2018 American Transplant Congress
To Score a Pancreas, Stars Must Be Aligned
Excellent medical care and readily accessible insulin preparations serve to require a very high quality of deceased donor pancreas organs accepted for transplantation. Improving, prevailing…2018 American Transplant Congress
Innovative Strategies to Accommodate Increased Patient Volume in an Outpatient Transplant Infusion Center
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA.
Purpose: To accommodate the increasing volume of patients scheduled for infusions at the Comprehensive Transplant Center(CTC) Infusion suite. It began as a two chair unit…2018 American Transplant Congress
Human CD8+CD28– Ts Cells Expanded by Common Gamma Chain (γc) Cytokines Keep Steady Allospecific Suppressive Capacity In Vivo
Background: CD8+CD28- T suppressor (Ts) cells were recently reported to play a critical role in transplant tolerance, harnessing the potential for clinical use in transplantation.…2018 American Transplant Congress
Standard Induction Immunosuppression Interferes with the Role of Vascularized Bone Marrow in Vascularized Composite Allograft Protection
Department of Surgery, University of Maryland School of Medicine, Baltimore, MD.
Purpose: Clinical induction therapies have been demonstrated to interfere with the development of immunologic tolerance in experimental models. Vascularized bone marrow (VBM) has been demonstrated…2018 American Transplant Congress
In Vitro α-Galactosylceramide Stimulation Expands CD4+CD25+Foxp3− Regulatory T Cell Precursors in Murine Thymocytes
Background: We previously established mixed chimerism after invariant natural killer T-cell stimulation by administration of liposomal α-galactosylceramide (lipo-αGC) and costimulatory blockade, leading to regulatory T…2018 American Transplant Congress
Application of RNA-Seq Derived Diagnostic Algorithms of T-Cell Mediated Kidney Rejection (TCMR) to DNA Microarray-Based Gene Expression Datasets
Recent years have seen the development of DNA microarray based tools for the diagnosis of TCMR using fresh frozen tissue. This study has accomplished the…2018 American Transplant Congress
Assessing the Impact of Flow in Hypothermic Machine Perfusion on Human Venous Endothelium Using a Novel Ex Vivo Model
BACKGROUNDHypothermic machine perfusion (HMP) involves dynamic flow of chilled preservation fluid through an allograft's vasculature. This study describes a simple, reproducible, human model that allows…2018 American Transplant Congress
The Combination of pAMR and Circulating Donor-Specific Antibodies is Even More Associated with Cardiac Allograft Vasculopathy after Heart Transplant
Cedars Sinai Medical Center, Los Angeles.
Purpose: Several reports have correlated the development of donor-specific antibody (DSA) to the development of cardiac allograft vasculopathy (CAV) after heart transplantation (HTx). Interestingly, patients…2018 American Transplant Congress
Air Pollution Can Support the Development of Cardiac Allograft Vasculopathy
Purpose:Cardiac allograft vasculopathy (CAV) remains one of most important factors leading to graft dysfunction and mortality after heart transplantation (HTx). Thus, the identification of risk…2018 American Transplant Congress
Left Ventricular Assist Devices Complicated by Gastrointestinal Bleeding and Outcomes on Transplant
Internal Medicine, Cardiac Surgery, Cardiology, Henry Ford Hospital, Detroit.
Left Ventricular Assist Devices (LVAD) are becoming the standard of care in advanced heart failure patients. However, despite ongoing advances in this technology, there remains…
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