Am J Transplant, Volume 17, Suppl 3 Archives - Page 3 of 181 - ATC Abstracts

2017 American Transplant Congress
Educational Strategies for Increased Wait-Listing Rates: Opportunities for Dialysis Center Intervention.
A. Waterman,¹ J. Peipert,¹ H. Xiao,² C. Goalby,¹ K. Lentine.²
¹UCLA, Los Angeles, CA; ²SLU, St. Louis, MO
Dialysis centers vary in how well they educate patients about kidney transplant (KT). This study categorized common groups of educational strategies used by dialysis staff;…
2017 American Transplant Congress
Characterization of Human Plasma Cell Proteasome Adaptations to Proteasome Inhibitor Therapy: A Precision Medicine Approach to Overcome Drug Resistance in Desensitization.
J. Driscoll,¹ S. Tremblay,¹ P. Brailey,¹ A. Girnita,¹ R. Alloway,¹ B. Aronow,² H. Singh,² E. Woodle.²
¹U of Cincinnati, Cincinnati, OH; ²Cincinnati Children's, Cincinnati, OH
Purpose: Bone marrow niche-resident plasma cells (BMNRPCs) exhibit variable sensitivity to proteasome inhibitor (PI) therapy. Here, we characterized alterations in the gene and protein expression…
2017 American Transplant Congress
Venous Thromboembolism and the Risk of Death and Graft Loss in Kidney Transplant Recipients.
N. Lam,¹ A. Garg,² G. Knoll,³ J. Kim,⁴ K. Lentine,⁵ E. McArthur,⁶ K. Naylor,⁶ S. Bota,⁶ M. Sood.³
¹University of Alberta, Edmonton, Canada; ²Western University, London, Canada; ³University of Ottawa, Ottawa, Canada; ⁴University of Toronto, Toronto, Canada; ⁵Saint Louis University School of Medicine, St. Louis; ⁶Institute for Clinical Evaluative Sciences, London, Canada
Background: The incidence of venous thromboembolism (VTE) in kidney transplant recipients varies widely in the literature. The implications of VTE for morbidity and mortality in…
2017 American Transplant Congress
Improving Liver Allocation Using Optimized Neighborhoods.
S. Mehrotra, V. Kilambi.
Industrial Engineering and the Management Sciences, Northwestern University, Evanston, IL
Background: Geographic disparities persist in access to liver transplantation. Candidates with similar urgency experience varying opportunities for transplants across the US. Policymakers are poised to…
2017 American Transplant Congress
Poor Outcomes on the Waiting List for Pediatric Lung Retransplant Patients Listed in Low Volume Centers.
B. Scully,¹ J. Heinle,¹ M. Kueht,¹ E. McKenzie,¹ G. Mallory,² E. Melicoff,² A. Rana.¹
¹Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX; ²Department of Pediatrics and Pulmonology, Baylor College of Medicine, Houston, TX
PurposeLow case volume has been associated with lower survival after pediatric lung transplantation. In addition, pediatric lung retransplantation has been associated with low overall survival…
2017 American Transplant Congress
Endoscopic Ultrasound Guided Biopsy Sampling of the Pancreas Transplant- The Future of Graft Surveillance?
E. Nordheim,¹ V. Paulsen,² A. Lars,² R. Horneland,³ K. Brabrand,⁴ A. Hartmann,¹ T. Jenssen.^1,5
¹Section of Nephrology, Department of Transplantation, Oslo University Hospital, Oslo, Norway; ²Section of Gastroenterology, Department of Transplantation, Oslo University Hospital, Oslo, Norway; ³Department of Transplantation, Oslo University Hospital, Oslo, Norway; ⁴Department of Radiology, Oslo University Hospital, Oslo, Norway; ⁵Metabolic and Renal Research Group, The Arctic University of Norway, Tromsø, Norway
Background:Pancreas transplantation (PTX) can improve morbidity and potentially increase survival in selected patients with brittle diabetes. Development of a successful and safe biopsy monitoring program…
2017 American Transplant Congress
Non-Invasive Detection of Rejection with ImmunoPET Imaging.
D. Mathews,¹ K. Lindsay,² P. Santangelo,² Y. Dong,¹ J. Tso,³ A. Adams.¹
¹Department of Surgery, Emory University, Atlanta, GA; ²Department of Biomedical Engineering, Georgia Tech, Atlanta, GA; ³JN Biosciences LLC, Mountain View, CA
Current approaches to detect and diagnose rejection are retrospective and/or invasive. These methods assess the extent of end organ damage by insensitive and non-specific measures…
2017 American Transplant Congress
Induction of Sensitization and Resistance to Transplant Tolerance by Allogeneic Pregnancy.
A. Suah,¹ J. Young,¹ S. Hsu-Wei Khiew,¹ Q. Wang,¹ D. Yin,¹ M.-L. Alegre,² A. Chong.¹
¹Department of Surgery, University of Chicago, Chicago, IL; ²Department of Medicine, University of Chicago, Chicago, IL
Background: Clinical data suggest allogeneic pregnancy is a sensitizing event; yet, recent data from mouse models suggest it induces fetal-specific regulatory T cell (Treg) expansion…
2017 American Transplant Congress
Clinical Correlation of Endomyocardial Biopsies Molecular Profiling: Taking Rejection Diagnosis Beyond Histology.
L. Potena,¹ L. Borgese,¹ A. Gaudenzi,¹ V. Agostini,¹ J. Reeve,² M. Masetti,¹ F. Grigioni,¹ O. Leone,¹ P. Halloran.
¹University of Bologna, Bologna, Italy; ²Alberta Transplant Applied Genomics Centre, Edmonton, Canada
Histology grading of endomyocardial biopsies (EMB), the standard for diagnosing T-cell-mediated (TCMR) and antibody-mediated (ABMR) rejection, has serious issues with reproducibility (Transplantation 94 (11):1172177, 2012)…
2017 American Transplant Congress
Calibration of BK Virus Nucleic Acid Amplification Testing to the 1^st WHO International Standard for BK Virus.
S. Tan,¹ S. Milligan,² M. Sahoo,³ N. Taylor,² B. Pinsky.^1,2,3
¹Department of Medicine, Division of Infectious Diseases, Stanford University School of Medicine, Stanford, CA; ²Clinical Virology Laboratory, Stanford Health Care, Stanford, CA; ³Department of Pathology, Stanford University School of Medicine, Stanford, CA
Significant inter-assay variability in the quantification of BK virus (BKV) DNA has limited the broad applicability of thresholds for the management of BKV infection in…