2019 American Transplant Congress
Urinary Injury Biomarkers in Deceased Donors and Acute Rejection Post Kidney Transplant
*Purpose: Acute kidney injury (AKI) is common among deceased kidney donors. We hypothesized that inflammation from kidney injury could lead to enhanced expression of HLA…2019 American Transplant Congress
Earlier Transplant Education as CKD Progresses? CKD 3-5 Patients and Providers Weigh In
*Purpose: To increase preemptive and early transplant rates, transplant education must be delivered along the entire chronic kidney disease (CKD) spectrum. To understand patients’ education…2019 American Transplant Congress
Evolution of HHV6- and CMV-Specific T Cell Functional Responses and Immune Cell Populations after Kidney Transplant
*Purpose: Human herpesvirus (HHV)-6 reactivation after solid organ or hematopoietic stem cell transplant has been associated with complications such as graft rejection and all-cause mortality.…2019 American Transplant Congress
The Increasing Financial Challenge of Liver Transplantation
*Purpose: Despite innovations in clinical care, liver transplant (LT) remains highly resource intensive due to medical complexity and organ quality. National allocation systems prioritize access…2019 American Transplant Congress
p40 Homodimer Indirectly Induce Proliferation of Endogenous Donor-Reactive Memory CD8 T Cells within High-Risk Allografts via IL-15 Signaling
Inflammation and Immunity, Cleveland Clinic, Cleveland, OH
*Purpose: Increasing the duration of cold ischemic storage (CIS) from 0.5 to 8 hrs prior to transplant induces the increased proliferation of endogenous donor-reactive CD4…2019 American Transplant Congress
The End of Non-Directed Living Kidney Donation: The National Kidney Registry’s Family Voucher Program
*Purpose: The continued growth of the National Kidney Registry’s (NKR) Voucher program has extended Kidney Paired Donation (KPD) to include chronological incompatibility which is facilitating…2019 American Transplant Congress
Improving Medication Adherence and Outcomes in Adult Kidney Transplant Patients Using SystemCHANGETM: Results of the Medication Adherence Given Individual Change (MAGIC) Randomized Clinical Trial
*Purpose: Medication non-adherence is an obdurate problem associated with poor outcomes and staggering costs. Even with multi-faceted interventions, effect sizes reported in meta-analyses of medication…2019 American Transplant Congress
The Benefit of Kidney Transplantation over the Waitlist Depends on the Patient’s Comorbidities
*Purpose: This study aimed to determine the impact of different comorbidities to the survival benefit of Kidney Transplantation (KTx) compared to waitlisted (WL) patients in…2019 American Transplant Congress
Donation after Cardiac Simultaneous Liver-Kidney: An Updated Perspective
*Purpose: Historically, the outcomes from donation after cardiac death (DCD) donors have been shown to be inferior as compared to those of donation after brain…2019 American Transplant Congress
Selective CD28 Blockade-Mediated Inhibition of T Follicular Helper Cell and DSA Responses is CTLA-4 Dependent
Emory Transplant Center, Atlanta, GA
*Purpose: Clinical costimulation blockade of the CD28 pathway in the form of CTLA-4Ig has shown the ability to attenuate T cell dependent DSA responses. However,…
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