ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Increased Gene Expression of TGF-β in Peripheral Blood Mononuclear Cells from Renal Transplant Patients with Polyomavirus BK Viremi.

    W. Yin.1,2

    1Surgery, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Dalin, Taiwan; 2School of Medicine, Tzu Chi University, Hualien, Taiwan

    We aimed to investigate the roles of cytokines during polyomavirus BK (BKV) reactivation in renal transplant patients. Forty-eight renal allograft recipients were enrolled in this…
  • 2017 American Transplant Congress

    Reasons for Ineligibility for Kidney Donation by Race: Gap for Blacks Represented by Modifiable Factors, However Are Big Hurdles to Overcome.

    D. Simpson,1 M. Levine,1 S. Amaral.2

    1Hospital of the University of Pennsylvania, Philadelphia, PA; 2Children's Hospital of Philadelphia, Philadelphia, PA

    Background: It is well-recognized that blacks are much less likely to receive living donor kidney transplants. Improved characterization of the reasons for differences in living…
  • 2017 American Transplant Congress

    Integration of Kidney-Exchange, (Un)Specified Living Donor Transplantation, ABO Incompatible and Desensitisation Programs in a Computerized Allocation Program: A Simulation.

    M. de Klerk,1 J. Kal,1 S. Middel,1 J. van de Wetering,1 M. Kho,1 M. Betjes,1 W. Zuidema,1 D. Roelen,3 K. Glorie,2 J. Roodnat.1

    1Dept of Internal Medicine, Erasmus MC, Rotterdam, Netherlands; 2Erasmus Q-Intelligence, Erasmus University Rotterdam, Rotterdam, Netherlands; 3Dept of Immunology, LUMC, Leiden, Netherlands

    Introduction: Our national kidney-exchange allocation program is established in 2004. Though kidney-exchange is intertwined with (un)specified donation and domino-paired procedures, the latter still operates by…
  • 2017 American Transplant Congress

    Impact of Donor Asystole in Intestine Transplant.

    J. Schroering, C. Kubal, R. Mangus.

    Surgery, Indiana University, Indianapolis, IN

    Intestine transplantation has a high risk of post-transplant complications. For this reason, many intestine transplant centers are conservative in their choice of deceased donors, using…
  • 2017 American Transplant Congress

    Impact of Timeliness of Assessment of Positive Cytomegalovirus Polymerase Chain Reaction Results in Abdominal Organ Transplant Recipients.

    K. Roach, H. Triemer, M. Hurtik, A. Mehta.

    Emory University Hospital, Atlanta, GA

    Purpose: The purpose of this study was to evaluate the timeliness of assessment of positive cytomegalovirus (CMV) polymerase chain reaction (PCR) results. This study served…
  • 2017 American Transplant Congress

    The Evolution of Hepatitis B Surface Antibody (Anti-HBs) Titer of the Kidney Transplant Recipients: A 5-Year Experience Guideline for the Optimal Maintaining Immunization.

    W. Chancharoenthana, A. Leelahavanichkul, S. Wattanatorn, Y. Avihingsanon, K. Praditpornsilpa, N. Townamchai.

    Division of Nephrology, Department of Medicine, Chulalongkorn University, Bangkok, Thailand

    Background: Immunization against hepatitis B virus (HBV) in kidney transplantation (KT) recipients is recommended as KDIGO guideline. Although hepatitis B surface antibody (anti-HBs) titer of…
  • 2017 American Transplant Congress

    Evaluation of Function and TCR signaling Profile of CD57+ T Cells in Allo-Specific Immunity.

    H. Xu,1 T. Brennan,1 Q. Li,2 A. Kirk.1

    1Department of Surgery, Duke University School of Medicine, Durham, NC; 2Department of Immunology, Duke University School of Medicine, Durham, NC

    Our studies have showed that CD57+ cells are resistant to B7 costimulation blockade (CoB). We hypothesize that CD57+ cells are highly sensitive to T cell…
  • 2017 American Transplant Congress

    RAS Inhibition Attenuates Urine Angiotensin II-Regulated Proteins Associated with Interstitial Fibrosis and Tubular Atrophy in Kidney Transplant Recipients.

    Z. Mohammed-Ali,1 S. Reid,3 P. Yip,1 H. Cardinal,2 M.-J. Hébert,2 Y. Li,4 S. Kim,1,3,4 A. Konvalinka.1,3

    1University Health Network, Toronto, ON, Canada; 2Centre de Recherche du Centre Hospitalier de l'Université de Montréal - CRCHUM, Montréal, QC, Canada; 3Institute of Medical Science, University of Toronto, Toronto, ON, Canada; 4Institute of Health Policy, University of Toronto, Toronto, ON, Canada

    Angiotensin-II (AngII), the main effector of the renin-angiotensin system (RAS), can lead to interstitial fibrosis/ tubular atrophy (IFTA) in kidney transplant recipients, mainly through AT-1R…
  • 2017 American Transplant Congress

    Modification of Human Endothelial Cells by CRISPR/Cas9-Mediated Ablation of Class I and II Major Histocompatibility Complex Antigen Expression.

    J. Merola, C. Anderson, H. Xu, T. Manes, J. Pober.

    Yale School of Medicine, New Haven, CT

    Human endothelial cells (ECs) derived from cord blood progenitors have significant replicative potential and are thus well suited for use in tissue engineering of vascularized…
  • 2017 American Transplant Congress

    Memory T Cells Are Decreased in Transplant Recipients Deficient in miR-182.

    V. Kaul, L. Wei, X. Qu, O. Martinez, S. Krams.

    Transplant Immunology Lab/Division of Abdominal Transplant, Stanford University, Stanford

    MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate the post-transcriptional expression of target genes. There is ample evidence that miRNAs are involved in the…
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