Am J Transplant, Volume 19, Suppl 3 Archives - Page 28 of 214 - ATC Abstracts

2019 American Transplant Congress
Wide Geographic Variability in the Proportion of Donors with Cardiac Death – Lost Opportunities for Organ Donation?
E. M. Sonnenberg¹, D. S. Goldberg², J. Y. Hsu³, P. P. Reese², P. L. Abt¹
¹Department of Surgery, University of Pennsylvania, Philadelphia, PA, ²Department of Medicine, University of Pennsylvania, Philadelphia, PA, ³Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA
*Purpose: Donation after cardiac death (DCD) donors are largely not considered by organ procurement organization (OPO) metrics, as DCD donors are only counted in donor…
2019 American Transplant Congress
Role of NF-kB in Release of Isletokines via Exosomes in Response to Islet Stress
P. Saravanan¹, M. Kanak¹, J. Kalivarathan¹, M. Lawrence², M. Levy¹, B. Naziruddin³
¹Department of Surgery, Virginia Commonwealth University, VCU Health, Richmond, VA, ²Islet Cell Lab, Baylor Scott and White Research Institute, Dallas, TX, ³Simmons Transplant Institute, Baylor Scott and White Medical Center, Dallas, TX
*Purpose: Human islets are exposed to a range of inflammatory stimuli upon transplantation that leads to poor graft survival. Identifying the various signaling events may…
2019 American Transplant Congress
Success in Lung Transplantation Outcomes after Receiving a Standardized Desensitization Therapy
S. Ganesh¹, C. L. Prohaska², C. Mares², M. J. Everly³
¹Medicine, Keck Medical Center at the University of Southern California, Los Angeles, CA, ²BioMatrix, Weston, FL, ³Terasaki Research Institute, Los Angeles, CA
*Purpose: With a goal to develop a safe, effective, and consistent approach to desensitization therapy using IVIg in lung transplant (LuT), we instituted a standard…
2019 American Transplant Congress
Pancreata From Donors With Renal Insufficiency: Viable For Transplant?
X. Luo¹, J. Garonzik Wang², M. B. Doyle¹, A. Khan¹, T. Alhamad³, W. C. Chapman¹, A. Massie², D. Segev², J. R. Wellen¹
¹Section of Abdominal Transplant Surgery, Washington University School of Medicine, St. Louis, MO, ²Department of Surgery, Johns Hopkins University, Baltimore, MD, ³Division of Nephrology, Washington University School of Medicine, St. Louis, MO
*Purpose: Pancreata are declined for transplantation for a multitude of reasons. Some of those reasons are organ edema as well as the potential for ischemic…
2019 American Transplant Congress
The Effect Of Exclusive Virtual Crossmatch To Allocate Deceased Donor Kidney Transplant On Cold Ischemia Time And Acute Rejection
E. Abuhelaiqa¹, M. Alkadi¹, S. Thappy¹, S. Saleh², J. Mahmoud³, M. Jarman³, O. Fituri¹, M. Elkhalifa⁴, J. Wadström³, H. Al-Malki¹
¹Medicine-Nephrology, Hamad Medical Corporation, Doha, Qatar, ²Histocompatibility & Immunogenetics Laboratory,, Hamad Medical Corporation, Doha, Qatar, ³Surgery-Transplant, Hamad Medical Corporation, Doha, Qatar, ⁴Histocompatibility & Immunogenetics Laboratory, Hamad Medical Corporation, Doha, Qatar
*Purpose: Virtual crossmatch (VXM) using Luminex single antigen bead has significantly improved prediction of an actual negative crossmatch. A negative crossmatch is typically required for…
2019 American Transplant Congress
Presence of DSA Class 2 is Associated with Fibrosis Progression after OLT
M. Sterneck¹, B. Sultani², M. Rodriguez Lago³, E. Grabhorn⁴, A. Briem-Richter⁴, U. Herden⁵, L. Fischer⁵
¹University Medical Center Hamburg Eppendorf, Hamburg, Germany, ²University Transplant Center, University Medical Center Hamburg Eppendorf, Hamburg, Germany, ³Depatment of Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany, ⁴Department of Paediatric Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany, ⁵Department of Visceral Transplantation, University Medical Center Hamburg Eppendorf, Hamburg, Germany
*Purpose: For decades, donor-specific antibodies (DSA) have been thought not to be clinically relevant in orthotopic liver transplantation (OLT). However, recent studies have shown a…
2019 American Transplant Congress
Chronic Changes on Time Zero Living Donor Allograft Biopsy Do Not Portend Future Kidney Function
A. Agarwal¹, A. Sites², K. L. Brayman¹, A. Doyle³, J. Oberholzer¹, A. Nishio-Lucar³
¹Surgery, University of Virginia, Charlottesville, VA, ²Transplant, University of Virginia, Charlottesville, VA, ³Medicine, University of Virginia, Charlottesville, VA
*Purpose: The predictive ability of implantation biopsies of kidney allografts on either future recipient or living donor kidney function has not been fully elucidated. Herein,…
2019 American Transplant Congress
A Novel Genomic Approach for Acute Rejection across All Age Groups in Kidney Transplantation
B. I. Shaw, D. K. Cheng, Q. Cheng, C. R. Acharya, A. D. Kirk, E. T. Chambers
Pediatrics/Surgery, Duke University, Durham, NC
*Purpose: Acute Rejection remains a significant complication in kidney transplantation that affects long-term outcomes. Using a large collection of gene expression data obtained from multiple…
2019 American Transplant Congress
Local IL-33 Regulates Heart Transplant Infiltrating Myeloid Cells Metabolism and Differentiation to Protect against Chronic Rejection
Z. Zhang¹, Q. Liu¹, T. Li¹, G. S. Hussey², M. Velayutham¹, J. L. Dziki², L. R. Mathews¹, Y. C. Lee², G. K. Dwyer¹, H. Dai¹, A. S. Roessing¹, S. Shiva³, M. H. Oberbarnscheidt¹, S. F. Badylak², H. R. Turnquist¹
¹Department of Surgery, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, ²Department of Bioengineering, McGowan Institute for Regenerative Medicine, Pittsburgh, PA, ³Department of Pharmacology and Chemical Biology, Vascular Medicine Institute, Pittsburgh, PA
*Purpose: Self-molecules containing damage-associated molecular patterns stimulate the pro-inflammatory response of infiltrating innate immune cells after their release during tissue injury. Yet, if local endogenous…
2019 American Transplant Congress
Renal Recovery and Prognostic Factors in Children Following Liver Transplantation
R. Büscher, N. Gantenberg, A. Büscher, E. Lainka, P. Hoyer
Department of Pediatrics II, University Hospital Essen, Essen, Germany
*Purpose: Progression to chronic renal disease (CKD) is highly prevalent in adults following liver transplantation (LT) with a profound impact on patient survival, assuming that…