2018 American Transplant Congress
Enhancement of Muscle Regeneration and Function via Transplantation of Human Dystrophin Expressing Chimeric Cells as a Novel Myoblast Stem-Cell Based Therapy
PURPOSE: Allogeneic myogenic stem cell transplantation aims to restore muscle tissue after traumatic loss or to treat muscular dystrophies. Limited engraftment due to allogeneic rejection…2018 American Transplant Congress
Closing Pandora's Box: An Evidence Based Approach to Opioid-Tolerant Patients Following Transplantation. The Case for IV Methadone
Department of Surgery, Beaumont Health, Royal Oak, MI.
The purpose of this study is to explore the use of parenteral methadone in opioid-tolerant patients who are status-post transplantation. As an alternative to traditional…2018 American Transplant Congress
Depressive Symptoms, Medication Nonadherence, and Clinical Outcomes Following Lung Transplantation
Background:Elevated depressive symptoms have been associated with worse clinical outcomes following lung transplantation, including mortality. Few studies, however, have examined the mechanisms or clinical correlates…2018 American Transplant Congress
Liver Preservation with Machine Perfusion and a New Human-Derived Hemoglobin-Based Oxygen Carrier Solution (HDHBOC)
1VirTech Bio, Inc, Natick, MA; 2University of Pittsburgh, Pittsburgh, PA.
Introduction: Machine perfusion (MP) is becoming the new standard for liver preservation following the successful implementation of devices for kidney and lung preservation ex-vivo. Liver…2018 American Transplant Congress
Allogeneic Mesenchymal Stem Cells as Induction Therapy Are Safe and Feasible in Renal Allografts: Pilot Results of a Multicenter Randomized Controlled Trial
Background: Delayed graft function (DGF) and acute rejection lead to adverse effects on graft outcomes. Optimal induction intervention should include both renal structure injury repair…2018 American Transplant Congress
NFkB Inhibitor Improves Glycemic Control after Syngeneic Islet Transplantation by Suppression of Proinflammatory and Apoptotic Gene Expression in a Cerulein-Induced Pancreatitis Model
Total pancreatectomy with islet autotransplantation (TPIAT) is an effective treatment for refractory chronic pancreatitis. Repeated or continuous pancreatitis attack leads islet damage beyond inflamed exocrine…2018 American Transplant Congress
Two Years of the HOPE Act
1United Network for Organ Sharing, Richmond, VA; 2Johns Hopkins University, Baltimore, MD.
The HOPE Act allows research on transplantation of organs from HIV+ donors into patients infected with HIV prior to transplantation. There are 42 kidney and…2018 American Transplant Congress
Potential Living Donors Identified through Social Media
Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD.
Purpose: We previously described a smartphone application that harnesses social media to increase potential living donors among kidney and liver transplant candidates. We compared potential…2018 American Transplant Congress
Treatment of Post Transplant Hepatitis C (HCV) with Direct-Acting Antiviral (DAA) Agents May Improve Liver Function but Does Not Lead to an Increase in Liver Rejection
Surgery, Hartford Hospital, Hartford, CT.
Previous studies have suggested that with the use of with (DAA) agents to treat post transplant (HCV), there has been an increased incidence of liver…2018 American Transplant Congress
Survival Rates of Patients with Previous Cardiac Surgery Undergoing Lung Transplant
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH.
Background: Severe heart diseases are traditionally considered a contraindication for Lung transplantation (LTx). There are suggestions that patients with severe heart diseases undergoing LTx will…
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