ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Incidence and Risk Factors for Cervical Dysplasia Associated to Human Papillomavirus Infection in Women with Kidney Transplant.

    I. Parra-Avila, J. Alberu, L. Marino-Vazquez, L. Morales-Buenrostro, R. Rosado-Canto.

    Department of Nephrology and Transplant, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

    Introduction: Women with kidney transplant (KT) have an increased risk for Human Papillomavirus (HPV) infection, which is related to cervical cancer, reaching an incidence of…
  • 2017 American Transplant Congress

    Role of Chemokines in Resolution of BK Virus-Associated Nephropathy and Chronicity of Pathology Changes in Kidney Transplant Recipients.

    J. Zuckerman, F. Palma Diaz, C. Magyar, B. Abdalla, E. Lum, S. Bunnapradist, T. Pham, G. Dannovitch, J. Veale, H. Gritsch, E. Reed, J. Schaenman.

    David Geffen School of Medicine at UCLA, Los Angeles, CA

    BK virus-associated nephropathy (BKN) remains the most common infectious cause of allograft loss after kidney transplantation. We previously demonstrated increased frequency of polyfunctional T cells…
  • 2017 American Transplant Congress

    Donor Kidney Volume Predicts One and Three Month eGFR in Live Donor Kidney Transplant Recipients.

    D. Al-Adra,1 M. Lambadaris,2 A. Barbas,1 Y. Li,2 N. Goldaracena,1 O. Famure,2 S. Kim,2 A. Ghanekar.1

    1Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada; 2Kidney Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada

    IntroductionThere has been increasing interest in non-immunological factors that may impact long-term graft survival after kidney transplantation. It is hypothesized that transplantation of larger nephron…
  • 2017 American Transplant Congress

    Impact of Early Allograft Dysfunction on Graft and Patient Outcomes After Liver Transplantation.

    Z. Guo, D. Zheng, X. He, G. Chen.

    The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    Objective: To evaluate the short-term and long-term impact of early allograft dysfunction (EAD) on graft and patient outcomes after liver transplantation.Background: EAD is one early…
  • 2017 American Transplant Congress

    Sequential Monitoring of Natural Killer Cell Reconstitution Against CMV Reactivation After Allogeneic Hematopoietic Stem Cell Transplantation.

    P. Ki Hyun,1 L. Hyeyoung,2 R. Ji Hyeong,1 K. Yonggoo,2 H. Kyungja,2 C. Byung Sik,2 K. Hee-Je,3 M. Woosung,3 O. Eun-Jee.2

    1Department of Biomedical Science, Graduate School, the Catholic University of Korea, Seoul, Korea; 2Department of Laboratory Medicine, the Catholic University of Korea, Seoul, Korea; 3Department of Internal Medicine, the Catholic University of Korea, Seoul, Korea

    Cytomegalovirus (CMV) reactivation has an impact on significant morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). Natural killer (NK) cells are the first…
  • 2017 American Transplant Congress

    Immediate vs Delayed Initiation of CMV Prophylaxis…Safe and Cost Beneficial?

    L. Cotiguala, A. Carlson, C. Truax, B. Sirandas, I. Hall, L. Smith.

    University of Utah Health Care, Salt Lake City, UT

    Background: Recommendations differ on when to initiate valganciclovir (VGCV) for CMV prophylaxis (ppx) after tx. Current labeling states within 10 days of tx. We evaluated…
  • 2017 American Transplant Congress

    Effect of Influenza Vaccination in the Severity of Illness in Hospitalized Transplant Recipients with Laboratory-Confirmed Influenza.

    A. Bagenski,1 F. Silveira.2

    1Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA; 2Medicine, University of Pittsburgh, Pittsburgh, PA

    Objectives: The effectiveness of influenza vaccine in solid organ transplant (SOT) recipients may be decreased due to immunosuppression. Some studies have suggested that influenza vaccination…
  • 2017 American Transplant Congress

    Is Thymic Function Determining Rejection Onset in Heart Transplantation?

    A. Sannier,1,2 R. Dorent,1,3 M. Le Borgne,1 N. Stroumza,1 J. Senemaud,1 L. Louedec,1 F. Andreata,1 A. Gaston,1 C. Deschildre,1 P. Nataf,1,3 A. Couvelard,2 G. Caligiuri,1 A. Nicoletti.1

    1Inserm U1148, Diderot University, Paris, France; 2Pathology Department, Bichat Hospital, Paris, France; 3Cardiac Surgery Department, Bichat Hospital, Paris, France

    The thymus is the primary site of T cell development, involuting into fatty tissue in adults. Thymic function persists in the adulthood and may be…
  • 2017 American Transplant Congress

    Donor Macrophage Depletion from CMV-Latently Infected Hearts Abrogates CMV-Accelerated Chronic Rejection.

    J. Burg,1 T. Andoh,2 N. Haese,2 I. Jones,2 S. Orloff,1 D. Streblow.2

    1Department of Surgery, OHSU, Portland, OR; 2VGTI, OHSU, Hillsboro, OR

    Purpose: Latent donor CMV infection has been shown to accelerate chronic rejection (CR) in a heterotopic rat heart transplant model. CMV latency is associated with…
  • 2017 American Transplant Congress

    Assessment of Cardiosphere-Derived Cell Exosomes as Possible Modulator of Alloimmunity in a Mouse Model of HLA-A2 Allosensitization.

    I. Kim,1 G. Wu,1 N.-N. Chai,1 G. De Couto,2 E. Marban,2 A. Klein,1 S. Jordan.1

    1Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; 2Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA

    Purpose: Mounting data indicate that exosomes, a nanosized membrane particle secreted by cells has immune regulatory properties, including anti-inflammation and mediating autocrine, paracrine, and endocrine…
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