Am J Transplant, Volume 19, Suppl 3 Archives - Page 182 of 214 - ATC Abstracts

2019 American Transplant Congress
“What I Wish I Would Have Known….” Patient Impressions of Transplant Education
K. Collins¹, A. Yaldo¹, E. Rubinstein¹, K. Kippen², H. Olden², S. Nagai¹, M. Abouljoud¹
¹Henry Ford Transplant Institute, Detroit, MI, ²Henry Ford, Detroit, MI
*Purpose: Personal health management remains a key component to adherence after transplantation. The purpose of this study was to identify potential gaps in transplant education.…
2019 American Transplant Congress
Stakeholder Perspectives in Peer Mentoring Program for Pediatric Solid Organ Transplant Recipients
C. Strachan, M. Paton, J. Reason, S. Amaral
Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA
*Purpose: This study analyzed feedback surveys from Peers4PATH, a peer mentoring program, aimed to improve medication adherence and health related quality of life (HRQOL) in…
2019 American Transplant Congress
Organ Vigilance in Germany: Malignancy Transmission from Organ Donor to Recipient
K. Moench, A. Rahmel, A. P. Barreiros
German Foundation for Organtransplantation, Frankfurt, Germany
*Purpose: Vigilance monitoring after organ transplantation includes Serious Adverse Events (SAE) and Serious Adverse Reactions (SAR). SAE describe findings in the donor after transplant that…
2019 American Transplant Congress
Mismatched Antibody Epitopes and the Development of HLA-DQ De Novo DSA during Immunosuppression Withdrawal in Liver Transplant Recipients
V. Jucaud¹, A. Shaked², M. DesMarais³, P. Sayre⁴, S. Feng⁴, J. Levitsky⁵, M. Everly¹
¹Terasaki Research Institute, Los Angeles, CA, ²University of Pennsylvania, Philadelphia, PA, ³Immune Tolerance Network, San Francisco, CA, ⁴University of California San Francisco, San Francisco, CA, ⁵Northern Western University, Chicago, IL
*Purpose: We recently described, in liver transplant (LT) recipients from the ITN030ST study, the development of de novo donor-specific HLA antibodies (dnDSA) and their impact…
2019 American Transplant Congress
Supercooling Preservation Prolonged Mouse Cardiac Graft Cold Ischemia Time
W. Que¹, X. Hu¹, M. Fujino¹, Y. Yamada², L. Zhong³, X. Li¹
¹Division of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan, ²Technican Co., Ltd., Kanagawa, Japan, ³Department of Surgery, Shanghai General Hospital, shanghai Jiao Tong University School of Medicine, Shanghai, China
*Purpose: Supercooling preservation techniques store a donor organ below 0°C without freezing. This has great advantages in inhibiting metabolism and preserving the organ in comparison…
2019 American Transplant Congress
Renal Cell Carcinoma in Dialysis Patients: Criteria for Transplant Wait List Inclusion
D. B. Laskar¹, J. Zeng¹, S. Sharma², M. T. Smith Jr³, A. D. Nicastri¹, D. Levitan⁴, R. Maglantay¹, D. John³, S. R. Gottesman¹
¹Pathology, SUNY Downstate Medical Center, Brooklyn, NY, ²Transplant Surgery, NYP/Columbia University Medical Center, New York, NY, ³Surgery, SUNY Downstate Medical Center, Brooklyn, NY, ⁴Pathology & Laboratory Medicine, NYP/Weill Cornell Medical Center, New York, NY
*Purpose: End-stage renal disease (ESRD) patients on long-term hemodialysis have a higher incidence of renal cell carcinoma (RCC) in their native kidneys than the general…
2019 American Transplant Congress
Associations between State-Level Donor Designation Rate and Organ Procurement Organization Characteristics and Outcomes
J. Bragg-Gresham¹, P. Held², J. P. Roberts³
¹Kidney Epidemiology and Cost Center, Univ of Michigan, Ann Arbor, MI, ²Stanford University, Stanford, CA, ³University of California San Francisco, San Francisco, CA
*Purpose: The impact of “Donor Designation (DDSR)”, a pledge to donate with state drivers licensing authority, has not been explored. This work focusses on estimating…
2019 American Transplant Congress
In Vivo/In Situ Behaviour of Allogeneic Spleen versus Bone Marrow Cells in Wild-Type Neonatal Mice: Insights into Robust Transplant Tolerance Induction
R. A. Bascom, K. Tao, L. J. West
Pediatrics, University of Alberta, Edmonton, AB, Canada
*Purpose: Comparing the behaviour of fully allogeneic spleen (SC) vs bone marrow cells (BMC) in non-conditioned neonatal mice is important for maximizing synergistic interactions between…
2019 American Transplant Congress
ECDI-Treated Donor Leukocytes in Primate Cardiac Allograft Recipients
Z. Alikhassy Habibabady¹, T. Zhang², W. Sun², X. Cheng², L. Burdorf¹, I. Tatarov², S. Sendil², I. Behroozfard², B. Cerel¹, D. Parsell², R. N. Pierson III¹, X. Luo³, A. M. Azimzadeh¹
¹Surgery, Massachusetts General Hospital and Harvard School of Medicine, Boston, MA, ²Surgery, University of Maryland School of Medicine, Baltimore, MD, ³Duke Transplant Center, Duke University, Durham, NC
*Purpose: Ethyl carbodiimide (ECDI)-fixed donor leukocytes exhibit tolerogenic immunomodulation in murine models of autoimmunity and transplantation, and nonhuman primate islet transplantation. Here in pilot studies…
2019 American Transplant Congress
TMA Development in Kidney and Heart Xenografts Treated with Anti-CD40 or Anti-CD154 Antibodies
D. H. Ma¹, H. Sasaki¹, J. M. O¹, K. Ahrens¹, D. Becerra¹, C. G. Rickert¹, D. M. Detelich¹, T. Oura¹, W. Somer¹, I. Rosales², R. N. Pierson¹, J. Markmann¹, J. C. Madsen¹, T. Kawai¹
¹Surgery, MGH, Boston, MA, ²Pathology, MGH, Boston, MA
*Purpose: Genetically modified Galactose-α 1,3-galactose knockout transgenic swine expressing human CD55 (GTKO.hCD55) are resistant to hyperacute rejection of xenografts. We compare anti-CD154 and anti-CD40 antibody-based…