ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Changes in Body Mass Index and Outcomes after Kidney Transplantation: A Single Centre, Retrospective, Observational Study

A. Arshad1, J. Hodson2, K. Khalil1, A. Sharif3

1University of Birmingham, Birmingham, United Kingdom, 2Queen Elizabeth Hospital, Edgbaston, Birmingham, UK, Institute of Translational Medicine, Birmingham, United Kingdom, 3Queen Elizabeth Hospital Birmingham, UK, Department of Nephrology and Transplantation, Birmingham, United Kingdom

Meeting: 2019 American Transplant Congress

Abstract number: C74

Keywords: Kidney transplantation, Weight

Session Information

Date: Monday, June 3, 2019

Session Name: Poster Session C: Kidney Complications: Late Graft Failure

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall C & D

Related Abstracts
  • Early Outcomes of Kidney Transplantation When Comparing Waist-to-Hip Ratio vs. Body Mass Index.
  • Pre-Donation Body Mass Index Associations with Outcomes in Living Kidney Donors: A Single Centre Experience

*Purpose: The aim of this study was to describe the changes in body mass index (BMI) after kidney transplantation and assess how this influences long-term outcomes.

*Methods: Data were collected for all kidney transplant recipients between January 2007 and July 2016. Changes in BMI over the post-transplant period were modelled using a generalised estimating equation. The change in BMI from pre-transplantation to six months was then calculated for each patient. These were categorised into three groups: stable BMI (a change of ±1.5 kg/m2), BMI reduction and BMI increase (changes of >1.5 kg/m2), between which a range of outcomes were compared.

*Results: Data was available for 1,344 patients, who had a geometric mean pre-transplant BMI of 27.3 kg/m2. This declined significantly (P<0.001), to a geometric mean of 25.6 kg/m2 one month after transplantation, before increasing and stabilising to pre-transplant levels by 36 months (geometric mean 27.2 kg/m2, P=0.522) (Figure 1). The n=882 patients with BMI measurements at six months, were divided into groups of reduced (n=303), stable (n=388) and increased (n=131) BMI, relative to pre-transplantation levels. On multivariate analysis, 12-month creatinine levels were significantly higher in the BMI reduction cohort, with adjusted levels of 160.6 μmol/l, compared to 135.0 μmol/l in stable BMI. However, no significant associations were detected between six-month BMI change and patient survival, graft survival, incidence of post-transplant diabetes, cancer, or a range of clinical and histological outcomes (all P>0.05).

*Conclusions: Our data demonstrates that BMI significantly reduces in the first month after kidney transplantation, before increasing to pre-transplant levels at 3-5 years. Furthermore, patients with decreasing BMI at six-months have impaired graft function in the long-term. These observations conflict with the existing literature and warrant further investigation

 border=

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Arshad A, Hodson J, Khalil K, Sharif A. Changes in Body Mass Index and Outcomes after Kidney Transplantation: A Single Centre, Retrospective, Observational Study [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/changes-in-body-mass-index-and-outcomes-after-kidney-transplantation-a-single-centre-retrospective-observational-study/. Accessed March 5, 2021.

« Back to 2019 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Role of Mitochondria, Metabolism and Inflammation: Pathways Influencing Short Term Outcomes Post-Renal Transplantation
    • Factors Influencing Creatinine Rise Following Donor Nephrectomy

    Visit Our Partner Sites

    American Transplant Congress (ATC)

    Visit the official site for the American Transplant Congress »

    American Journal of Transplantation

    The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

    American Society of Transplantation (AST)

    An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

    American Society of Transplant Surgeons (ASTS)

    The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

    Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

    Privacy Policy

    loading Cancel
    Post was not sent - check your email addresses!
    Email check failed, please try again
    Sorry, your blog cannot share posts by email.
    This site uses cookies: Find out more.