2017 American Transplant Congress
Associations Between Provision of Transplant Pharmacy Services and Center-Level Patient and Graft Outcomes in U.S. Adult Kidney Transplant Programs.
As a follow up to a U.S. transplant pharmacist workforce survey in 2013-14 (AJT 2015;15:2683-90), we assessed associations between transplant pharmacist involvement and daily activities…2017 American Transplant Congress
Reproducibility of the Cobas CMV Test (cobas CMV) and Clinical Concordance with the Cobas Ampliprep / Cobas TaqMan CMV Test (CAP/CTM CMV).
cobas CMV is a new, automated, high-throughput assay for use on the cobas 6800/8800 systems that quantifies CMV DNA in EDTA-plasma. It can be run…2017 American Transplant Congress
Nonmelanoma Skin Cancer Rates Are Not Affected by Chronic HIV(+) or HCV(+) Infection in Organ Transplant Recipients.
Dermatology, Drexel, Philadelphia
Purpose: HIV and HCV are two immune dysregulatory processes that may exacerbate the risk of nonmelanoma skin cancer (NMSC) in organ transplant recipients (OTR), a…2017 American Transplant Congress
Patients with Renal Failure Have a pERK-Dependent Defective TCR-Mediated Activation of CD4+ T Cells.
Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands
Introduction Patients with end-stage renal disease (ESRD) have an impaired immune response with a prematurely aged T cell system. Mitogen-activated protein kinases (MAPKs) including extracellular…2017 American Transplant Congress
Kidney Recipients with 10 Year Belatacept-Treatment Display an Altered T Cell Subset Composition and Low Plasma Cytokine Levels Compared to Matched Patients with CNI-Based Immunosuppression.
Introduction/BackgroundMore than 10 years ago, Belatacept (Bela)-based immunosuppression was investigated in the BENEFIT trial of kidney transplantation (KTx) compared to CNI-based immunosuppression. Bela inhibits T…2017 American Transplant Congress
SIRPα+ DCs and the Time-Dependent CD4+CD8+ Double Positive T Cell Infiltration in Accepted Renal Allografts.
IntroductionIn 2015 Overgaard and colleagues proposed that double positive T (DPT) cells, usually unique to the thymus, represent more than a developmental phase as extrathymic…2017 American Transplant Congress
Impact of Complement Component 3 Single Nuclear Polymorphisms on Renal Transplant Recipients with Antibody-Mediated Rejection.
Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
Impact of complement component 3 single nuclear polymorphisms on renal transplant recipients with antibody-mediated rejectionZijie Wang, Zhijian Han, Jun Tao, Ruoyun Tan, Min GuDepartment of…2017 American Transplant Congress
Donor-Derived Cell-Free DNA Is a Dynamic Biomarker of Active Rejection in Kidney Allografts.
Purpose: Donor-derived cell-free DNA (dd-cfDNA) has shown promise as a biomarker in identification of allograft rejection. Here we report on the changes in dd-cfDNA prior…2017 American Transplant Congress
Incidence and Clinical Outcomes of Mycobacterium tuberculosis Infections Following Renal Transplantation in Endemic Country.
Background: Most cases of Tuberculosis (TB) in solid organ transplant recipients are caused by reactivation of a latent infection after initiation of immunosuppressive therapy. This…2017 American Transplant Congress
Outcomes Following Reduction of Immunosuppression in Solid Organ Transplant Recipients with Cryptococcosis.
Background: Cryptococcosis (crypto) is the third most common fungal infection in solid organ transplant (SOT) recipients. Although reduction of immunosuppression (IS) may improve patient outcomes…
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