ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Risk Factors to Define an Extended Criteria Donor Heart Do Not Appear to Have Cumulative Adverse Effects after Heart Transplantation

    M. Olymbios, S. Dimbil, R. J. Levine, F. Esmailian, J. Patel, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: There remains a disparity between the number of patients awaiting heart transplantation (HTx) and the availability of donor hearts. This is exacerbated by relatively…
  • 2019 American Transplant Congress

    Polymorphisms in Mycophenolate Mofetil Glucuronidation Gene Are Associated with Leukopenia and Decreased CLAD-Free Survival

    A. Barnes, D. R. Calabrese, E. Henricksen, R. Florez, K. Dewey, P. Wang, J. Teraoka, K. Lien, S. Hays, J. P. Singer, J. Golden, J. Kukreja, J. R. Greenland

    UCSF Medical Center, San Francisco, CA

    *Purpose: Lung transplant recipients vary in their tolerance of the immunosuppressant mycophenolate mofetil (MMF). Single nucleotide polymorphisms (SNPs) in UDP-glucuronosyltransferase 2B7 (UGT2B7) increase conversion of…
  • 2019 American Transplant Congress

    Association Of Kdpi And Dgf With Dcd Kidney Transplants Outcomes

    M. Sampaio, B. Abdalla, S. Bunnapradist

    David Geffen Sch of Med at UCLA, Los Angeles, CA

    *Purpose: Donors of circulatory death (DCD) have similar outcomes compared to donors of brain death (DBD) in kidney transplants. It is unclear if this is…
  • 2019 American Transplant Congress

    Unique Gene Expression Signatures in Urine Distinguish T Cell Mediated Acute Rejection from BK Virus Nephropathy in Kidney Transplant Patients

    K. S. Keslar1, W. Xu2, A. A. Zmijewska3, K. A. Newell4, J. J. Friedewald5, M. I. Abecassis5, P. S. Heeger6, J. S. Bromberg7, R. B. Mannon3, R. L. Fairchild1

    1Cleveland Clinic, Cleveland, OH, 2Nanostring Technologies, Seattle, WA, 3Univ. Alabama Birmingham, Birmingham, AL, 4Emory Univ., Atlanta, GA, 5Northwestern Univ., Chicago, IL, 6Icahn School of Med., New York, NY, 7Univ. Maryland, Baltimore, MD

    *Purpose: There is a need to develop non-invasive approaches to detect ongoing kidney graft injury and distinguish immune from non-immune inflammation to guide therapy. Ideally…
  • 2019 American Transplant Congress

    Maternal and Pregnancy Outcomes after Living Donor Nephrectomy in a Multistate Cohort

    G. S. Lee1, R. X. Wang2, D. O. Walls3, P. P. Reese4, D. S. Goldberg4, P. L. Abt1

    1Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 2Sidney Kimmel Medical College, Philadelphia, PA, 3Surgery, Rutgers Robert Wood Johnson, New Brunswick, NJ, 4Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA

    *Purpose: Studies have demonstrated increased risk of preeclampsia for pregnancies after kidney donation in homogenous populations or single-center studies. Our study aims to delineate maternal…
  • 2019 American Transplant Congress

    Nationwide Survey of Human T Cell Leukemia Virus Type 1-Infected Kidney Transplant Recipients in Japan

    J. Yamauchi1, Y. Yamano1, M. Matsuoka2, N. Ichimaru3, M. Nishikido4, Y. Shibagaki5, A. Sugitani6, N. Nakamura7, M. Mieno8, K. Yuzawa9

    1Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan, 2Institute for Virus Research, Kyoto University, Kyoto, Japan, 3Advanced Technology for Transplantation, Osaka University, Osaka, Japan, 4Blood Purification Center, Nagasaki University, Nagasaki, Japan, 5Department of Nephrology and Hypertention, St. Marianna University School of Medicine, Kawasaki, Japan, 6NHO Yonago Medical Center, Yonago, Japan, 7Fukuoka University, Fukuoka, Japan, 8Center for Information, Jichi Medical University, Shimotsuke, Japan, 9Department of Transplantation Surgery, National Hospital Organization Mito Medical Center, Ibaraki, Japan

