2017 American Transplant Congress
A New Methodology for Measuring and Monitoring Equity in Access to Deceased Donor Kidney Transplants.
United Network for Organ Sharing, Richmond, VA
Background: The OPTN monitors progress on increasing the number of transplants, improving patient outcomes, and other goals. However, a well-established methodology for assessing system performance…2017 American Transplant Congress
The Natural History of Kidney Rejection: How Do Molecular Disease States Change Over Time in Patients with Repeat Indication Biopsies?
University of Alberta, Edmonton, AB, Canada
Molecular phenotypes are highly reproducible, but how do they evolve over time? In an unsupervised microarray analysis, 1208 kidney transplant biopsies were assigned to one…2017 American Transplant Congress
The Degree of NK Cell Activation Determines the Ability of Donor-Specific Antibodies to Mediate Acute vs. Chronic Rejection of Kidney Allografts.
While the incidence of antibody-mediated kidney graft rejection has increased, the key cellular and molecular participants underlying this graft injury remain unclear. We have previously…2017 American Transplant Congress
Intensive Care Unit Enhanced Recovery Pathway for Liver Transplant Recipients: A Prospective, Observational Study.
Vanderbilt University Medical Center, Nashville
Purpose: Surgical clinical pathways have been shown to be effective for enhanced recovery and cost reductions, yet have not be tested in liver transplant (LT)…2017 American Transplant Congress
Quantitative Analysis of 10-Year Surveillance Renal Allograft Biopsies.
Introduction. Assessing late histologic changes in renal allografts is important to investigating etiology and devising treatment. Compared to the usual semi-quantitative reading by a renal…2017 American Transplant Congress
KDPI and Small (<20 kg) Pediatric Kidney Donors.
1Seattle Children's Hospital, Seattle; 2Scientific Registry of Transplant Recipients, Minneapolis
Use of small (≤20 kg) donor kidneys in pediatric candidates has declined under the new kidney allocation system (KAS), from 5.0% of pediatric kidney-alone transplants…2017 American Transplant Congress
CCR7+CD8+ T Cell Suppresses Effector T Cell Related Allo-Immune Responses in Kidney Transplant Recipients.
Internal Medicine, Seoul St. Mary's Hospital, Seoul, Korea
Background; Previously reports showed that CCR7+CD8+ T cells have suppressive effect on various pathogenic immune cells. The aim of this study is to investigate the…2017 American Transplant Congress
Dual Costimulatory Blockades Failed to Achieve Transplant Tolerance Despite Induction of Mixed Chimerism in NHPs.
Background: Our previous studies showed that substantial deletion of CD8+ memory T cells (TMEM) was necessary to induce mixed chimerism (MC) and allograft tolerance when…2017 American Transplant Congress
10 Years or More of Follow Up After Total Pancreatectomy and Intra Portal Islet Auto Transplantation (TP/IAT) for Treatment of Chronic Pancreatitis, Is It a Durable Operation?
Surgery, University of Minnesota, Minneapolis
Background: Total pancreatectomy and intra-portal islet cell auto-transplantation (TP/IAT) is increasingly being utilized for the management of chronic pancreatitis (CP), the benefits being removal of…2017 American Transplant Congress
Hepatic Ischemia Reperfusion Injury After Liver Transplantation Is Associated with Acute Kidney Injury.
Background: The impact of liver allograft ischemia/reperfusion injury (IRI) on native renal function remains to be characterized. We hypothesized that severity of IRI correlates with…
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