2017 American Transplant Congress
Simultaneous or Sequential Heart-Liver Transplantation Confer Superior Survival in Patients with Listed for Heart-Liver Transplantation: A National Analysis.
1Duke School of Medicine, Durham, NC; 2Dept of Surgery, Duke University Medical Center, Durham, NC
Background: Simultaneous heart-liver transplantation (TXP), for patients with combined heart and liver failure, confers survival benefit over remaining on the waitlist. Whether heart TXP followed…2017 American Transplant Congress
Assessment of the Risk Index for Living Donor Kidney Transplantation (LKDPI) in a European Cohort.
Nephrology, Charité Universitaetsmedizin, Berlin, Germany
Introduction: Recently, a risk index for living donor kidney transplantation (LKDPI) was proposed (Massie et al. AJT 2016) to compare living donor kidneys (LDK) to…2017 American Transplant Congress
Impact of Antihypertensive (AHT) Choice and Advagraf® Dose on Immunologic Events in Renal Allografts 24 Months Post-Transplantation (Tx).
Renal allograft inflammation may be modulated by ACEi- or ARB-type AHTs (renin-angiotensin system (RAS)-targeting drugs that may inhibit calcineurin) or by optimizing tacrolimus (TAC) exposure.…2017 American Transplant Congress
Pre-Transplant Evaluation of KSORTSM to Assess Risk for Rejection in Highly Sensitized Patients.
Study purpose: To investigate the kSORTSM molecular expression assay for immune risk assessment in renal transplant (tx) recipients prior to tx for correlation of pre-tx…2017 American Transplant Congress
Desensitization versus Deceased Donor Kidney Transplantation: What to Choose When Both Become Available?
1UCSF, San Francisco; 2Johns Hopkins, Baltimore; 3NYU, New York
Kidney allocation system changes have improved deceased donor kidney transplant (DDKT) access for highly sensitized patients. For patients with a willing live donor but requiring…2017 American Transplant Congress
Is Deceased Donor Kidney Transplantation (DDTX) Justified in Patients with More Than 10 Years of Pre-TX Dialysis Exposure?
Background: The new kidney allocation system (KAS) led to an increase in DDTX among patients with ≥10 years of pre-TX dialysis exposure. We aimed to…2017 American Transplant Congress
Immunosuppression and Graft Rejection in Living-Related HLA-Identical Renal Transplantation.
Purpose: We aimed to describe the immunosuppressive regimens and graft rejection rates in living-related HLA-identical (LR HLAid) renal transplantation.Methods: We performed a retrospective multicenter analysis…2017 American Transplant Congress
A Low-Dose Anti-Hepatitis B Immunoglobulin Regimen for Prophylaxis of Hepatitis B Recurrence.
Liver and Transplantation Surgery, Chang-Gung Memorial Hospital, Taoyuan, Taiwan
Background: Hepatitis B virus (HBV)-related liver disease is the major indication of liver transplantation in Asian countries. Combination of anti-hepatitis B immunoglobulin (HBIg) and anti-viral…2017 American Transplant Congress
Reduced Conversion from IgM Anti-HLA-DSA to IgG Anti-HLA-DSA in Belatacept-Treated vs. Cyclosporine-Treated Patients in BENEFIT and BENEFIT-EXT Trials.
Post-transplant, up to 50% of recipients develop IgM DSA. Half of these patients go on to develop IgG DSA. Importantly, patients that progress to IgG…2017 American Transplant Congress
High CTLA-4 Expression and Diminished FOXO3 Expression Underlie Differential CD28 Signaling on Human Memory Th17 Cells.
Pathogen primed memory T cells can cross-react with allogeneic antigen and mediate graft rejection, a process termed allogeneic heterologous immunity. Th17 cells are pro-inflammatory CD4+…
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