ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Utilizing Imagestream Technology to Determine Hepatocellular CD38 Localization

    Y. Lee, J. Kim, B. F. Reader, C. Akateh, K. R. Maynard, K. W. Washburn, J. L. Zweier, B. A. Whitson, S. M. Black

    Department of Cardiac Surgery, The Ohio State Univ. Medical Center, Columbus, OH

    *Purpose: CD38 is an ecto-enzyme that modulates intracellular calcium levels by producing potent secondary messengers, which utilize the cellular NAD pool and lead to increased…
  • 2019 American Transplant Congress

    CD56+CD57+ Infiltrate is a Predominant Subset of Infiltrating Natural Killer Cell in Renal Transplant Biopsies with Antibody-Mediated Rejection

    H. Jung1, Y. Wee2, J. Kim2, M. Choi2, J. Choi2, H. Kwon2, J. Jung2, S. Kim3, Y. Cho4, Y. Park4, H. Go4, M. Han5, Y. Kim2, D. Han2, S. Shin2

    1Department of Biomedical Science, Asan Medical Institute of Convergence Science and Technology (AMIST), Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of, 2Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of, 3Department of Convergence Medicine, Asan Institute for life sciences, Asan Medical Center, Seoul, Korea, Republic of, 4Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of, 5Department of Clinical Epidemiology, Asan Medical Center, Seoul, Korea, Republic of

    *Purpose: To verify a subset of intragraft and circulating natural killer cells associated with kidney allograft rejection and fibrosis.*Methods: Thirty-nine clinically indicated transplant biopsies performed…
  • 2019 American Transplant Congress

    Graft Survival of Fourth Time Renal Transplant Recipients Are Similar to Third Time Transplants: A SRTR Database Analysis

    B. Petrun, R. Nygaard, M. Hill, C. Richardson, A. Israni, P. Stahler

    Hennepin County Medical Center, Minneapolis, MN

    *Purpose: The number of candidates for repeat kidney transplant in the United States has steadily increased over the last 30 years. Second and third kidney…
  • 2019 American Transplant Congress

    Transplantation of the Highly Sensitized Renal Transplant Candidate in the Post-KAS Era: Who is Left Out?

    C. Schinstock, B. Smith, A. Bentall, M. Stegall

    Mayo Clinic, Rochester, MN

    *Purpose: Highly sensitized kidney transplant candidates are given high priority under the new kidney allocation system (KAS), but it is unclear if all sensitized candidates…
  • 2019 American Transplant Congress

    Conversion from Tacrolimus Immediate Release to Tacrolimus Extended Release (Envarsus XR®): A Real World Cohort Highlighting Dosing Variability among Patients

    K. D. Belfield1, D. Malhotra2, M. Waleed3, E. A. Cohen1

    1Department of Pharmacy, Yale New Haven Hospital, New Haven, CT, 2Yale University School of Medicine, New Haven, CT, 3University of Connecticut School of Pharmacy, Storrs, CT

    *Purpose: Tacrolimus extended release (TacER) (Envarsus XR®) has become an attractive alternative to tacrolimus immediate release (TacIR) due to its once daily dosing scheme, favorable…
  • 2019 American Transplant Congress

    Delayed Achievement of Therapeutic Tacrolimus Levels with De Novo Extended-Release Tacrolimus Tablets and the Incidence of Rejection in Kidney Transplant Patients

    C. E. Carthon1, J. C. Hagopian1, S. E. January1, A. Gharabagi1, R. Delos Santos2, T. A. Horwedel3

    1Pharmacy, Barnes-Jewish Hospital, Saint Louis, MO, 2Nephrology, Washington University School of Medicine, Saint Louis, MO, 3Veloxis Pharmaceuticals, Inc., Cary, NC

    *Purpose: Early therapeutic tacrolimus levels have been associated with improved outcomes in renal transplant recipients while lower exposure to tacrolimus during the first week of…
  • 2019 American Transplant Congress

    Early Rejection Outcomes with IL-2 vs. ATG Induction among Kidney Transplant Recipients Induction Differences with Early Steroid Withdrawal

    C. Burelli, A. Szczepanik, K. Yadav, E. Sanchez, M. Debroy, V. Humphreville, J. Rabets, A. Padiyar, N. Sarabu, A. Jittirat, A. Palanisamy, K. Chavin

    University Hospitals Cleveland Medical Center, Cleveland, OH

    *Purpose: Early steroid withdrawal in kidney transplant (Ktx) patients is controversial and has demonstrated an increased risk of acute rejection with similar long-term outcomes. Data…
  • 2019 American Transplant Congress

    Pre-Liver Transplant Renal Dysfunction is an Independent Predictor of Post-Liver Transplant Return to the Operating Room

    H. M. Wadei, M. L. Mai, C. Taner, A. P. Keaveny, S. Mao, P. Abader, P. Kroner, K. Croome

    Department of Transplant, Mayo Clinic, Jacksonville, FL

    *Purpose: Pre-liver transplant (LT) renal dysfunction predicts worse outcomes post-LT but the reasons for this are unclear. We aimed at identifying the effect of pre-LT…
  • 2019 American Transplant Congress

    Higher Population Donor Service Areas Are Associated With Lower Meld At Death On Wait List And Higher Meld At Removal For “Too Sick

    Y. Hung, Y. Bababekov, C. Rickert, Y. Hsu, D. Chang, H. Yeh

    Massachusetts General Hospital, Boston, MA

    *Purpose: Plans for distance based allocation in liver transplantation have raised concerns that patients listed in more rural Donor Service Areas (DSAs) will be disadvantaged…
  • 2019 American Transplant Congress

    Comparison of Two Dosing Regimens of Valganciclovir for Cytomegalovirus Prophylaxis in High-Risk Liver Transplant Recipients

    A. L. Bixby, L. Fitzgerald, L. Cotiguala, J. M. Park, D. Kaul, C. Sonnenday, S. Tischer

    Michigan Medicine, Ann Arbor, MI

    *Purpose: Significant controversy surrounds the optimal dose and duration of valganciclovir (VGCV) to prevent CMV in high-risk (D+/R-) liver transplant (LT) recipients. High doses cause…
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