Am J Transplant, Volume 19, Suppl 3 Archives - Page 162 of 214 - ATC Abstracts

2019 American Transplant Congress
Patient-Reported Transplant-Related Symptoms in Kidney Transplant Recipients
J. L. Beaumont¹, I. Purnajo¹, M. Polinsky², E. Alemao², M. J. Everly¹
¹Terasaki Research Institute, Los Angeles, CA, ²Bristol Myers Squibb, Princeton, NJ
*Purpose: Kidney transplant (txp) recipients experience many symptoms as a result of their transplant experience, immunosuppressive regimens, and comorbid conditions. The objective of this analysis…
2019 American Transplant Congress
Repeat-Pancreas Transplant after Pancreas Graft Failure in Simultaneous Pancreas and Kidney Transplants is Associated with Better Kidney Graft Survival
S. Parajuli, A. Arunachalam, K. Swanson, F. Aziz, N. Garg, R. Redfield, D. Kaufman, A. Djamali, J. Odorico, D. Mandelbrot
University of Wisconsin, Madison, WI
*Purpose: Simultaneous pancreas and kidney (SPK) transplant is usually the best option for the diabetic ESRD patient. But there is limited information about kidney graft…
2019 American Transplant Congress
Factors Related to International Travel for Transplantation among US-Listed Kidney Transplant Candidates
B. Koons¹, M. L. Henderson², A. G. Thomas³, T. Kear⁴, H. Moriarty⁴
¹School of Nursing, University of Pennsylvania, Philadelphia, PA, ²Department of Surgery in the Division of Transplantation, Johns Hopkins University, Baltimore, MD, ³Department of Epidemiology, University of North Carolina, Chapel Hill, NC, ⁴M. Louise Fitzpatrick College of Nursing, Villanova University, Villanova, PA
*Purpose: The aim of this study was to identify factors associated with international travel for transplantation among US-listed kidney transplant (KT) candidates.*Methods: Using 2010-2016 data…
2019 American Transplant Congress
The Comparative Safety and Efficacy of Direct Acting Oral Anticoagulants Relative to Warfarin Following Liver Transplantation
A. Santeusanio, A. Weinberg, T. Schiano
Mount Sinai Hospital, New York, NY
*Purpose: This study describes the comparative safety and efficacy of direct acting oral anticoagulants (DOACs) relative to warfarin following liver transplantation, at a large academic…
2019 American Transplant Congress
mTORC2 Restricts mTORC1 Metabolic Function in Dendritic Cells to Limit Their Allostimulatory Activity
H. Dai¹, A. Watson¹, A. Menk², D. Stolz³, G. Delgoffe², A. Thomson¹
¹Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, ²Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA, ³Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA
*Purpose: Mechanistic target of rapamycin complex 2 (TORC2) deficiency in conventional dendritic cells (DC) results in their enhanced pro-inflammatory and T cell allostimulatory activity; however,…
2019 American Transplant Congress
Interruption of Notch Signaling via Blockade of Delta-Like Ligands 1 and 4 Prevents Co-Stimulation Blockade Resistant Allograft Rejection
A. Matar, Y. Dong, B. Lovasik, D. Mathews, A. Ghosh, C. Breeden, A. Stephenson, W. Kitchens, A. Adams
Surgery and Transplantation, Emory University, Atlanta, GA
*Purpose: Co-stimulation blockade (CoB) has emerged as a promising immunosuppression strategy with the advent of belatacept, a novel CTLA4-Ig fusion protein that blocks CD28-mediated T…
2019 American Transplant Congress
Apoptosis during Cold Ischemia and Rewarming Involves a Caspase Independent Pathway
S. Jain¹, R. Plenter², T. Nydam², A. Jani¹
¹Renal Division, University of Colorado, Aurora, CO, ²Transplant Microsurgery Program, University of Colorado, Aurora, CO
*Purpose: We have previously shown that hibernating ground squirrels (GS) tolerate core body temperatures of 4°C for several days with a heart rate that is…
2019 American Transplant Congress
A Comprehensive and Updated Analysis of Combined Heart-Kidney Transplants Utilizing the United Network for Organ Sharing Database
V. M. Lim¹, N. Khurmi¹, W. R. Hewitt, Jr.², A. K. Mathur², O. E. Pajaro³, D. E. Jaroszewski³, B. D. Gaitan¹
¹Anesthesiology, Mayo Clinic Arizona, Phoenix, AZ, ²Transplantation Surgery, Mayo Clinic Arizona, Phoenix, AZ, ³Cardiovascular and Thoracic Surgery, Mayo Clinic Arizona, Phoenix, AZ
*Purpose: Analysis of combined heart-kidney transplants (HKTx) reveals equivalent or improved patient survival and reduced allograft rejection rates as compared to single-organ transplants. The rate…
2019 American Transplant Congress
Belatacept Monotherapy in Kidney Transplant Recipients with Failed Allografts Reduces Humoral Sensitization in a Single Center Randomized Controlled Trial
I. R. Badell, R. Elbein, R. A. Bray, H. M. Gebel, A. B. Adams, C. P. Larsen
Emory University School of Medicine, Atlanta, GA
*Purpose: Kidney transplant recipients with failed allografts suffer from high rates of humoral sensitization. Immunosuppression (IS) strategies are highly variable in these patients with many…
2019 American Transplant Congress
AKI and Long-Term Risk for Cardiovascular Events in Patients after Kidney Transplantation
R. Rahamimov¹, M. Molcho², I. Vahav², E. Mor³, T. Y. van Dijk⁴, B. Rozen-Zvi¹
¹Department of Nephrology, Rabin Medical Center, Petach Tikva, Israel, ²Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ³Department of Transplantation, Rabin Medical Center, Petach Tikva, Israel, ⁴Department of Emergency Medicine, Rabin Medical Center, Petach Tikva, Israel
*Purpose: AKI was found to be associated with increased risk of major cardiovascular events (MACE) in the general population. Patients after kidney transplantation are prone…