Am J Transplant, Volume 19, Suppl 3 Archives - Page 27 of 214 - ATC Abstracts

2019 American Transplant Congress
The Effect of Intravenous Immunoglobulin on Human Complement-Dependent Cytotoxicity of Pig Cells: Benefit? Or Harm?
T. Yamamoto¹, Q. Li¹, A. Banks¹, H. Iwase¹, D. Ayares², D. K. Cooper¹, H. Hara¹
¹Xenotransplantation Program, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, ²Revivicor, Blacksburg, VA
*Purpose: Xenoreactive antibodies and complement play an important role in pig xenograft rejection. Intravenous immunoglobulin (IVIG) is widely used in desensitization protocols and for the…
2019 American Transplant Congress
Incidence of De Novo Donor Specific Antibodies and Treatment Response for AMR in Pediatric Kidney Transplant Recipients
S. Gattis¹, R. Liverman¹, A. Serluco¹, J. Yin¹, H. C. Sullivan², R. A. Bray³, H. M. Gebel³, S. Jernigan⁴, R. George⁴, P. D. Winterberg⁴, R. Garro⁴
¹Children's Healthcare of Atlanta, Atlanta, GA, ²Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, ³Emory University Hospital, Atlanta, GA, ⁴Department of Pediatrics, Emory University School of Medicine, Atlanta, GA
*Purpose: Antibody-mediated rejection (AMR) is a significant complication in renal transplant patients. The aim of this study was to evaluate the incidence of de novo…
2019 American Transplant Congress
Long Term Impact of Intraoperative Autologous Blood Transfusion on HCC Recurrence in Liver Transplantation
G. Kelly¹, J. L. Pasko¹, E. Dewey², E. Maynard¹, S. L. Orloff¹, C. Enestvedt¹
¹Division of Abdominal Transplant, OHSU, Portland, OR, ²Department of General Surgery, OHSU, Portland, OR
*Purpose: The aim of this study was to determine whether intraoperative autologous transfusion in liver transplant patients with HCC affects the rate of recurrence.*Methods: We…
2019 American Transplant Congress
Discovery and Validation of Blood Genomic Signatures of Acute Rejection in Liver Transplant Recipients
J. Levitsky¹, N. Bridges², J. Odim², M. Brown², D. Ikle³, B. Armstrong³, A. Demetris⁴, S. Asrani⁵, G. Klintmalm⁵, T. Schiano⁶, A. Moss⁷, K. Chavin⁸, C. Miller⁹, M. Kandpal¹⁰, L. Zhao¹⁰, S. Kurian¹¹, M. Abecassis¹⁰
¹Div of Gastroenterology & Comprehensive Tx Cnt, Chicago, IL, ²NIAID, Bethesda, MD, ³Rho, Chapel Hill, NC, ⁴UPMC, Pittsburgh, PA, ⁵Baylor, Dallas, TX, ⁶Mount Sinai, New York, NY, ⁷Mayo Arizona, Phoenix, AZ, ⁸Case Western, Cleveland, OH, ⁹Cleveland Clinic, Cleveland, OH, ¹⁰Comprehensive Transplant Center, Chicago, IL, ¹¹Scripps, San Diego, CA
*Purpose: Biomarker profiles diagnostic of acute rejection (AR) could enhance the management of liver transplant (LT) recipients. Our aim was to discover and validate blood…
2019 American Transplant Congress
A Regulatory T Cell-Intrinsic Role for Ikaros in Acquired Transplant Tolerance
R. M. Thomas, L. Wang, W. W. Hancock, A. D. Wells
The Children's Hospital of Philadelphia, Philadelphia, PA
*Purpose: Ikaros is a transcriptional repressor encoded by the Ikzf1 gene that was recently identified as the pharmacologic target of thalidomide analogs in successful therapy…
2019 American Transplant Congress
Early T Cell Infiltration is Modulated by PD-1/PD-L1 Interactions in Kidney Graft
Y. Shim, R. Fan, N. Dvorina, W. Baldwin
Inflammation and Immunity, Lerner Research Institute, Cleveland, OH
*Purpose: Allogeneic transplants elicit dynamic T cell responses that are modulated by positive and negative co-stimulatory receptors. We have investigated the impact of PD-1, a…
2019 American Transplant Congress
The Impact of Race on Metabolic, Graft and Patient Outcomes after Pancreatic Transplantation
V. S. Rohan, S. N. Nadig, J. Mcgillicuddy, V. Rao, D. Dubay, K. Soliman, P. Baliga, D. Taber
Transplant Surgery, Medical University of South Carolina, Charleston, SC
*Purpose: Health disparities in African-Americans (AAs) are well-documented in kidney transplantation. There is a paucity of data regarding effect race in pancreas transplant (PTX) outcomes.*Methods:…
2019 American Transplant Congress
Cost-Effectiveness Analysis of Renal Replacement Therapy Strategies in Haiti
J. S. Pyda¹, L. James², J. J. Kim², K. Khwaja¹, M. Shrime³
¹Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, ²Center for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, MA, ³Program in Global Surgery and Social Change, Harvard Medical School, Boston, MA
*Purpose: Kidney transplantation (KT) is the optimal renal replacement therapy (RRT) for patients with end-stage renal disease (ESRD) in high-income countries (HICs) conferring the highest…
2019 American Transplant Congress
Anti-Xa Level Monitoring for Treatment Dose Enoxaparin in Liver/Intestine Transplant Recipients
J. Sullivan, J. Jebrock, J. Revollo, M. Perez, J. Garcia, T. Beduschi
Jackson Memorial Hospital, Miami, FL
*Purpose: Evaluate the use of anti-Xa levels in therapeutic enoxaparin dosing in liver/intestine transplant recipients.*Methods: A single-center retrospective chart review was conducted on liver/intestine transplant…
2019 American Transplant Congress
A Multi National Study Ofkidney Transplantation In Inmates
Y. Qazi, A. Mahajan, D. Bahl, F. Jan
Keck Medical Center at USC, Los Angeles, CA
*Purpose: Over 10 million inmates exist in prison worldwide, with United States accounting for over fifth of this population. The number of inmates with ESRD…