ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Recurrent HCC After Radiofrequency Ablation or Liver Resection Can Be Effectively Treated with Salvage Transplantation.

    H. Muaddi,1 D. Al-Adra,1 J. Shaw,1 D. Grant,1 P. Greig,1 I. McGilvray,1 M. Cattral,1 A. Wei,1 C.-A. Moulton,1 J. Kachura,2 R. Beecroft,2 M. Selzner,1 A. Ghanekar,1 S. Gallinger,1 S. Cleary,1 G. Sapisochin.1

    1General Surgery, University of Toronto, Toronto, ON, Canada; 2Medical Imaging, University of Toronto, Toronto, ON, Canada

    Background:Liver resection (LR) and radiofrequency ablation (RFA) represent curative therapies for early stages of hepatocellular carcinoma (HCC). If tumour recurrence occurs, salvage liver transplant (SLT)…
  • 2017 American Transplant Congress

    Variations in Risk-Appetite Between UK Kidney Transplant Centres and Impact on Patient and Graft Outcomes.

    P. Trotter,1,2 M. Robb,2 D. Summers,1,2 J. Bradley,1 J. Neuberger,2,4 C. Callaghan.2,3

    1Department of Surgery, University of Cambridge, Cambridge, United Kingdom; 2Organ Donation and Transplantation, NHS Blood and Transplant, Bristol, United Kingdom; 3Transplant Unit, Guys and St Thomas' NHS Foundation Trust, London, United Kingdom; 4Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom

    Introduction: Risks associated with deceased donors may be donor-related, organ-related, or both. Variations between transplant centres in the risks they are prepared to accept ('risk…
  • 2017 American Transplant Congress

    Successful Utilization of Deceased Donor Kidney Allografts with KDPI>85: A Single Center Experience.

    A. Agarwal, W. Ally, K. Brayman.

    University of Virginia, Charlottesville, VA

    In December 2014, UNOS implemented broad changes in the new Kidney Allocation System (KAS). Recent UNOS summary reports suggest that nationally, organ discard rates have…
  • 2017 American Transplant Congress

    MicroRNAs Differentiate Between Antibody and T-Cell Mediated Renal Allograft Rejection.

    T. van den Bosch,1 M. Clahsen-van Groningen,2 F. Rezaee,3 D. Nieboer,4 E. Steyerberg,4 C. Baan,1 A. Rowshani.1

    1Internal Medicine, Section of Nephrology and Transplantation, Erasmus University Medical Center, Rotterdam, Netherlands; 2Pathology, Erasmus University Medical Center, Rotterdam, Netherlands; 3Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, Netherlands; 4Public Health, Erasmus University Medical Center, Rotterdam, Netherlands

    Purpose: MicroRNAs are important immune regulators of gene and protein expression. Both circulating and intragraft expression of microRNAs have been related to renal allograft rejection.…
  • 2017 American Transplant Congress

    Medicinal Herb Cordyceps Sinensis Promotes Long-Term Allograft Survival by Tipping the Balance Between CD4+FoxP3+ Tregs and CD8+ Tcm Cells.

    Z. Dai,1 H. Dai.2

    1Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China; 2University of Pittsburgh, Pittsburgh, PA

    Achieving long-term allograft survival or tolerance without continuously global immunosuppression is highly desirable in transplantation. This study was set to induce long-term allograft survival using…
  • 2017 American Transplant Congress

    Hypoxia Induces Tissue Factor Upregulation in Isolated Human Islets.

    B. Sandhu,1 M. Prendecki,1 G. Rutter,1 A. Martinez-Sanchez,1 N. Kanda,1 N. Galloway-Phillips,1 R. Smith,2 C. Pusey,1 V. Papalois.1

    1Imperial College, London, United Kingdom; 2King's College, London, United Kingdom

    Purpose: Early islet loss post-infusion remains a significant problem in islet transplantation, despite the use of heparinised media to abrogate the effects of Tissue Factor…
  • 2017 American Transplant Congress

    Protective Effect of Crepidiastrum denticulatum Extract Pretreatment Against Hepatic Ischemia-Reperfusion Injury in Mice.

    H. Jang, H. Lee, C. Park, D. Eom, J. Lee, M. Oh, J. Yoo, C. Rho.

    Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Anesthesia, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Pathology, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Natural Medicine Center, Korea Institute of Science and Technology, Gangneung, Gangwon, Korea; Natural Medicine Center, Korea Institute of Science and Technology, Gangneung, Gangwon, Korea

    Crepidiastrum denticulatum (CD) is a well-known, traditionally consumed vegetable in Korea, which was recently reported to have bioactive compounds with detoxification and antioxidant properties. Ischemia-reperfusion…
  • 2017 American Transplant Congress

    Bacteremia in Kidney Transplant Recipients: Incidence, Risk Factors, and Outcomes.

    S. Brar, Y. Wang, A. Cannitelli, Y. Li, O. Famure, S. Husain, J. Kim.

    Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada

    Background: Bloodstream infections or bacteremia is a serious complication after kidney transplantation. The incidence, risk factors, and outcomes of bacteremia among kidney transplant recipients have…
  • 2017 American Transplant Congress

    Prediction of Delayed Graft Function in Chinese Kidney Allograft Recipients.

    H. Zhang, S. Qin, L. Zheng, L. Liu, C. Wang.

    Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    Background and Objective: Delay graft function (DGF) is most commonly defined as post-operative dialysis requirement in the first week after renal transplantation. It has a…
  • 2017 American Transplant Congress

    Impact of Everolimus Added to a De Novo Belatacept Regimen on the Risk of BK Viremia After Kidney Transplant.

    C. Larsen,1 M. Alseiari,2 S. Chandran,2 F. Vincenti,2 D. Wojciechowski.1

    1Division of Nephrology, Massachusetts General Hospital, Boston, MA; 2Division of Nephrology, UCSF, San Francisco, CA

    IntroductionBK viremia is a common complication following kidney transplantation. In vitro data suggest that inhibition of the mTOR–SP6-kinase pathway prevents expression of early viral genes…
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