    *Purpose: Human T-cell leukemia virus type 1 (HTLV-1) infects 5 to 10 million people worldwide, and is endemic in Japan, sub-Saharan Africa, South America, and…
  • 2019 American Transplant Congress

    The Clinical & Economic Impact Of Allosensitization In Liver Alone And Simultaneous Liver Kidney Transplantation

    M. Askar1, G. Saracino1, A. Elsabbagh2, J. Fung3, T. Srinivas4, S. Flechner5, J. Trotter1, G. Testa1, B. Kaplan6, G. Klintmalm1, J. Schold5, S. Asrani1

    1Transplant Center, Baylor Scott & White, Dallas, TX, 2St. Vincent Health, Indianapolis, IN, 3University of Chicago Medicine, Chigao, IL, 4Intermountain Healthcare, Salt Lake City, UT, 5Cleveland Clinic, Cleveland, OH, 6Transplant Center, Baylor Scott & White, Temple, TX

    *Purpose: Allosensitization is thought to have marginal impact among patients that undergo liver transplantation (LTA); further among simultaneous liver kidney transplantation (SLKT), livers may protect…
  • 2019 American Transplant Congress

    Rejection Of Optic And Sciatic Transplants

    M. Yonar1, M. Uehara1, V. Kasinath1, F. Bei2, R. Abdi1

    1Renal, Brigham and Women's Hospital, Boston, MA, 2Neurosurgery, Brigham and Women's Hospital, Boston, MA

    *Purpose: Mechanisms of rejection of peripheral nerve and optic nerve remains largely unknown. The inability to prevent rejection of the optic nerve has thwarted the…
  • 2019 American Transplant Congress

    Global Kidney Exchange

    D. N. Bozek1, O. Ekwenna1, S. Paloyo2, T. Dunn3, K. Krawiec4, S. Rees5, A. Roth6, M. Zimmerman7, J. Punch8, R. Forbes9, C. Marsh10, C. Kuhr11, J. Rogers12, M. Tan13, L. Basagoitia14, R. Correa-Rotter15, J. Ortiz1, P. Sindhwani1, M. A. Rees1

    1University of Toledo Medical Center, Toledo, OH, 2University of the Philippines – Philippine General Hospital; St. Luke’s Medical Center, Manila, Philippines, 3University of Minnesota, Minneapolis, MN, 4Duke University, Durham, NC, 5Alliance for Paired Donation, Perrysburg, OH, 6Stanford University, Stanford, CA, 7Froedert Hospital-Medical College of Wisconsin, Milwaukee, WI, 8University of Michigan, Ann Arbor, MI, 9Vanderbilt University Medical Center, Nashville, TN, 10Scripps Green Hospital, San Diego, CA, 11Virginia Mason Medical Center, Seattle, WA, 12Wake Forest Baptist Medical Center, Winston-Salem, NC, 13Piedmont Hospital, Atlanta, GA, 14ProRenal, ., Mexico, 15INNSZ, Mexico City, Mexico

    *Purpose: Poverty prevents more kidney transplants (KTs) worldwide than any other barrier. Global kidney Exchange (GKE) is a mechanism to overcome this barrier.*Methods: In high-income…
  • 2019 American Transplant Congress

    Tacrolimus Concentrations Can Be Reliably Measured in Capillary Microsamples

    M. T. Gustavsen, N. Vethe, M. Lauritsen, A. Andersen, A. Åsberg, S. Bergan, K. Midtvedt

    Oslo University Hospital, Rikshospitalet, Oslo, Norway

    *Purpose: Routine therapeutic drug monitoring (TDM) of tacrolimus (Tac) is currently performed in venous bloods samples drawn at the hospital. The novel volumetric absorptive microsampling…
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