2017 American Transplant Congress
Post Transplant Outcomes in Hepatitis C Positive Patients.
Montefiore Medical Center, Bronx
Hepatitis C (HCV) is associated with increased morbidity and mortality after kidney transplant (KTx). We aimed to assess outcomes of HCV positive patients at our…2017 American Transplant Congress
Which Is More Nephrotoxic to Kidney Transplants: BK Nephropathy or Rejection?
University of Wisconsin, Madison
The relative nephrotoxicity of BK nephropathy (BKN) vs acute rejection is unknown. This is an important question, since clinicians often must choose between reducing immunosuppression…2017 American Transplant Congress
Impact of Pre-Donation eGFR on Long-Term Post-Donation eGFR in Younger Living Kidney Donors.
Objective: Most transplant centers require living kidney donors (LKDs) to have a minimum estimated glomerular filtration rate (eGFR) to ensure adequate kidney reserve to withstand…2017 American Transplant Congress
Renal Function Outcomes of Hypertensive Living Kidney Donors (HLD) and Recipients of HLD Kidneys: Results of a Case-Control Study.
1Nephrology, Ohio State, Columbus, OH; 2Transplant, Ohio State, Columbus, OH
As the shortage of suitable deceased and living kidney donors (LD) persists, medically complex LD, including those with hypertension (HTN), are being considered for donation…2017 American Transplant Congress
Human Organs Allocated for Research – Maximising Use of a Precious Resource Using a New Ex Vivo Model of Reperfusion Injury.
Imperial College, London, United Kingdom
Purpose: A greater interest in machine perfusion strategies for all solid organs has led to a substantial increase in the allocation and utilisation of human…2017 American Transplant Congress
Kinetics of Cytomegalovirus (CMV) DNAemia in CMV Mismatch Solid Organ Transplant Patients with Primary CMV Infection.
Medicine, University of Alberta, Edmonton, Canada
Despite antiviral prophylaxis, CMV infection is common in CMV mismatch (D+/R-) patients. We aimed to study the kinetics of CMV viral load in primary CMV…2017 American Transplant Congress
Pharmakokinetics of Daclatasvir, Sofosbuvir and GS-331007 in a Prospective Cohort of HCV Positive Kidney Transplant Recipients.
BackgroundLimited data exist on the pharmacokinetic (PK) profile of novel direct acting antivirals in kidney transplant recipients (KTR). Here we report the PK of combinated…2017 American Transplant Congress
Rates of CMV Infection in Kidney Transplant Recipients Who Received Subtherapeutic Valganciclovir Prophylaxis.
Purpose: The aim of this study was to compare the rate of cytomegalovirus (CMV) infection after kidney transplantation in high and intermediate risk patients who…2017 American Transplant Congress
Inhibition of Heat Shock Protein 90 Suppresses the Expression of MHC Class I Molecules, but Not MHC Class II Molecules, on Endothelial Cells in Allografts.
Urology, Sapporo Medical University, Sapporo, Japan
Purpose: Heat shock protein 90 (HSP90) is a ubiquitously expressed molecular chaperone that is associated with the correct activation of client proteins. Important roles of…2017 American Transplant Congress
mTORC1 and 2 Regulate Dendritic Cell (DC) Metabolism and Allostimulatory Function of Donor DCs in Skin Transplantation.
Background/Hypothesis: The mechanistic target of rapamycin (mTOR) is a kinase that functions in two complexes: rapamycin (RAPA)-sensitive mTORC1 and RAPA-insensitive mTORC2. These complexes play critical…
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