ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Scaffold-Free 3D-Bioprinting of Human Extrahepatic Bile Duct

    K. Saglam1, W. Zhang1, L. J. Smith2, A. Isidan1, A. M. Chen1, R. A. Naqvi1, E. Gramelspacher1, P. Li1, B. Ekser1

    1Transplant Division, Department of Surgery, Indiana University, Indianapolis, IN, 23D-Bioprinting Core, Indiana University School of Medicine, Indianapolis, IN

    *Purpose: Biliary complications are common especially in living and also in deceased donor liver transplantation (LT). Presence of multiple orifices in biliary anastomosis and ischemia,…
  • 2019 American Transplant Congress

    Identification of Relevant Renal Transplant Patient Reported Symptoms That Could Be Used for New Patient Reported Outcome Development

    I. Purnajo1, J. Beaumont1, M. Polinsky2, E. Alemao2, M. J. Everly1

    1Terasaki Research Institute, Los Angeles, CA, 2Bristol Myers Squibb, Princeton, NJ

    *Purpose: We analyzed post-transplant health-related quality of life (HRQoL) and symptom experience captured longitudinally in the belatacept vs. cyclosporine (BENEFIT and BENEFIT-EXT) trial cohorts to…
  • 2019 American Transplant Congress

    Identification of Rare Genetic Disorders in Kidney Transplantation Recipients with Un-Diagnosed Nephropathy through NGS Approach

    G. Castellano, M. Giliberti, P. Pontrelli, M. Gigante, S. Diella, M. Accetturo, E. Stea, A. Mitrotti, L. Gesualdo

    Emergency and Organ Transplantation, University of Bari, Bari, Italy

    *Purpose: About 10% of end stage renal disease (ESRD) patients have no diagnosis of the primary kidney disease. Patients with unknown renal pathology can access…
  • 2019 American Transplant Congress

    Arteriovenous Fistula Ligation In Stable Renal Transplant Patients Does Not Adversely Influence Graft Function

    A. Han, S. Ahn, S. Min, S. Min, S. Kim, J. Ha

    Department of Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of

    *Purpose: Whether or not to ligate functioning arteriovenous fistula (AVF) after renal transplantation remains controversial. Recently, there have been several reports showing that the presence…
  • 2019 American Transplant Congress

    Outcomes of Phenotypes in Early Subclinical Inflammation (SCI) Determined by Presence of Interstitial Inflammation with or without Concomitant Tubulitis

    R. Mehta, S. Tandukar, D. Jorgensen, I. Owoyemi, P. Sood, A. Tevar, S. Hariharan

    University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: Low levels of renal allograft inflammation in the early post transplant period appear to have an impact on renal architecture and function. However, the…
  • 2019 American Transplant Congress

    Use of GLP-1 Receptor Agonists in Kidney Transplant Recipients with Type 2 Diabetes

    A. Kukla, J. Hill, M. Merzkani, A. Bentall, E. Lorenz, W. Park, P. Shah, N. Issa, M. Stegall

    Mayo Clinic, Rochester, MN

    *Purpose: GLP-1 receptor agonists have been shown to improve glucose control and diabetes-related comorbidities, including obesity, cardiovascular disease and chronic kidney disease, in non-transplant patients.…
  • 2019 American Transplant Congress

    Tacrolimus Activated BMP Signaling Acts in Synergy with Stress-Activated FOXO1 to Induce Loss of Beta-Cell Function and Identity

    J. Trinañes1, P. ten Dijke2, T. J. Rabelink3, E. J. de Koning4, F. Carlotti1, A. P. de Vries1

    1Transplant Center, Leiden University Medical Center, Leiden, Netherlands, 2Molecular Cell Biology, Leiden University Medical Center, Leiden, Netherlands, 3of Nephrology, Leiden University Medical Center, Leiden, Netherlands, 4Nephrology, Leiden University Medical Center, Leiden, Netherlands

    *Purpose: Tacrolimus, the most widely used immunosuppressive drug, is known to be highly diabetogenic. It is thought to trigger β-cell death through inhibition of the…
  • 2019 American Transplant Congress

    Intracerebral Hemorrhage in Renal Transplant Recipients with Autosomal Dominant Polycystic Kidney Disease: A Nationwide Analysis

    W. Cheungpasitporn1, C. Thongprayoon2, P. Ungprasert3, K. Wijarnpreecha4, F. T. Chebib2, P. T. Kroner4

    1Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, 2Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, 3Clinical Epidemiology Unit, Department of Research and Development, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand, 4Department of Medicine, Mayo Clinic, Jacksonville, FL

    *Purpose: This study aimed to evaluate the hospitalization rate for intracerebral hemorrhage (ICH) among renal transplant patients with adult polycystic kidney disease (ADPKD) and its…
  • 2019 American Transplant Congress

    HLA-DR Upregulation in Pediatric Kidney Transplant Biopsies

    O. Moussa, S. Self, E. Bruner, K. Twombley

    Medical University of South Carolina, Charleston, SC

    *Purpose: Renal tubular epithelial cells do not typically express human leukocyte antigen DR (HLA-DR). It’s expression has been associated with different types of tubular injury…
  • 2019 American Transplant Congress

    Differences in Graft Survival for Pediatric and Adult Kidney Recipients Followed and Lost to Follow-Up

    A. M. Robinson1, E. K. Hsu2, S. M. Bartosh3, D. E. Stewart1, G. V. Mazariegos4

    1United Network for Organ Sharing, Richmond, VA, 2Seattle Children's Hospital, Seattle, WA, 3University of Wisconsin Hospital and Clinics, Madison, WI, 4Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA

    *Purpose: While the majority of kidney transplant recipients are followed by their program, many end up reported to the OPTN as lost to follow-up (LTFU).…
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