Am J Transplant, Volume 20, Suppl 3 Archives - ATC Abstracts

2020 American Transplant Congress
Poly (ADP-Ribose) Polymerase Inhibitor Treatment Attenuated Renal Ischemia-Reperfusion Injury
H. Jang, K. Lee, J. Jeon, J. Lee, Y. Kim, D. Kim, W. Huh
Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of
*Purpose: Robust intrarenal inflammatory responses following ischemia-reperfusion injury (IRI) induce renal injury in ischemic acute kidney injury (AKI). We hypothesized that poly (ADP-Ribose) polymerase (PARP)…
2020 American Transplant Congress
2-Year Results of a Naturalistic Study of De Novo Extended-Release Tacrolimus Tablets vs. Tacrolimus Immediate-Release Capsules in Kidney Transplant Recipients
J. Hagopian¹, S. January¹, N. Nesselhauf¹, K. Progar¹, T. Horwedel², R. Delos Santos³
¹Barnes-Jewish Hospital, Saint Louis, MO, ²Veloxis Pharmaceuticals, Cary, NC, ³Washington University, Saint Louis, MO
*Purpose: In December 2015, our center instituted a protocol change moving to de novo use of tacrolimus-XR (LCPT). The objective of this extension study is…
2020 American Transplant Congress
Patient-Reported Outcomes in a Prospective Multicenter Trial of Belatacept-Based CNI- and Corticosteroid-Free Immunosuppression Regimens in Kidney Transplantation: A Prospective Analysis Across Two Years
J. M. Rohan¹, J. Leone², E. Woodle³, D. Kaufman⁴, A. Shields⁵, A. Wiseman⁶, A. Matas⁷, P. West-Thielke⁸, E. King⁵, R. Alloway³
¹Pediatrics, Children's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA, ²Tampa General, Tampa, FL, ³University of Cincinnati, Cincinnati, OH, ⁴U Wisconsin, Madison, WI, ⁵U Cincinnati, Cincinnati, OH, ⁶U Colorado, Denver, CO, ⁷U Minnesota, Minneapolis, MN, ⁸UIC, Chicago, IL
*Purpose: Previous trials have not examined 2-year longitudinal differences in patient-reported outcomes (PRO) between belatacept (BELA)- and tacrolimus (TAC)-based therapies in adult kidney transplant (KTx)…
2020 American Transplant Congress
Survival Benefit of Accepting Kidneys from Older Donation after Cardiac Death Donors
S. Yu, J. Long, Y. Yu, M. Bowring, J. Motter, T. Ishaque, D. Segev, J. Garonzik-Wang, A. Massie
Johns Hopkins, Baltimore, MD
*Purpose: Kidneys from older donation after cardiac death (DCD) donors are less likely to be transplanted due to concerns about inferior post-transplant survival. But candidates…
2020 American Transplant Congress
Deceased Donors in Kidney Paired Donation
J. D. Kalbfleisch¹, W. Wang¹, M. A. Rees², A. B. Leichtman³, P. X. Song¹, V. Ashby¹, T. Shearon¹
¹Biostatistics, University of Michigan, Ann Arbor, MI, ²University of Toledo, Toledo, OH, ³University of Michigan, Ann Arbor, MI
*Purpose: A kidney paired donation pool (KPDP) consists of transplant candidates and their incompatible living donors along with nondirected living donors (NDDs). In a match…
2020 American Transplant Congress
Widespread Deregulation of Metabolic Genes in Steatotic Livers Pre- And Post-Transplantation
A. R. Wolen¹, C. Kuscu², C. Kuscu², A. Bajwa², J. Eason², S. Sataphaty³, J. D. Eason¹, D. Maluf¹, V. Mas¹
¹Department of Surgery_ University of Tennessee, James D Eason Transplant Institute, Memphis, TN, ²Department of Surgery, Transplant Research Institute, James D. Eason Transplant Institute, University of Tennessee Health Science Center, Memphis, TN, ³Sandra Atlas Bass Center for Liver Diseases & Transplantation, Northshore University Hospital/Northwell Health, NYC, NY
*Purpose: The escalating obesity crisis is a double-edged sword for the field of liver transplantation; higher rates of fatty liver disease increase both the demand…
2020 American Transplant Congress
Comparative Analysis of Kidney Transplant-Specific versus Hospital-Wide Antibiograms
J. D. Lewis
Medical University of South Carolina, Charleston, SC
*Purpose: Solid organ transplant (SOT) recipients are more likely to develop antimicrobial-resistant infections versus the general population, but few transplant centers have developed SOT-specific antibiograms…
2020 American Transplant Congress
C-Reactive Protein 1-Year Post-Transplant is Associated with Future Development of Coronary Artery Vasculopathy and Rejection in a Pediatric Heart Transplant Cohort
H. J. Tadros, A. H. Bashir, F. J. Fricker, B. A. Pietra, D. Gupta
Congenital Heart Center/Pediatrics, University of Florida, Gainesville, FL
*Purpose: Coronary artery vasculopathy (CAV) is one of the leading causes of mortality beyond 3y post-transplant (OHT). Multiple risk factors are associated with development of…
2020 American Transplant Congress
Molecular Profiles of Injury in Heart Transplant Allograft: Relationship to Rejection, Ejection Fraction, and Survival
P. Halloran¹, J. Reeve², &. the INTERHEART Study Group³
¹University of Alberta, Edmonton, AB, Canada, ²Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ³., ., AB, Canada
*Purpose: In previous studies we used microarray analysis of gene expression to identify rejection in heart transplant endomyocardial biopsies, and found that this also revealed…
2020 American Transplant Congress
Conversion to Belatacept in HIV(+) Renal Transplant Recipients
A. Santeusanio, A. Bhansali, R. Shapiro, G. De Boccardo
Mount Sinai Hospital, New York, NY
*Purpose: HIV(+) renal transplant recipients were excluded from phase III trials of belatacept, and currently there are only scattered case reports.*Methods: This was a single…

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