ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    BK Polyomavirus-Specific 9mer T-Cell Responses Predict Control of Viremia in Kidney Transplant Recipients: First Report from the Swiss Transplant Cohort Study.

    H. Hirsch,1 C. Leboeuf,1 S. Wilk,1 R. Achermann,2 I. Binet,3 D. Golshayan,2 K. Hadaya,2 C. Hirzel,2 M. Hoffmann,2 U. Huynh-Do,2 M. Koller,2 O. Manuel,2 N. Mueller,2 T. Mueller,2 S. Schaub,2 C. Van Delden,2 F. Weissbach.1

    1University of Basel, Basel, Switzerland; 2Swiss Transplant Cohort Study, Basel, Switzerland; 3Cantonal Hospital St Gallen, St Gallen, Switzerland

    BK polyomavirus (BKPyV) causes premature kidney transplant (KT) failure in 1-15% of patients. Since antivirals are lacking, most programs screen KT patients for BKPyV viremia…
  • 2017 American Transplant Congress

    Effects of Liver Transplantation on Cardiac Function in Patients Transplanted for NASH Cirrhosis.

    H. Maddur, L. VanWagner, D. Gregory, B. Wodzinski, K. Maganti, M. Rinella.

    Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL

    Nonalcoholic Steatohepatitis (NASH) is independently associated with increased cardiovascular events after liver transplantation (LT). NASH is also associated with subclinical myocardial dysfunction in the general…
  • 2017 American Transplant Congress

    Expression of T-Cell Mediated Rejection (TCMR) Associated Genes in Native and Renal Allograft Renal Biopsies with Inflamed Scars (i-IFTA).

    Z. Lyu,1 L. Pang,1 G. Zeng,2 Y. Huang,2 P. Randhawa.2

    1Pathology & Nephrology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China; 2Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA

    The presence of i-IFTA in allograft kidney biopsies is a bad prognostic parameter. However, despite the presence of T-cell infiltrates in these lesions there is…
  • 2017 American Transplant Congress

    Ex-Situ Extended Limb Preservation: A Protocol for Porcine Limb Perfusion.

    E. Dalla Pozza,1 E. Duraes,1 M. Madajka,1 R. Frautschi,1 K. Cho,1 N. Dawlagala,1 V. Fahradyan,1 H. Shah,1 C. Cakmakoglu,1 C. Quintini,2 F. Papay,1 A. Rampazzo,1 B. Bassiri Gharb.1

    1Plastic Surgery, Cleveland Clinic, Cleveland, OH; 2General Surgery, Cleveland Clinic, Cleveland, OH

    Background: Ischemia and reperfusion injury remains a significant limiting factor for the success of vascularized composite allotransplantation. Compared to the cold storage of the procured…
  • 2017 American Transplant Congress

    Meta-Analysis of Clinical Significance of Complement Activating Anti-HLA DSA in Kidney Transplantation.

    A. Bouquegneau,1,2 C. Ulloa,1 O. Aubert,1 C. Loheac,1 D. Viglietti,1 J. Empana,1 P. Jabre,1 X. Jouven,1 C. Lefaucheur,1 A. Loupy.1

    1Paris Translational Research Center for Organ Transplantation, Paris, France; 2Department of Nephrology, Dialysis and Transplantation, Liège, Belgium

    Donor-specific anti-HLA antibodies (DSA) are currently recognized as the major limitation to access transplantation and the first cause of late transplant failures. The effect of…
  • 2017 American Transplant Congress

    Podocyte Participates in the ST2 Related Renal Fibrosis.

    Y. Kim,1 S. Yang,2,3 R. Cha,4 M.-Y. Yu,1 S. Lee,3 H. Lee,1 J. Lee,5 D. Kim,1,3 S. Kim,3 Y. Kim.1,2,3

    1Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; 2Seoul National University Biomedical Research Institute, Seoul, Republic of Korea; 3Kidney Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; 4Internal Medicine, National Medical Center, Seoul, Republic of Korea; 5Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea

    Objective Soluble ST2 (sST2) which is the receptor of IL-33 is involved in renal inflammation and it is also correlated with disease severity in chronic…
  • 2017 American Transplant Congress

    Assessment and Transplantation of Declined Human Kidneys Using Ex-Vivo Normothermic Kidney Perfusion.

    S. Hosgood,1 M. Hamed,1 A. Sawpaul,2 R. Figueiredo,2 K. Saeb-Parsy,1 C. Wilson,2 M. Nicholson.1

    1Department of Surgery, University of Cambridge, Cambridge, United Kingdom; 2Transplantation, Transplant Institute, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom

    PurposeThe aim of this study was to make more kidneys available for transplantation by using ex-vivo normothermic kidney perfusion (EVKP) technology to assess the quality…
  • 2017 American Transplant Congress

    Patient and Kidney Allograft Survival in Recipients with End Stage Renal Disease from Amyloidosis.

    M. Lim,1 D. Sawinski,1 J. Cohen,1,2 B. Weiss,3,4 J. Hogan,1,3 L. Dember.1,3

    1Renal, Electrolyte and Hypertension Division, Hospital of the University of Pennsylvania, Philadelphia, PA; 2Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; 3Penn Amyloidosis Program, Division of Hematology-Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA; 4Division of Hematology/Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA

    Background: Data on patient and graft outcomes of kidney transplant recipients with end stage renal disease (ESRD) from systemic amyloidosis is scarce. Methods: We performed…
  • 2017 American Transplant Congress

    Stable Deceased Donor Transplantation Rates Among Pediatric Candidates Post-KAS Implementation.

    B. Shelton,1 C. Ray,1 D. Sawinski,2 R. Reed,1 P. MacLennan,1 J. Locke.1

    1University of Alabama at Birmingham, Birmingham; 2University of Pennsylvania, Philadelphia

    Background: The Kidney Allocation System (KAS) was implemented in December 2014 and increased access to deceased donor kidney transplant (DDKT) for highly sensitized candidates. Concerns…
  • 2017 American Transplant Congress

    Living Kidney Donors: Battling High Attrition Rates During Evaluation Process.

    J. Verbesey, A. Bacigalupo, A. Gilbert, A. Li, C. Zuttermeister, M. Grafals, J. Moore, B. Javaid, P. Abrams, S. Ghasemian, M. Cooper.

    MedStar Georgetown Transplant Institute, Washington DC

    With an ever increasing kidney waiting list, a major goal is to expand living donor transplantation (LD). LD increases volume and provides higher quality, longer…
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