2019 American Transplant Congress
Late Acute Rejection Increases Risk Of Graft Failure In Ldlt Recipients: Data From The A2all Cohort
University of California, San Francisco, San Francisco, CA
*Purpose: Late acute rejection (LAR) is defined as an initial episode of acute rejection occurring >6 months after transplantation. LAR in liver transplantation (LT) is…2019 American Transplant Congress
One Study: A Consortium Model of Clinical Trials Optimized for Comparing New Immune Therapies via Centralized Immune Monitoring
*Purpose: Immune regulatory cell subpopulations can potentially control immune responses to allow immunosuppression (IS) drug minimization. In the ONE Study, an EU FP7-funded research group…2019 American Transplant Congress
Prevention of Graft Ischemia-Reperfusion Injury in Ischemia-Free Liver Transplantation
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: Graft ischemia-reperfusion injury (IRI) is an inevitable event in organ transplantation, which often leads to a number of complications and even patient deaths. We…2019 American Transplant Congress
Does the Type of Pre-Heart Transplant Desensitization Therapy Affect 5-Year Post-Transplant Outcomes?
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: As many patients with severe heart disease require mechanical circulatory support (MCS), the number of sensitized patients developing circulating antibodies continues to rise. In…2019 American Transplant Congress
Impact of Steroid-Free Protocol on Incidence of Posttransplantation Diabetes Mellitus: A Prospective, Randomized, Multicenter, Open-Label, Controlled Trial in Renal Transplant Recipients
*Purpose: Comparison of two immunosuppressive protocols, steroid-free with antithymocyte globulin (ATG) induction, and steroid containing with basiliximab induction, regarding the incidence of PTDM, one year…2019 American Transplant Congress
Preemptive Kidney Transplantation: Is There a Role for ABO Incompatible Transplantation?
1University of Alabama at Birmingham, Birmingham, AL, 2University of Pennsylvania, Philadelphia, PA
*Purpose: Barriers to kidney transplantation (KT) exist, including ABO incompatibility (ABOi) between potential living kidney donors and transplant candidates. Incompatible pairs can undergo desensitization or…2019 American Transplant Congress
Utilization of DCD Donors >50 Years Old for Liver Transplantation
Arizona Transplant Associates, PC, Phoenix, AZ
*Purpose: End stage liver disease is becoming more prevalent in the United States with approximately 4.9 million adults carrying the diagnosis. It is estimated that…2019 American Transplant Congress
Undernutrition and Leptin Deficiency Modulates T Cell Immunity in Transplantation
1Pediatrics, Duke University, Durham, NC, 2Surgery, Duke University, Durham, NC
*Purpose: We have previously shown an association between undernutrition and the development of viremia in transplanted children. While undernutrition is associated with impaired T cell…2019 American Transplant Congress
Anti-Donor M H C Class I I Alloantibody Induce Glomerular Injury in Mouse Renal Allografts Subjected to Prolonged Cold Ischemia
Inflammation and Immunity, Cleveland Clinic, Cleveland, OH
*Purpose: Prolonged cold ischemia storage (CIS) of donor transplants is a major risk factor for acute and chronic graft tissue injury.The goal of this study…2019 American Transplant Congress
The Burden of Recipient Driving Distance and Post Lung Transplant Outcomes: A National Cohort Study
Cleveland Clinic, Cleveland, OH
*Purpose: There are only 75 lung transplant centers in the United States, which leads to a spectrum of travel burdens among patients in order to…
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