ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Proximal Splenic Artery Embolization Is A Safe And Effective Tool To Treat Two Sides Of The Same Coin After Liver Transplant: Persistent High Hepatic Artery Resistive Index And Refractory Ascites And Hydrothorax Due To Portal Hyperperfusion

L. Lomaglio, H. Matsushima, A. Simioni, G. D'Amico, T. Diago Uso, K. Hashimoto, B. Eghtesad, M. Fujiki, F. Aucejo, K. Sasaki, C. Kwon, C. Coppa, M. Bayona Molano, C. Miller, C. Quintini

Cleveland Clinic, Cleveland, OH

Meeting: 2019 American Transplant Congress

Abstract number: B324

Keywords: Hemodynamics, Post-operative complications, Ultrasonography

Session Information

Date: Sunday, June 2, 2019

Session Name: Poster Session B: Liver Retransplantation and Other Complications

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall C & D

Related Abstracts
  • Proximal Splenic Artery Embolization For Refractory Ascites And Hydrothorax After Liver Transplant: A Single Center Analysis Of Factors Associated With Success
  • Splenic Artery Embolization in Liver Transplantation: A Single Center 5 Year Experience

*Purpose: Portal hyperperfusion(PHP) is a polymorphic and dangerous condition in liver transplant(LT) recipients.The aim of the present study was to assess the safety and the efficacy of proximal splenic artery embolization(SAE) as the treatment of choice for high hepatic artery resistive index(HA RI), refractory ascites(RA) and/or refractory hydrothorax(RH), all representing clinical manifestations of PHP.

*Methods: We conducted a retrospective analysis of all patients who underwent SAE for PHP between 2007 and 2017 at our center. Qualitative data were described using number and percent. Quantitative data were described using mean and standard deviation. Continuous variables were compared by unpaired t test and categorical variables were compared by chi square test.

*Results: Ninety-seven patients developed PHP after LT between 2007 and 2017 and underwent SAE. The indication for SAE was elevated HA RI for 63 patients (65%) and RA and/or RH for the remaining 34 patients (35%). No significant differences were observed between the 2 groups in terms of demographic and peri-operative characteristics, with the exception for the presence of ascites in the pre transplant period in 94% of patients who later developed RA/RH against 78% of the high HA RI group (p-value = 0.04). The mean interval of follow-up after SAE was 71 ± 41 months. Normalization of liver vascular ultrasound parameters was achieved in all cases after SAE, with significant decrease of HA RI and PV velocity and concomitant increase of HA peak systolic velocity(PSV) (figure 1). The time interval between LT and SAE was 3(0-12) days in the high HA RI group and 38(7-1675) days in the RA/RH group. The median time between SAE and resolution of clinical manifestation of PHP was 1(0-13) days in the HA RI group and 34(3-762) days in the RA/RH group. Overall, the procedure was very well tolerated, with minimal incidence of post splenectomy syndrome (3 cases, 3%). Partial and subclinical splenic infarcts were incidentally discovered in 24 patients (24.7%). No cases of splenic abscess or systemic sepsis related to possible hyposplenism occurred.

*Conclusions: To our knowledge, this is the largest case series proving the safety and the effectiveness of SAE in reversing PHP and normalizing intrahepatic hemodynamics after LT. However, the clinical impact of this procedure (i.e. reduction of vascular and biliary complications) will need to be further investigated in future studies.

 border=

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Lomaglio L, Matsushima H, Simioni A, D'Amico G, Uso TDiago, Hashimoto K, Eghtesad B, Fujiki M, Aucejo F, Sasaki K, Kwon C, Coppa C, Molano MBayona, Miller C, Quintini C. Proximal Splenic Artery Embolization Is A Safe And Effective Tool To Treat Two Sides Of The Same Coin After Liver Transplant: Persistent High Hepatic Artery Resistive Index And Refractory Ascites And Hydrothorax Due To Portal Hyperperfusion [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/proximal-splenic-artery-embolization-is-a-safe-and-effective-tool-to-treat-two-sides-of-the-same-coin-after-liver-transplant-persistent-high-hepatic-artery-resistive-index-and-refractory-ascites-and/. Accessed March 7, 2021.

« Back to 2019 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Home
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Search
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Home
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Penis Transplantation: First U.S. Experience.
  • A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).
  • Home
  • Search
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.