. Benichou1, J. C. Madsen5

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany, 3Center for Transplantation Sciences, Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, 4Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, 5Center for Transplantation Sciences, Division of Cardiac Surgery, Massachusetts General Hospital, Boston, MA

    *Purpose: In non-human primates (NHPs), a mixed chimerism-based conditioning protocol results in kidney transplant tolerance and combined kidney and heart allograft tolerance. Previous work showed…
  • 2020 American Transplant Congress

    A Video Education Intervention to Improve Kidney Transplant Knowledge and Self-Efficacy in Dialysis Center End Stage Renal Disease (ESRD) Patients

    D. A. DuBay1, T. Morinelli1, Z. Sutton1, M. Chastain1, T. Thompkins Tindal1, Z. Su1, E. Weeda1, P. Mauldin1, M. Casey1, J. Bian1, J. Rodrigue2, P. Baliga1, D. Taber3

    1Medical University of South Carolina`, Charleston, SC, 2Departments of Surgery and Psychiatry, Beth Israel Deaconiess Medical Center, Boston, MA, 3Department of Surgery, Medical University of South Carolina`, Charleston, SC

    *Purpose: Only 34% of incident ESRD patients are referred for transplant (Tx) evaluation within 12 months of initiating dialysis. There is great need for effective…
  • 2020 American Transplant Congress

    The Eplet-Mismatch Landscape in Kidney Patients and Deceased Donors in British Columbia

    J. Tran1, O. Gunther2, J. Lan1, M. Kadatz1, R. Sapir-Pichhadze3, P. A. Keown1

    1University of British Columbia, Vancouver, BC, Canada, 2Gunther Analytics, Vancouver, BC, Canada, 3McGill University, Montreal, QC, Canada

    *Purpose: Minimizing quantitative donor/recipient mismatch at the HLA epitope level may optimize graft outcomes in renal transplantation, but the degree to which optimal matching can…
  • 2020 American Transplant Congress

    Gross Morphological Score for Deceased Donor Kidneys Can Predict Delayed Graft Function in Kidney Transplant Recipients

    M. Mandurah, M. A. Levine, A. Sener, P. Luke

    Department of Kidney Transplantation, London Health Sciences Center, London, ON, Canada

    *Purpose: Both microscopy and kidney donor profile index (KDPI) scoring systems have been used to predict kidney transplant outcomes. Utilizing gross renal morphology, we designed…
  • 2020 American Transplant Congress

    Proportion of Veillonella and the Risk of New-Onset Diabetes Mellitus after Kidney Transplantation

    K. Ji Eun1, H. Kim1, H. Cho2, J. Park3, J. Lee4, D. Kim1, K. Joo1, Y. Kim1, H. Lee1

    1Seoul National University Hospital, Seoul, Korea, Republic of, 2Chungbuk National University Hospital, Cheongju, Korea, Republic of, 3Kangwon National University Hospital, Chuncheon, Korea, Republic of, 4Seoul National University Boramae Hospital, Seoul, Korea, Republic of

    *Purpose: New-onset diabetes transplantation after transplantation (NODAT) is an important metabolic complication after kidney transplantation, although its mechanism is not yet fully elucidated. Recent studies…
  • 2020 American Transplant Congress

    Anti-IL-6 Antibody Clazakizumab in Late Antibody-Mediated Rejection – Molecular Rebound Phenomena Under IL-6 Blockade?

    A. Borski1, S. Haindl2, M. Duerr3, K. Budde3, S. Schranz1, F. A. Eskandary2, K. Doberer2, P. F. Halloran4, E. Chong5, B. Jilma1, G. A. Böhmig2, M. Wahrmann2

    1Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria, 2Department of Medicine III, Medical University of Vienna, Vienna, Austria, 3Charité Universitätsmedizin Berlin, Berlin, Germany, 4University of Alberta, Edmonton, AB, Canada, 5Vitaeris Inc., Vancouver, BC, Canada

    *Purpose: Late antibody-mediated rejection (ABMR) is well established as a major cause of kidney allograft failure. Targeting interleukin-6 (IL-6), a pro-inflammatory cytokine involved in B…
  • 2020 American Transplant Congress

    Multi- National Survey among Nephrologists & Transplant Surgeons about the Suitability and Acceptance of the Marginal Living Kidney Donors with Microscopic Hematuria

    Z. Arabi1, S. Kaysi2, A. Hamad3, M. Bukhari4

    1KAMC, Riyadh, Saudi Arabia, 2CHU Clermont-Ferrand, Orleans, French Guiana, 3The Regional Medical Center, Orangeburg, SC, 4Taif University, Taif, Saudi Arabia

    *Purpose: Potential kidney donors with isolated hematuria are often excluded from donating although there is a wide controversy about the definition and threshold of investigations…
  • 2020 American Transplant Congress

    Non-Self-Advocacy is Associated with Improved Access to Living Donor Kidney Transplantation

    A. C. Kale, A. S. Elston, R. D. Reed, V. Kumar, B. Berry, D. Hendricks, A. Carter, B. A. Shelton, M. N. Mustian, H. Qu, P. A. MacLennan, B. J. Orandi, R. M. Cannon, M. J. Hanaway, J. E. Locke

    University of Alabama at Birmingham Hospital, Birmingham, AL

    *Purpose: Our Living Donor Navigator (LDN) program aims to help potential transplant recipients (PTRs) identify live donors with the help of an advocate. These advocates…
  • 2020 American Transplant Congress

    Geographic Discard Disparities of Liver Allografts

    P. I. Kenny Jr1, A. Rana2, J. Vierling2

    1Medical Student, Baylor College of Medicine, Houston, TX, 2Baylor College of Medicine, Houston, TX

    *Purpose: The aim of this study is to demonstrate the significant geographic disparity in liver allograft discard.*Methods: Using the OPTN Diseased Donor Network database, we…
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