ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Pneumocystis Prophylaxis in Solid Organ Transplant Recipients at Two Large Transplant Centers from 2015-2016: Why Not Trimethoprim-Sulfamethoxazole?

    J. M. Lum1, V. Athans2, I. Echenique3, C. E. Koval1

    1Infectious Diseases, Cleveland Clinic Floundation, Cleveland, OH, 2Infectious Diseases, University of Pennsylvania, Philadelphia, PA, 3Infectious Diseases, Cleveland Clinic Florida, Weston, FL

    *Purpose: Trimethoprim-sulfamethoxazole (T/S) is the drug of choice for Pneumocystis jirovecii pneumonia (PJP) prophylaxis (ppx) after solid organ transplant (SOT). Perceived side effects may lead…
  • 2019 American Transplant Congress

    Infectious Complications in 71 Heart Transplant Recipients at King Chulalongkorn Memorial Hospital, Thailand

    N. Sangpornsuk1, J. Wanichwatphibun2, A. Ariyachaipanich3, P. Ongcharit4, K. Jutivorakool5, J. Vanichanan5

    1Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, 2Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, 3Excellent Center for Organ Transplantation, King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 4Cardiothoracic Surgery Unit, Department of Surgery, King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 5Division of Infectious Diseases, Department of Medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand

    *Purpose: Infections have been known as one of the major complication associated with morbidity and mortality especially in the first year following orthotropic heart transplantation…
  • 2019 American Transplant Congress

    Fractalkine is Crucial in Ischemia Reperfusion Injury Related to Acute Rejection in an Allogeneic Heart Transplantation Model

    T. Kanzawa1, D. Tokita1, T. Yamakawa1, H. Ishigooka1, H. Fukuda1, H. Katsumata1, S. Miyairi1, R. Ishii1, T. Hirai1, K. Saiga1, M. Okumi1, T. Imai2, K. Tanabe1

    1Urology, Tokyo Women's Medical University, Tokyo, Japan, 2KAN Research Institute, Kobe, Japan

    *Purpose: Ischemia reperfusion injury (IRI) facilitates allograft rejection in renal transplantation recipients (IRI-related rejection). Controlling IRI improves graft survival. Fractalkine (FKN) is an inflammatory chemokine.…
  • 2019 American Transplant Congress

    Ceria-Zirconia Nanoparticles as an Enhanced Antioxidant Attenuates Apoptosis of Human Kidney Proximal Tubular Epithelial Cells in Hypoxia

    S. Yoon1, K. Yoon2, S. Hong3, S. Yun1, W. Hwang1, J. Moon4, J. Lee1, H. Jeon1

    1Nephrology, Konyang University Hospital, Daejeon, Korea, Republic of, 2Hannam University, Daejeon, Korea, Republic of, 3Chemistry, Hannam University, Daejeon, Korea, Republic of, 4General Surgery, Konyang University Hospital, Daejeon, Korea, Republic of

    *Purpose: Ischemia/reperfusion injury, resulting from hypoxic damage within a graft, is the leading cause of delayed graft function and graft rejection. Various mechanisms have been…
  • 2019 American Transplant Congress

    CMV-Specific Cell-Mediated Immunity Early after Transplantation Discriminates R+ Transplant Patients at Risk of CMV Infection among Different Solid Organ Transplants

    M. Jarque1, A. Cachero2, E. Garcia-Romero3, L. Lladó2, C. Baliellas2, C. Diez3, E. Melilli4, J. Fabregat2, J. Gonzalez-Costello3, O. Bestard4

    1Experimentall Nephrology laboratory, IDIBELL, L'Hospitalet de Llobregat. Barcelona, Spain, 2Liver Transplant Department, Bellvitge University Hospital, L'Hospitalet de Llobregat. Barcelona, Spain, 3Heart Transplant Unit, Cardiology Department, Bellvitge University Hospital, L'Hospitalet de Llobregat. Barcelona, Spain, 4Kidney Transplantation Unit, Bellvitge University Hospital- IDIBELL, L'Hospitalet de Llobregat. Barcelona, Spain

    *Purpose: While monitoring CMV-specific cell-mediated immunity(CMI) has shown to be effective in predicting the risk of CMV infection, comparisons across different solid organ transplants(SOT) and…
  • 2019 American Transplant Congress

    CNV Screening For End-stage Renal Disease

    C. E. Fishman, B. Chang, A. Shaked, B. J. Keating

    Surgery, University of Pennsylvania, Philadelphia, PA

    *Purpose: The prevalence of ESRD in the United States was 2,160.7 cases per one million individuals in 2016, and a primary cause of ESRD was…
  • 2019 American Transplant Congress

    Paradoxical Differential Post-transplant Rates Of Change Of Serum Proteins In Pediatric Liver Patients With Evidence For A Novel Sarcopenic-dependent Serum Protein Stimulating Factor

    C. M. Schmidt1, J. Molleston2, G. S. Rao2, C. A. Kubal1, S. Atoa1, R. S. Mangus1

    1Surgery, Transplant Division, Indiana University, Indianapolis, IN, 2Pediatrics, Division of GI and Hepatology, Indiana University, Indianapolis, IN

    *Purpose: Pediatric patients with liver disease suffer from hypoalbuminemia, sarcopenia, and malnutrition. This study aims to quantify differential rates of change (ROC) and post-TX normalization…
  • 2019 American Transplant Congress

    Prognostic Value Of Dobutamine Stress Echocardiography In Heart Transplantation Recipients

    A. Singhvi, R. Araujo-Gutierrez, M. H. Park, A. Bhimaraj, B. H. Trachtenberg, I. Hussain, A. Guha

    Division of Cardiology/ JC Walter Jr. Transplant Center, Houston Methodist Hospital, Houston, TX

    *Purpose: Dobutamine stress echocardiography (DSE) carries a class IIa recommendation in the ISHLT guidelines for screening of cardiac allograft vasculopathy (CAV). Positive DSEs have a…
  • 2019 American Transplant Congress

    Idarucizumab For The Reversal Of Dabigatran In Patients Undergoing Heart Transplantation

    J. Van Keer1, T. Vanassche1, W. Droogne1, S. Rex2, F. Rega3, J. Van Cleemput1, P. Verhamme1, M. Naesens4

    1Cardiology, University Hospitals Leuven, Leuven, Belgium, 2Anesthesiology, University Hospitals Leuven, Leuven, Belgium, 3Cardiovascular Surgery, University Hospitals Leuven, Leuven, Belgium, 4Nephrology, University Hospitals Leuven, Leuven, Belgium

    *Purpose: Atrial fibrillation is common among patients with advanced heart failure who are listed for transplantation. Idarucizumab is a monoclonal antibody fragment that was developed…
  • 2019 American Transplant Congress

    Extracorporeal Photopheresis for Specific Immune Tolerance Responses in Heart Transplant Recipients

    M. J. Barten1, K. Klaeske2, J. Wittke2, M. Borger2, J. Garbade2, S. Lehmann3, H. Reichenspurner1, M. Dieterlen2

    1Cardiovascular Surgery, University Heart Center, Hamburg, Germany, 2Cardiac Surgery, University Heart Center Leipzig, Leipzig, Germany, 3Cardiacr Surgery, University Heart Center Leipzig, Leipzig, Germany

    *Purpose: Extracorporeal photopheresis (ECP) treatment following heart transplantation (HTx) may induce transplant tolerance. A monitoring tool for successful ECP treatment would allow determination of patient-specific…
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