ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    CD47 Blockade Reduces Ischemia/Reperfusion Injury in Donation After Cardiac Death Rat Kidney Transplantation.

    X. Wang,1 M. Xu,1 J. Jia,1 Z. Zhang,1 J. Gaut,2 G. Upadhya,1 P. Manning,3 Y. Lin,1 W. Chapman.1

    1Department of Surgery, Washington University School of Medicine, Saint Louis; 2Pathology and Immunology, Washington University School of Medicine, Saint Louis; 3Tioma Therapeutics, Saint Louis

    Purpose: We evaluated the potential effects of antibody-mediated CD47 blockade to modulate vascular endothelial nitric oxide activity and reduce ischemia reperfusion injury in a rat…
  • 2017 American Transplant Congress

    Importance of Acquisition of Carbapenemase (KPC)-Producing Enterobacteriaceae in Solid Organ Transplant Recipients: A Single-Center Experience.

    S. Han,1 K. Lee,1 K.-A. Lee,1 H. Paik,2 J. Lee,2 M. Kim,3 D. Joo,3 J. Choi,3 S. Kim,3 Y. Kim.3

    1Divison of Infectious Disease, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea; 2Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea; 3Department of Transplantation Surgery, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea

    Background: Among multi-drug resistant bacteria, carbapenem-resistant Enterobacteriaceae (CRE) is recently spreading in several countries. Carbapenemase-producing (CP) Enterobacteriaceae (CPE) has great clinical importance because it could…
  • 2017 American Transplant Congress

    The Relationship Between Frailty and Decreased Physical Performance with Death on the Kidney Transplant Waiting List.

    E. Lorenz, F. Cosio, S. Bernard, S. Bogard, B. Bjerke, E. Geissler, S. Hanna, W. Kremers, M. Stegall, A. Cheville, N. LeBrasseur.

    Mayo Clinic, Rochester

    Background: Frailty and decreased physical performance are associated with poor outcomes after kidney transplant. Less is known about their relationship with pre-transplant outcomes. The aim…
  • 2017 American Transplant Congress

    State Population Health and Center-Level Variation in Rate of Living Kidney Donation.

    R. Reed, B. Shelton, P. MacLennan, M. Hanaway, V. Kumar, R. Gaston, J. Locke.

    University of Alabama at Birmingham, Birmingham

    Background: Comorbid conditions that exclude individuals from living kidney donation are highly prevalent in the United States, but the relationship between population characteristics and the…
  • 2017 American Transplant Congress

    A Multidimensional Prognostic Score and Nomogram to Predict Kidney Transplant Survival: The Integrative Box (iBox) System.

    A. Loupy,1 O. Aubert,1 B. Orandi,2 A. Jackson,2 M. Naesens,3 N. Kamar,1 O. Thaunat,1 E. Morelon,1 M. Delahousse,1 D. Viglietti,1 D. Glotz,1 C. Legendre,1 X. Jouven,1 R. Montgomery,2 M. Stegall,4 D. Segev,2 C. Lefaucheur.1

    1Paris Translational Research Center for Organ Transplantation, Paris, France; 2Johns-Hopkins, Baltimore; 3Leuven University, Leuven, Belgium; 4Mayo Clinic, Rochester

    The transplant field currently lacks of robust risk stratification models leading to major problems for clinical care, clinical trials, and medical progress. The goal of…
  • 2017 American Transplant Congress

    Outcomes of Hand Assisted Laparoscopic Right Donor Nephrectomy, Single Center Experience.

    A. El-Hinnawi, A. Rajab, R. Pelletier.

    Transplant Surgery, The Ohio State Wexner Medical Center, Columbus, OH

    Right donor nephrectomy,especially when conducted laparoscopically,has not been accepted by most transplant surgeons because of the consequent short right renal vein and the possible increased…
  • 2017 American Transplant Congress

    Induction Therapy in Low Risk Elderly Kidney Transplant Recipients: Donor Factors.

    F. Al Ammary, M. DeMarco, Q. Huang, E. King, S. Bay, A. Muzaale, A. Wiseman, D. Segev.

    Johns Hopkins, Baltimore; University of Colorado, Denver

    It is not known whether depleting induction is needed in low-risk elderly kidney transplant (KT) recipients in whom concern for infectious and complications is higher…
  • 2017 American Transplant Congress

    A Mutation of the Erythropoietin Receptor Correlates with Improved Function of Deceased-Donor Renal Transplants.

    M. Fischereder,1 S. Friedrich,1 U. Klingmüller,2 T. Kauke,3 T. Breidenbach,4 D. Boesebeck,5 E. Angelika,5 C. Cohen,1 B. Banas,6 M. Guba,7 M. Stangl,8 B. Krämer,9 C. Hugo,10 K. Lopau,11 M. Stadtler,12 T. Mone.12

    1Medizinische Klinik IV, Klinikum der LMU, Munich, Germany; 2DKFZ, Heidelberg, Germany; 3Klinikum der LMU, Munich, Germany; 4Chirurgische Klinik, Klinikum Augsburg, Augsburg, Germany; 5DSO Bayern, Munich, Germany; 6Nephrologie, Universitätsklinikum, Regensburg, Germany; 7Surgery, Klinikum der LMU, Munich, Germany; 8Surgery, Klinikum der TU, Munich, Germany; 9Innere Medizin IV, Universitätsklinikum, Mannheim, Germany; 10Innere Medizin, Universität Erlangen, Erlangen, Germany; 11Innere Medizin 2, Universitätsklinikum, Würzburg, Germany; 12OneLegacy, Los Angeles

    Erythropoietin (Epo) protects renal tubular cells from ischemia/reperfusion injury in experimental transplantation, suggesting a relevant effect of erythropoietin receptor (EPOR) mediated signalling. Previously 6 mutations…
  • 2017 American Transplant Congress

    Donor Derived Transmission Events in 2015-2016: Analysis of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).

    C. Wolfe,1 M. Clark,2 S. Tlusty,2 D. Kaul,1 M. Michaels.1

    1DTAC, Richmond; 2United Network for Organ Sharing, Richmond

    The OPTN DTAC, a multidisciplinary committee, evaluates potential donor derived transmission events (PDDTE), including mostly infections (I) & malignancies (M), to assess for likelihood of…
  • 2017 American Transplant Congress

    Outcomes Following Cholecystectomy in Kidney Transplant Recipients.

    S. DiBrito, C. Holscher, I. Olorundare, C. Haugen, Y. Alimi, D. Segev, J. Garonzik-Wang.

    JHU, Baltimore

    Cholecystectomy is one of the most common general surgical procedures. Given the need for lifelong immunosuppression and the physiologic impact of years of renal replacement,…
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