Am J Transplant, Volume 19, Suppl 3 Archives - Page 68 of 214 - ATC Abstracts

2019 American Transplant Congress
Persistent Mixed Chimerism, Immune Reconstitution, and Tolerance in Recipients of HLA Matched Kidney and Hematopoietic Cell Transplants
S. Busque, J. Scandling, R. Lowsky, J. Shizuru, E. Meyer, K. Jensen, A. Shori, R. Hoppe, E. Engleman, T. Pham, S. Strober
Stanford University School of Medicine, Stanford, CA
*Purpose: We evaluated the immune reconstitution of recipients of HLA matched combined kidney and hematopoietic cell transplants after tolerance induction*Methods: Twenty nine recipients of living…
2019 American Transplant Congress
Hepatocyte SIRT1 Modulates ATF4/CHOP and Mitigates Liver Transplant Ischemia-Reperfusion Injury: From Bench-to-Bedside
H. Hirao¹, S. Kageyama¹, K. Kadono¹, K. Nakamura¹, T. Ito¹, K. J. Dery¹, D. Oncel¹, X. Li², B. Ke¹, F. M. Kaldas¹, R. W. Busuttil¹, J. W. Kupiec‐Weglinski¹
¹Surgery, Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA, ²National Institute of Environmental Health Sciences, Research Triangle Park, NC
*Purpose: We and others have reported on benefits of endoplasmic reticulum (ER) stress modulation against hepatic ischemia-reperfusion injury (IRI) in orthotopic liver transplantation (OLT). Although…
2019 American Transplant Congress
Kinetics of Pretransplant DSA, Post-Transplant Histology, and Graft Failure after Kidney Transplantation
A. Senev¹, E. Lerut², V. Van Sandt³, J. Callemeyn¹, M. Coemans¹, B. Sprangers², D. Kuypers², M. Emonds¹, M. Naesens²
¹Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium, ²University Hospitals Leuven, Leuven, Belgium, ³Histocompatibility and Immunogenetics Laboratory, Belgian Red Cross-Flanders, Mechelen, Belgium
*Purpose: The association between the kinetics of pretransplant DSA levels and outcome after kidney transplantation is currently not well known. In this large cohort study…
2019 American Transplant Congress
Have Graft Outcomes Improved for Pediatric Transplant Recipients Since the Implementation the Kidney Allocation System
C. S. Bell¹, S. Hebert², A. De Golovine³, R. Swinford¹
¹Division of Pediatric Nephrology & Hypertension, McGovern Medical School at UTHealth - Houston, Houston, TX, ²Division of Nephrology, Department of Internal Medicine, Houston Methodist Hospital, Houston, TX, ³Renal Diseases &Hypertension, McGovern Medical School at UTHealth - Houston, Houston, TX
*Purpose: The new kidney allocation system (KAS) that utilizes a Kidney Donor Profile Index (KDPI) in matching transplant recipients to donors was implemented in December…
2019 American Transplant Congress
Outcomes of Liver Transplantation for Mixed Hepatocellular-Cholangiocarcioma
M. Najjar¹, K. Bruestle¹, P. Jiang¹, S. Robbins-Juarez¹, R. Hwang¹, A. Mathur¹, E. C. Verna¹, A. Griesemer¹, B. Samstein¹, T. Kato¹, Y. M. Saenger¹, K. J. Halazun², J. C. Emond¹
¹Columbia University Medical Center, New York, NY, ²Weill Cornell Medicine, New York, NY
*Purpose: Mixed hepatocholangiocarcinomas (HCC-CCA) are rare tumors with both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) differentiations. They are usually associated with a worse prognosis than…
2019 American Transplant Congress
Physiochemical Hla Properties Identify Low Immunogenic Donor/recipient Pairs Predicting Long-term Kidney Graft Survivals
D. Bekbolsynov¹, B. Mierzejewska², C. Ho¹, M. Rees², S. Stepkowski²
¹Gift of Life Michigan, Ann Arbor, MI, ²University of Toledo, Toledo, OH
*Purpose: Although it is well-recognized that HLA matching improves the long-term kidney graft survival, less than 10% of transplants are currently HLA matched. We measured…
2019 American Transplant Congress
The Risk of Systematic Error in Liver Transplant Opioid Research
J. N. Fleming, N. A. Pilch, S. Ball, P. K. Baliga, D. DuBay, D. J. Taber
Medical University of South Carolina, Charleston, SC
*Purpose: Opioid use before and after liver transplant is strongly associated with morbidity and mortality; yet data assessing opioid utilization has centered on sources with…
2019 American Transplant Congress
Circulating Donor Specific Antibody and Biopsy C4d Positivity in Pancreas Rejection Increase the Probability of Earlier Return to Insulin after Rejection
S. M. Riad¹, S. Jackson², E. B. Finger³, R. Kandaswamy³
¹Medicine, University of Minnesota, Minneapolis, MN, ²Complex Care Analytics, Fairview Health Services, Minneapolis, MN, ³Surgery, University of Minnesota, Minneapolis, MN
*Purpose: Outcome data following rejection in pancreas recipients are sparse. We sought to study the influence of C4d positivity and the presence of circulating DSA…
2019 American Transplant Congress
Measuring and Monitoring Disparities in Access to Kidney Transplantation Associated with Being Listed for a Multi-Organ Transplant (MOT)
D. E. Stewart, C. A. Custer, A. M. Robinson, A. R. Wilk
UNOS, Richmond, VA
*Purpose: In 2018, the OPTN published a new methodology for measuring and monitoring disparities in access to deceased donor kidney (KI) transplantation (Tx) among kidney-alone…
2019 American Transplant Congress
The Impact of Sleeve Gastrectomy Following Liver Transplant in Patients with Non-Alcoholic Steatosis: A Five-Year Experience
M. C. Morris¹, A. D. Jung¹, Y. Kim¹, V. K. Dhar¹, S. Shah¹, D. Schauer², E. Smith², T. Diwan¹
¹Surgery, University of Cincinnati, Cincinnati, OH, ²Medicine, University of Cincinnati, Cincinnati, OH
*Purpose: Non-alcoholic steatohepatitis (NASH) cirrhosis is an increasingly common indication for liver transplantation (LT) in the United States and obese patients continue to be at…