Am J Transplant, Volume 19, Suppl 3 Archives - Page 127 of 214 - ATC Abstracts

2019 American Transplant Congress
Impact of Multidrug-Resistant Organisms among Donors on Organ Utilization
J. A. Anesi¹, E. Lautenbach¹, J. H. Han¹, D. H. Lee², H. Clauss³, A. Climaco⁴, R. Hasz⁵, E. Molnar³, D. Alimenti¹, S. West⁵, W. B. Bilker¹, P. Tolomeo¹, E. A. Blumberg¹
¹University of Pennsylvania, Philadelphia, PA, ²Drexel University College of Medicine, Philadelphia, PA, ³Temple University, Philadelphia, PA, ⁴Albert Einstein Medical Center, Philadelphia, PA, ⁵Gift of Life Donor Program, Philadelphia, PA
*Purpose: Though transplant guidelines recommend exercising caution when considering donor organs that may be infected or colonized with multidrug-resistant organisms (MDROs), the true impact of…
2019 American Transplant Congress
Comparison of Proton Pump Inhibitors versus Histamine-2-Receptor Antagonists on Clostridium difficile Rates in Liver Transplant Recipients
S. Wiehe, K. Roach, A. Qamar
Lahey Hospital and Medical Center, Burlington, MA
*Purpose: To determine if there is a difference in 90 day Clostridium difficile infection (CDI) rates before and after the stress ulcer prophylaxis (SUP) protocol…
2019 American Transplant Congress
Cholecystitis in High-Acuity Patients Undergoing Liver Transplantation: A Five-Year Analysis of Incidence, Causes and Impact
D. S. Graham, T. Ito, M. M. Lu, J. DiNorcia, V. G. Agopian, H. Yersiz, D. G. Farmer, R. W. Busuttil, F. M. Kaldas
Dumont-UCLA Liver Transplant Center, Department of Surgery, UCLA School of Medicine, Los Angeles, CA
*Purpose: While the incidence of gallbladder pathology is well described in the general population, there is almost no data on cholecystitis in liver transplant candidates…
2019 American Transplant Congress
Hypothermic Machine Perfusion Protects Donation After Cardiac Deathliver Graft Through Gstm1-mediated Cytochrome P450 Exogenous Substance Metabolism Pathway
W. Liang, S. Ye, Z. Zhong, Q. Hu, Y. Wang, Q. Ye
Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases, Wuhan, China
*Purpose: Donation after cardiac death (DCD) is the mainly resource to relieve organ-transplantation shortage. Our previous research have confirmed that the function of DCD liver…
2019 American Transplant Congress
Transfer of Healthy Mitochondria in Established Ischemic Injury Reduces Progression to Interstitial Fibrosis and Tubular Atrophy
A. Bajwa¹, V. Bontha¹, D. Maluf¹, J. Eason², V. Mas³
¹UTHSC, Memphis, TN, ²Director of Transplant Institute, Memphis, TN, ³Director of Transplant Research Institute, Memphis, TN
*Purpose: Ischemia induces altered bioenergetics with increased mitochondrial swelling and reactive oxygen species (ROS) and ultimately degradation of cellular function. Therapeutic interventions that target to…
2019 American Transplant Congress
Characterization of Circulating T-cell Specific Exosomes during Acute Rejection in Murine Heart Transplantation Model
R. Hu¹, V. Korutla¹, L. Korutla¹, S. Rostami¹, A. Habertheuer¹, S. Addya², J. Harmon¹, P. Zielinski¹, S. Reddy¹, A. Freas¹, C. Ram¹, A. Naji¹, P. Vallabhajosyula¹
¹Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, ²Thomas Jefferson University, Philadelphia, PA
*Purpose: Exosomes are nanoparticles (30-200nm) released by many cell types. They carry nucleic acid and proteins that may reflect conditional changes in their tissue counterparts.…
2019 American Transplant Congress
Use of TruGraf Serial Testing for Confirming Stability in Kidney Transplant Patients with Stable Renal Function
V. Peddi¹, C. Schieve², S. Rose², M. First²
¹California Pacific Med Ctr, San Francisco, CA, ²Transplant Genomics Inc, Mansfield, MA
*Purpose: The objectives of this study were to model serial TruGraf testing in stable kidney transplant recipients and to demonstrate the potential clinical utility of…
2019 American Transplant Congress
Need of a New Formula to Estimate Creatinine Clearance in Immediate Post Kidney Transplant Period with Functioning Allograft
A. B. Jain¹, U. Farooq², A. Brooks¹, T. Dohi¹, F. Butt¹, Z. Kadry¹
¹Surgery ( Transplant), Penn State Milton Hershey Medical Center, Hershey 17033, PA, ²Medicine( Neprhology), Penn State Milton Hershey Medical Center, Hershey, PA
*Purpose: Introduction: Post kidney transplant (KTx), with functioning renal allograft, serum creatinine continues to decrease at a variable rate until it stabilizes after a few…
2019 American Transplant Congress
Could Intravenous Iron Strengthen The Chances Of Heart Transplantation For Patients With Left Ventricular Assist Devices?
A. Mardis¹, C. Mardis², J. Barham³, A. Poole³, S. Branham³, R. Napier⁴, J. Martin³, P. McCann⁴
¹Department of Pharmacy, Palmetto Health, Columbia, SC, ²Clinical Pharmacy and Outcomes Sciences, University of South Carolina, Columbia, SC, ³Cardiothoracic Surgery, Palmetto Health, Columbia, SC, ⁴Cardiology, Palmetto Health, Columbia, SC
*Purpose: Iron deficiency anemia (IDA) is prevalent in patients supported by left ventricular assist devices (LVADs), is associated with functional limitations, and often warrants blood…
2019 American Transplant Congress
Immune Privilege May Predispose Patients after Orthotopic Heart Transplantation to Develop Recipient to Donor Atrial Connections Associated with Atrial Arrhythmias
B. Herweg¹, M. Nellaiyappan¹, T. Tran¹, G. Mabry¹, K. Weston¹, H. J. Eisen², M. Weston³
¹Cardiovascular Sciences, University of South Florida Morsani College of Medicine, Tampa, FL, ²Heart and Vascular Institute, Pennsylvania State University, Hershey, PA, ³Tampa General Hospital, Tampa, FL
*Purpose: The formation of functional electrical inter-atrial connections (IAC) between recipient and donor atria after orthotopic heart transplantation (OHT) is intriguing and its mechanism is…