ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    The Dry Weight Revealed!, What Transplanted Kidneys Teach Us about the (Dry Weight).

    M. Hamid1, S. Oyewolle-Eletu2, G. Gudleski2, K. Speta3, J. Kumar1, S. Chang1

    1Nephrology-Transplant, State University of New York at Buffalo (SUNY) Buffalo, Buffalo, NY, 2Jacob's School of Medicine, State University of New York at Buffalo (SUNY) Buffalo, Buffalo, NY, 3Nephrology-Transplant, Erie County Medical Center, Buffalo, NY

    *Purpose: Volume overload in patients with ESRD/CKD V patients is associated with worse operative outcomes and potentially higher rate of delayed graft function, in addition…
  • 2019 American Transplant Congress

    Absence of Antibodies in Human Neonates and Infants to Gtko/cmahko/β4galnt2ko (Triple Gene Knockout) Pig Cells: Relevance to Cardiac Xenotransplantation for Complex Congenital Heart Disease

    H. Hara1, Q. Li1, C. A. Banks1, T. Yamamoto1, D. Ayares2, D. C. Cleveland1, D. K. Cooper1

    1Surgery, University of Alabama at Birmingham, Birmingham, AL, 2Revivicor Inc., Blacksburg, VA

    *Purpose: Heart transplantation (Tx) in neonates is associated with the best results of any organ Tx, but the lack of deceased human donor hearts in…
  • 2019 American Transplant Congress

    Pre-emptive Ivig For Dsa Positive Living Donor Kidney Transplant Recipients

    B. Abdalla1, D. Kellner2, A. Diaz2, Y. Zheng3, E. Reed4, Q. J. Zhang4

    1Medicine, Division of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA, 2David Geffen School of Medicine at UCLA, Los Angeles, CA, 3UCLA Immunogenetics Center, Los Angeles, CA, 4Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA

    *Purpose: Intravenous immunoglobulin (IVIG) is used in desensitization regimens to modulate anti-human leukocyte antigen (HLA) donor-specific antibody (DSA) to facilitate transplantation of sensitized patients, however,…
  • 2019 American Transplant Congress

    Policy Changes in Liver Graft Allocation for Hepatocellular Carcinoma in the USA: Improved Survival for African American Recipients

    M. Molinari1, D. Jorgensen1, A. Tevar1, C. Hughes1, A. Humar1, N. Jonassaint2

    1Surgery, University of Pittsburgh Medical Centre, Pittsburgh, PA, 2Medicine, University of Pittsburgh Medical Centre, Pittsburgh, PA

    *Purpose: To evaluate the effect of policy changes in liver graft allocation for hepatocellular carcinoma (HCC) on the overall survival of patients of different ethnicities…
  • 2019 American Transplant Congress

    Karnofsky Performance Score as a Predictor of Acute Cellular Rejection Post Liver Transplantation

    N. Kapila1, K. Al Khalloufi2, F. Salomon3, K. Kapila4, A. Gupta3, X. B. Zervos2

    1Gastroenterology and Hepatology, Cleveland Clinic Florida, Weston, FL, 2Transplant, Cleveland Clinic Florida, Weston, FL, 3Internal Medicine, Cleveland Clinic Florida, Weston, FL, 4Internal Medicine, University of Miami/JFK Medical Center, Atlantis, FL

    *Purpose: The incidence of acute cellular rejection (ACR) following liver transplantation (LT) ranges from 20-40%. Development of ACR is associated with increased risk of graft…
  • 2019 American Transplant Congress

    CD4 T Cell is Essential in an Innate-Immune Driven Ischemia-Reperfusion Injury in Mouse and Human

    S. Kageyama1, K. Kadono1, H. Hirao1, K. Nakamura1, T. Ito2, K. J. Dery1, D. Oncel1, R. A. Sosa3, E. F. Reed3, F. M. Kaldas2, R. W. Busuttil2, J. W. Kupiec-Weglinski1, Y. Zhai1

    1Surgery, Dumont-UCLA Transplant Center, Los Angeles, CA, 2Surgery, Ronald Reagan UCLA Medical Center, Los Angeles, CA, 3Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA

    *Purpose: Although CD4 T cells are critical in the mechanism of allograft rejection, little is known about their role in the innate immune-driven ischemia-reperfusion injury…
  • 2019 American Transplant Congress

    Prolonged Cold Ischemic Storage Induces Allograft Necro-Inflammation That Increases Graft Susceptibility to T Cell Mediated Rejection

    N. Chun1, R. Ang1, J. Horwitz1, R. Fairchild2, W. Baldwin III2, A. Ting1, P. S. Heeger1

    1Icahn School of Medicine at Mount Sinai, New York, NY, 2Cleveland Clinic, Cleveland, OH

    *Purpose: Prolonged cold ischemic storage (CIS) of murine cardiac allografts causes complement dependent, CTLA4Ig-resistant rejection that is associated with 48h post-transplant elevations in serum levels…
  • 2019 American Transplant Congress

    Variations in Recipient and Donor Clinical Characteristics between Kidney Transplant Centers

    W. T. McKinney1, M. Bruin2, S. Chu2, D. Schladt3, J. Snyder3, A. Matas4, B. Kasiske5, A. K. Israni3

    1Nephrology, Hennepin Healthcare Research Institute, Minneapolis, MN, 2College of Design, University of Minnesota, St. Paul, MN, 3Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN, 4Department of Surgery, University of Minnesota, Minneapolis, MN, 5Department of Medicine, Hennepin Healthcare, Minneapolis, MN

    *Purpose: When a patient can choose at which kidney transplant program to establish care, prior knowledge of program acceptance practices (of candidates and donors) can…
  • 2019 American Transplant Congress

    How Much Does Graft Function Cost Us? A Financial Analysis of Delayed Graft Function in Kidney Transplant Recipients

    A. Yaldo, I. Bajjoka, C. Crombez, M. Abouljoud

    Henry Ford Transplant Institute, Detroit, MI

    *Purpose: Kidney transplant recipients (KTR) who receive dialysis post-transplant experience worse outcomes during the first year post-transplant. Whether KTR discharged with elevated levels of serum…
  • 2019 American Transplant Congress

    Clinical Utility of a Pharmacogenomic Testing Tool among Kidney Transplant Recipients

    S. LeCorchick, L. Lindberg, W. Stapley, S. Anand, D. Morris, T. Srinivas

    Kidney/Pancreas Transplant Program, Intermountain Medical Center, Murray, UT

    *Purpose: Therapeutic drug monitoring (TDM) for tacrolimus (Tac) is the cornerstone of clinical workflow in the transplant clinic. We report on the clinical implementation of,…
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