Am J Transplant, Volume 17, Suppl 3 Archives - Page 3 of 181 - ATC Abstracts

2017 American Transplant Congress
Sensitized KPD Pairs Take Longer to Find Matches.
C. Holscher,¹ E. Chow,¹ C. Purcell,² M. Ronin,² J. Garonzik-Wang,¹ A. Massie,¹ S. Gentry,³ D. Segev.¹
¹Johns Hopkins University, Baltimore; ²National Kidney Registry, New York; ³US Naval Academy, Annapolis
Kidney paired donation (KPD) can facilitate living donor transplantation for candidates with an incompatible donor, but it is unclear how sensitization or blood type affects…
2017 American Transplant Congress
African American Living Kidney Donors' Attitudes About APOL1 Genetic Testing: Implications for Evaluation and Informed Consent.
E. Gordon,¹ C. Johnson,¹ C. Wicklund,¹ R. Sharp,² J. Friedewald.¹
¹Northwestern University, Chicago, IL; ²Mayo Clinic, Rochester
BackgroundAfrican American (AA) live kidney donors (LKDs) have a greater risk than European American live donors of kidney failure. Apolipoprotein 1 (APOL1) gene variants in…
2017 American Transplant Congress
Effect of AKI Donor Admit Creatinine on Renal Transplant Outcomes.
E. Giorgakis,¹ R. Heilman,² H. Khamash,² B. Kaplan,² A. Moss,¹ M. Smith,³ K. Reddy.¹
¹Department of Surgery, Mayo Clinic, Phoenix, AZ; ²Department of Medicine, Mayo Clinic, Phoenix, AZ; ³Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ
Purpose of the study was to explore the effect of admit AKI donor creatinine on graft outcomes.Method: Single center retrospective analysis of kidney transplants performed…
2017 American Transplant Congress
Screening and Referral of High Risk Liver Transplant Recipients to a Transitional Care Coordination (TCC) Program to Reduce Hospital Readmissions.
A. Masoumi,¹ J. Krzyzewski,¹ T. Stern,¹ N. Schluterman,² D. Bruno,² J. Bromberg,² R. Barth,² S. Hanish.²
¹University of Maryland Medical Center, Baltimore, MD; ²University of Maryland School of Medicine, Baltimore, MD
Introduction One-fifth of Medicare patients are readmitted to the hospital. The readmission rate among liver transplant recipients at a large tertiary academic medical center in…
2017 American Transplant Congress
Pre-Kidney Transplant Lower Extremity Impairment and Post-Transplant Mortality.
A. Nastasi,^1,2 M. McAdams-DeMarco,^1,2 J. Schrack,¹ H. Ying,² C. Haugen,² M. González Fernández,³ D. Segev.^1,2
¹Epidemiology, Johns Hopkins University, Baltimore, MD; ²Surgery, Johns Hopkins University, Baltimore, MD; ³Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MD
INTRODUCTION. Few objective tests can be easily performed prior to kidney transplantation (KT) to effectively stratify patients by risk of post-KT mortality. The short physical…
2017 American Transplant Congress
Transplanting Hepatitis C Kidneys into Negative KidnEy Recipients [THINKER] Trial.
D. Goldberg, E. Blumberg, R. Reddy, S. Nazarian, V. Van Deerlin, J. Trofe-Clarke, M. Levine, D. Sawinski, R. Bloom, P. Abt, P. Reese.
University of Pennsylvania, Philadelphia
Background: More than 500 kidneys from HCV+ deceased donors are discarded each year, even though direct acting antiviral therapies have cure rates exceeding 95%. We…
2017 American Transplant Congress
Thrombalexin: Use of a Cytotopic Anticoagulant to Reduce Thrombotic Microangiopathy in a Highly Sensitized Model of Kidney Transplantation.
M. Manook,^1,2 J. Kwun,¹ J. Yoon,¹ K. Samy,¹ A. MacDonlad,¹ H. Xu,¹ R. Smith,³ S. Sacks,³ A. Dorling,³ N. Mamode,² S. Knechtle.¹
¹Surgery, Duke Transplant Center, Durham, NC; ²Renal and Transplant, Guy's and St Thomas's NHS Foundation Trust, Sondon, United Kingdom; ³MRC Centre for Transplantation, London, United Kingdom
Introduction:Thrombotic microangiopathy (TMA) is a phenomenon observed in antibody-mediated rejection (AMR) of the kidney transplant, particularly in highly sensitized individuals. Following promising data in a…
2017 American Transplant Congress
To Accept or Not Accept, That Is the Question: Donor Heart Selection Process and Outcome of Discarded Organs Transplanted in Another Center.
A. Aliabadi-Zuckermann,¹ J. Goekler,¹ A. Kaider,² J. Riebandt,¹ R. Moayedifar,¹ E. Osorio,¹ T. Haberl,¹ G. Laufer,¹ J. Smits,³ A. Zuckermann.¹
¹Cardiac Surgery, Medical University of Vienna, Vienna, Austria; ²Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria; ³Eurotransplant Foundation, Leiden, Netherlands
Purpose: The decision making process to accept a donor heart is very complicated, subjective and less associated with evidence based decisions. In this analysis we…
2017 American Transplant Congress
Blood Transfusion Induced Donor Specific Antibodies Are Associated with Rejection and Graft Failure.
S. Hassan,¹ F. Regan,^2,3 C. Brown,⁴ A. Harmer,³ N. Anderson,³ P. Brookes,⁵ D. Taube,¹ M. Willicombe.¹
¹Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; ²Haematology, Imperial College Healthcare NHS Trust, London, United Kingdom; ³NHS Blood and Transplant, London, United Kingdom; ⁴Histocompatibility and Immunogenetics, NHS Blood and Transplant, London, United Kingdom; ⁵Histocompatibility and Immunogenetics, Imperial College Healthcare NHS Trust, London, United Kingdom
Introduction: Although it is well known that blood transfusions post-transplant are associated with the development of both HLA and donor specific antibodies [DSAs] and a…
2017 American Transplant Congress
HLA Eplet Mismatches Predict DSA Formation, Graft Survival, and Re-Transplantation Rate in Pediatric Renal Transplantation.
M. Sypek,^1,2 S. Hiho,³ L. Cantwell,³ P. Hughes,² A. Le Page,⁴ J. Kausman.¹
¹Royal Children's Hospital, Melbourne, Australia; ²Royal Melbourne Hospital, Melbourne, Australia; ³Victorian Transplant and Immunogenetics Service, Melbourne, Australia; ⁴Monash Children's Hospital, Melbourne, Australia
The potential benefits of HLA epitope based matching are greatest for pediatric recipients, however, there is little published data on the association of epitope mismatches…