Am J Transplant, Volume 19, Suppl 3 Archives - Page 67 of 214 - ATC Abstracts

2019 American Transplant Congress
Regional Differences in Transplantation for Expected Post-Transplant Survival Top 20% Candidates
S. Husain, K. King, D. Tsapepas, G. Dube, D. Cohen, L. E. Ratner, S. Mohan
Columbia University Medical Center, New York, NY
*Purpose: The Kidney Allocation System (KAS) introduced the Expected Post-Transplant Survival (EPTS) score for deceased donor kidney (DDK) candidates to improve organ-recipient longevity matching. Candidates…
2019 American Transplant Congress
The Impact of Portal Flow after Reperfusion on Graft Outcomes after Deceased Donor Liver Transplantation
H. Matsushima, K. Sasaki, M. Fujiki, T. Diago Uso, B. Eghtesad, F. Aucejo, C. Kwon, C. Miller, C. Quintini, K. Hashimoto
General Surgery, Digestive Disease & Surgery Institute, Cleveland Clinic, Cleveland Clinic, Cleveland, OH
*Purpose: The impacts of intraoperative portal flow (PF) on graft outcomes after living donor liver transplantation have been studied well, however, its impact on graft…
2019 American Transplant Congress
“Getting Life Back” – Kidney Transplantation in the Elderly Patient
V. Tsarpali¹, K. Lønning², K. Midtvedt², T. Bernklev³, N. von der Lippe⁴, M. H. Andersen², K. Heldal¹
¹Clinic of Internal Medicine, Telemark Hospital Trust, Skien, Norway, ²Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway, ³Vestfold Hospital Trust, Tønsberg, Norway, ⁴Oslo University Hospital, Oslo, Norway
*Purpose: The number of elderly patients developing end stage renal disease (ESRD) who are eligible for kidney transplantation (KTx) is increasing, but their transplant rate…
2019 American Transplant Congress
CyTOF and RNAseq Analyses Unravel Early Phenotypic and Transcriptional Changes in Antibody-Secreting and Memory B Cells >1 Year Prior to Antibody-Mediated Rejection
C. Fischman¹, M. Fribourg¹, J. Ansari², L. Gallon², F. Ginevri³, P. Comoli⁴, M. Cioni³, A. Nocera³, M. Bruschi³, C. Cantarelli¹, L. Perin⁵, P. Cravedi¹
¹Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, ²Department of Medicine, Northwestern University, Chicago, IL, ³Department of Medicine, IRCCS Istituto G. Gaslini, Genoa, Italy, ⁴Department of Medicine, IRCCS San Matteo Hospital, Pavia, Italy, ⁵Department of Urology, Children's Hospital Los Angeles, Los Angeles, CA
*Purpose: While the negative impact of anti-HLA donor specific antibodies (DSA) on graft outcomes has been extensively investigated, little is known about early changes in…
2019 American Transplant Congress
Histone Deacetylase-2 Knockout in Renal Tubular Cells is Protective in Renal Ischemia-Reperfusion Injury
P. T. Hernandez¹, S. J. Concors¹, L. Krumeich¹, D. D. Aufhauser¹, Z. Wang¹, D. D. Murken¹, G. Ge¹, W. Hancock², M. Levine³
¹General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, ²Pathology, Children's Hospital of Philadelphia, Philadelphia, PA, ³Transplant Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA
*Purpose: Ischemia-reperfusion injury (IRI) is a major source of morbidity in renal transplantation and is without targeted therapy. In renal transplantation, IRI contributes to poorer…
2019 American Transplant Congress
TDCA/Valine Reverse Obesity and Ameliorate Alloimmune Responses through a Decreased Hypothalamic Expression of MCH
A. ElKhal¹, M. Markus Quante¹, T. Heinbokel¹, Y. Nian¹, K. Minami¹, R. Maenosono¹, J. Iske¹, B. Desai², A. Banks², E. Maratos-Flier², A. Elkhal¹, S. G. Tullius¹
¹Brigham and Women's Hospital, Boston, AL, ²Beth Israel Deaconess Medical Center, Boston, AL
*Purpose: Obesity is associated with low grade inflammation and bariatric surgery is the only effective treatment in reducing excess weight both pre- and post-transplant.*Methods: Here,…
2019 American Transplant Congress
The Evolving Clinical Presentation of Acute Rejection in Face Transplantation
V. Haug, B. Kollar, D. Obed, H. Kiwanuka, M. Turk, L. Wo, S. Tasigiorgos, M. Kueckelhaus, L. Riella, B. Pomahac
Plastic and Reconstructive Surgery, Brigham and Women's Hospital, Boston, MA
*Purpose: Clinical signs such as erythema or edema are traditionally helpful to diagnose Acute rejection (AR) in face transplantation (FT) in the early follow-up. The…
2019 American Transplant Congress
Cardiovascular Mortality in Transplant Patients; A Population-Based Cohort Study 1988-2013 in Australia and New Zealand
M. Wyld¹, N. De La Mata², P. Masson³, E. O'Lone², A. Webster²
¹Renal Department, Royal Prince Alfred Hospital, Camperdown, Australia, ²School of Public Health, University of Sydney, Sydney, Australia, ³Renal Department, Royal Free London NHS Foundation Trust, London, United Kingdom
*Purpose: Transplant recipients experience excess cardiovascular morbidity and mortality. We compared cardiovascular death rates in kidney transplant recipients to the general population and identified risk…
2019 American Transplant Congress
Expanding the Donor Pool with Extended Criteria DCD Livers
P. Mihaylov¹, B. Ekser², R. Mangus², J. Fridell², D. Soma², C. Kubal²
¹Indiana Univ School of Medicine, Pavia Univ School of Medicine, Indianapolis, IN, ²Indiana Univ School of Medicine, Indianapolis, IN
*Purpose: Utilization of extended criteria donation after circulatory death (ECD DCD) livers has remained cautious due to potentially worse outcomes because of higher rates of…
2019 American Transplant Congress
High Numbers of Differentiated CD8⁺CD28^– T Cells Are Associated with a Substantially Lowered Risk for Late Rejection and Graft Loss after Kidney Transplantation
M. G. Betjes, A. Langerak, M. Klepper, N. Litjens
Nephrology & Transplantation, Erasmus MC, Rotterdam, Netherlands
*Purpose: Recipients of a kidney transplant have a prematurely aged T-cell system. This is reflected in lowered thymic output, reduced telomere length and more highly…