ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    TRPV4 Channels Mediate Pulmonary Edema and Inflammation During Ischemia-Reperfusion Injury.

    E. Charles, Y. Zhao, K. Hong, C. Marziano, J. Mehaffey, I. Kron, S. Sonkusare, V. Laubach, A. Sharma.

    University of Virginia, Charlottesville, VA

    Rationale: Lung ischemia-reperfusion (IR) injury remains a major challenge in post-transplant patients. Transient receptor potential vanilloid 4 (TRPV4) cation channels mediate cellular calcium influx, and…
  • 2017 American Transplant Congress

    Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes (T1D) Post Renal Transplantation.

    J. Markmann, R. Alejandro, M. Bellin, N. Bridges, W. Clarke, T. Eggerman, E. Foster, B. Hering, D. Kaufman, O. Korsgren, X. Luo, A. Naji, J. Oberholzer, A. Posselt, M. Rickels, C. Ricordi, M. Robien, P. Senior, A. Shapiro, N. Turgeon.

    CIT Consortium

    Introduction: From a risk-benefit perspective, patients with type 1 diabetes (T1D) who are already obligated to long-term immunosuppression to support a kidney transplant and who…
  • 2017 American Transplant Congress

    Chronic Antibody Mediated Rejection (cABMR) in ABO-Incompatible and ABO-Compatible Kidney Transplants: A Single US Center Experience.

    S. Sethi, A. Vo, E. Huang, L. Varanasi, J. Choi, A. Peng, R. Najjar, S. Jordan.

    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA

    Introduction:Similar patient and graft outcomes have been previously reported for ABO compatible (ABOc) and ABO incompatible (ABOi) kidney transplants. However, data are limited on the…
  • 2017 American Transplant Congress

    Poor Prediction of Rejection and Kidney Survival by Donor-Specific-Antibodies Characterization.

    L. Couzi,1,2,3 M. Courant,1 J. Visentin,1,2,3 V. Dubois,4 S. Lepreux,1,2 G. Guidicelli,1 O. Thaunat,5,6 P. Merville,1,2,3 J.-L. Taupin.7

    1CHU de Bordeaux, Bordeaux, France; 2Université de Bordeaux, Bordeaux, France; 3UMR CNRS 5164 Immunoconcept, Bordeaux, France; 4Etablissement Français du Sang, Lyon, France; 5INSERM U1111, Lyon, France; 6CHU de Lyon, Lyon, France; 7Laboratoire d'Immunologie et Histocompatibilité, Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Louis, Paris, France

    Kidney transplant recipients with DSA have a greater likelihood of developing antibody-mediated rejection (ABMR) and kidney allograft loss. The aim of this study was to…
  • 2017 American Transplant Congress

    Liver Mesenchymal Stem Cells Inhibit T Cell Alloresponses.

    T. Taner, M. Gustafson, M. Hansen, A. Dietz, M. Stegall.

    Mayo Clinic, Rochester, MN

    Clinical and histologic evidence suggest that the liver allograft induces alloimmune hyporesponsiveness in the recipient. Mesenchymal stem cells (MSC) are multipotent non-hematopoietic stromal cells with…
  • 2017 American Transplant Congress

    Prognostic Tools to Choose Candidates for Successful Desensitization.

    D. Pinelli,1 A. Zachary,2 J. Friedewald,1 M. Leffell,2 D. Lucas,2 R. Montgomery,2 A. Tambur.1

    1Northwestern University, Chicago, IL; 2Johns Hopkins, Baltimore, MD

    Antibodies to donor HLA antigens are a barrier to solid organ transplantation. Strategies to desensitize patients have improved, but the ability to predict response to…
  • 2017 American Transplant Congress

    Hepatic Artery and Biliary Complications in Liver Transplant Recipients with Radioembolization Bridging Treatment for Hepatocellular Carcinoma.

    S. Radunz,1 J. Treckmann,1 F. Saner,1 S. Müller,2 J. Theysohn,3 A. Paul,1 T. Benkö.1

    1General, Visceral and Transplant Surgery, University Hospital Essen, Essen, Germany; 2Nuclear Medicine, University Hospital Essen, Essen, Germany; 3Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany

    Locoregional treatments are commonly applied in hepatocellular carcinoma (HCC) patients as a bridge to liver transplantation to prevent tumor progression during waiting time. We hypothesized…
  • 2017 American Transplant Congress

    Outcomes Following Transplantation for Hepatocellular Carcinoma.

    P. Tabrizian, K. Nakazawa, J. Prigoff, M. Schwartz, S. Florman.

    Transplant, Recanati/Miller Transplantation Institute, New York, Ny

    Objectives: To examine the prognostic features and outcomes of patients undergoing transplantation for hepatocellular carcinoma (HCC).Methods: A single-institution retrospective chart review was performed on all…
  • 2017 American Transplant Congress

    The Impact of the Kidney Allocation System on Outcomes for Kidneys with KDPI > 85%.

    A. Perry,1 J. Sageshima,1 C. Santhanakrishnan,1 J. McVicar,1 C. Troppmann,1 A. De Mattos,2 J. Woloszyn,1 R. Perez.1

    1Division of Transplant Surgery, University of California, Davis, Sacramento, CA; 2Division of Transplant Medicine, University of California, Davis, Sacramento, CA

    Single center outcomes were examined to assess the impact of the implementation of the Kidney Allocation System (KAS) on outcomes for kidneys with KDPI >85%.Methods:…
  • 2017 American Transplant Congress

    Zero-Time Biopsy of Potential Donor Kidneys to Aid Decision-Making: A 9-Year Single-Center Experience.

    Y. Luque, O. Aubert, F. Martinez, L. Amrouche, C. Tinel, L. Galmiche, L.-H. Noel, J.-P. Duong, F. Audenet, C. Legendre, D. Anglicheau, M. Rabant.

    Necker-Enfants Malades, Tenon and European Georges Pompidou Hospitals, Paris, France

    The added benefits of zero-time biopsy of a potential donor kidney on top of standard donor biological and clinical data to aid in the decision…
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