ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Early Association of Low Doses of Tacrolimus and a mTOR Inhibitor in BK Polyomavirus Infection in Kidney Transplant Recipients

    V. Lopez,1 T. Vazquez,1 C. Jironda,1 M. Cabello,1 E. Sola,1 M. Leon,2 E. Marques,1 D. Hernandez.1

    1Nephrology, Hospital Regional Malaga, Malaga, Spain; 2Pathology, Hospital Regional Malaga, Malaga, Spain.

    Introduction: BK polyomavirus (BKV) replication can be detected in up to 60% of kidney transplant recipients, with an incidence of nephropathy of 5-10%, leading to…
  • 2018 American Transplant Congress

    A Six-Month, Prospective, Single-Center, Pilot Study to Determine the Pharmacokinetics and Effectiveness of Immunosuppressant Regimens in Liver Transplantation Patients Receiving Twice-Daily Tacrolimus and Everolimus (TAC + EVR BID) Regimen Converted to Once-Daily Tacrolimus and Everolimus (TAC + EVR QD) Regimen – A Priliminary Report

    T-.H. Wu, C-.H. Cheng, Y-.C. Wang, C-.F. Lee, T-.J. Wu, H. Chou, K-.M. Chan, W-.C. Lee.

    Division of Liver and Transplantation Surgery, Chang-Gung Memorial Hospital, Chang-Gung University College of Medicine, Taoyuan, Taiwan.

    Adherence to immunosuppressant regimen is crucial for graft survival and usually inversely related to the dose frequency. Similar efficacy and safety profile has been approved…
  • 2018 American Transplant Congress

    Outcomes of Liver Transplantation for Hepatic Epithelioid Hemangioendothelioma in the U.S. (2002-2015)

    T. Bittermann,1 S. Prenner,1 P. Abt,2 D. Goldberg.1,3

    1Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA; 2Division of Transplant Surgery, University of Pennsylvania, Philadelphia, PA; 3Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA.

    Hepatic epithelioid hemangioendothelioma (HEHE) is a rare, malignant vascular tumor of the liver with high mortality if left untreated. Liver transplantation (LT) is potentially curative,…
  • 2018 American Transplant Congress

    The Outcomes of Candidates Underwent Liver Transplantaion with Portopulmonary Hypertension: A Meta-Analysis

    R. Deng, B. Huang, Y. Shi, Y. Ma.

    Organ Transplantation Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

    Background: Portopulmonary hypertension(PPH) was once regarded as a contraindicaton in liver transplantation(LT).However,growing evidence indicated that PPH patients underwent LT may show similar outcomes compared to…
  • 2018 American Transplant Congress

    Mycoplasma hominis Infection in Lung Transplant Recipients: A Retrospective Case Series

    J. Wright,1,2 N. Law,4 M. Murray, S. Poutanen,1,2 S. Husain,1 S. Keshavjee,1 L. Singer,1 A. Humar,1 D. Kumar.1

    1UHN, Toronto, ON, Canada; 2University of Toronto, Toronto, ON, Canada; 3UC-San Diego, San Diego.

    Background: Mycoplasma hominis is increasingly recognized as a respiratory pathogen causing invasive disease in solid organ transplant (SOT) recipients. We reviewed the clinical characteristics, management…
  • 2018 American Transplant Congress

    Age-Specific Effects of Tacrolimus Are Associated to Specific Changes of T Cell Metabolism

    Y. Nian, T. Heinbokel, K. Minami, R. Abdi, A. Elkhal, S. Tullius.

    Transplant Surgery Research Lab, Brigham and Women's Hospital, Boston.

    Background: Energy metabolism of immune cells has been identified as critical in driving alloimmunity. While metabolic capacities change with aging, aspects linking age, immunosuppression, and…
  • 2018 American Transplant Congress

    Preparation for Transfer to Adult Kidney Transplant Care: Impacts of Providing Written Guidance

    H. Stephens,1 M. Clementi,1 A. Al-Uzri, M. Wright,4 S. Iragorri,2 D. Rozansky,2 R. Jenkins,2 J. Wade,3 K. Richardson,5 K. Freeman.1

    1Institute on Development & Disability, Department of Pediatrics, Oregon Health & Science University, Portland, OR; 2Department of Pediatrics, Oregon Health & Science University, Portland, OR.

    Objective: Survey youth and parents in a pediatric kidney transplant clinic with the following aims: 1) Compare pre- and post-intervention experiences with the transition process;…
  • 2018 American Transplant Congress

    Cytomegalovirus Infection in Pediatric Solid Organ Transplant Recipients and Role of Prophylaxis

    G. Nance,1 A. Serluco,1 S. Deshpande,2,1 R. Garro,3,1 R. George,3,1 M. Kelleman,3 R. Liverman.1

    1Children's Healthcare of Atlanta, Atlanta, GA; 2Sibley Heart Center Cardiology, Atlanta, GA; 3Emory University, Atlanta, GA.

    Objectives: Cytomegalovirus (CMV) is an opportunistic infection that can lead to significant complications post-transplant. Purpose of this study was to evaluate the use of valganciclovir…
  • 2018 American Transplant Congress

    Risk Factors and Outcomes with Carbapenem-Resistant Enterobacteriaceae Bloodstream Infections among Solid Organ Transplant Recipients

    J. Anesi,1 E. Blumberg,1 E. Lautenbach,1 J. Omorogbe,1 P. Tolomeo,1 P. Tamma,2 K. Thom,3 K. Alby,1 W. Bilker,1 A. Werzen,3 K. Nemati,2 J. Han.1

    1University of Pennsylvania, Philadelphia, PA; 2Johns Hopkins University, Baltimore, MD; 3University of Maryland, Baltimore, MD.

    Objective: Solid organ transplant recipients (SOTR) have been disproportionately burdened by the emergence of multidrug-resistant bacteria, including carbapenem-resistant Enterobacteriaceae (CRE). We determined risk factors for…
  • 2018 American Transplant Congress

    A National Survey of Valganciclovir Dosing Strategies in Pediatric Solid Organ Transplant Recipients

    S. Shaikh, N. Panek, J. Park.

    MedStar Georgetown University Hospital, Washington DC; Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago; Michigan Medicine, Ann Arbor.

    Objective: The FDA-approved pediatric indication of valganciclovir (VGCV) is limited to cytomegalovirus (CMV) prophylaxis in heart and kidney transplants. The recommended regimen is a daily…
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