Am J Transplant, Volume 17, Suppl 3 Archives - Page 3 of 181 - ATC Abstracts

2017 American Transplant Congress
Outcomes of Moderately to Severely Steatotic Grafts in Liver Transplantation: A Meta-Analysis.
K. Bonner,¹ C. Thongprayoon,² W. Cheungpasitporn,¹ M. Leise.¹
¹Mayo Clinic, Rochester; ²Bassett Medical Center, Cooperstown
Background/Objectives:There is a worldwide need to expand the pool of available liver grafts. Livers with >50% steatosis are discarded for orthotopic liver transplantation (OLT) by…
2017 American Transplant Congress
Impact of Early Pancreas Graft Failure on Patient and Kidney Graft Survival After Simultaneous Pancreas and Kidney Transplantation (SPK).
A. Gruessner, M. Laftavi, V. Whittaker, Z. Acun, O. Pankowycz, R. Gruessner.
SUNY Upstate Medical University, Syracuse, NY
Introduction: In SPK transplants, the major risk factors for poor patient survival are early pancreas and/or kidney graft loss. In this study, we specifically examined…
2017 American Transplant Congress
Simultaneous Pancreas/Kidney Transplant Recipients Are Predisposed to Symptomatic CMV-Infection and Concomitant Infectious Complications.
T. Schachtner,^1,2,3 M. Zaks,¹ A. Kahl,¹ P. Reinke.^1,2
¹Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; ²Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany; ³Berlin Institute of Health BIH, Berlin, Germany
Infections have increased in simultaneous pancreas/kidney transplant recipients (SPKTRs) with CMV-infection being the most important viral infection with adverse impact on patient and allograft outcomes.…
2017 American Transplant Congress
Transplant Professionals' Attitudes and Approaches to the Living Kidney Donor-Recipient Relationship: Interview Study.
A. Ralph,^1,2,3 P. Butow,^3,4,5 J. Craig,^1,2 J. Chapman,⁸ J. Gill,⁶ J. Kanellis,⁷ A. Tong.^1,2
¹Sydney School of Public Health, University of Sydney, Sydney, Australia; ²Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia; ³School of Psychology, University of Sydney, Sydney, Australia; ⁴Psycho-Oncology Co-Operative Research Group, University of Sydney, Sydney, Australia; ⁵Centre for Medical Psychology & Evidence-Based Decision-Making, University of Sydney, Sydney, Australia; ⁶Division of Nephrology, University of British Columbia, Vancouver, Canada; ⁷Department of Nephrology, Monash Health and Centre for Inflammatory Diseases, Department of Medicine, Monash University, Melbourne, Australia; ⁸Centre for Transplant and Renal Research, University of Sydney, Sydney, Australia
Background: Assessment of the donor-recipient relationship is recommended by international guidelines to prevent undue coercion and ensure realistic expectations. We aimed to describe attitudes and…
2017 American Transplant Congress
Incidence, Recurrence and Long Term Survival Post Chemotherapy in Renal Transplant Recipients with Post Transplant Lymphoproliferative Disorder: Single Center Study.
R. Rathore, K. Tomlinson, H. Dukka, D. Farrugia, M. Lambie.
Department of Renal Medicine, University Hospitals of North Midlands, Stoke-on-Trent, United Kingdom
Background: Majority of Post transplant lymphoproliferative disorders(PTLD) occur in the first year post solid organ transplant. The risk factors for development of PTLD include degree…
2017 American Transplant Congress
CD4⁺IFN-γ⁺IL-10⁺ Regulatory Type 1 Cells Facilitate Prolongation of Graft Survival in Old Recipient Mice Treated with Rapamycin.
T. Heinbokel, M. Quante, K. Minami, A. Elkhal, S. Tullius.
Transplant Surgery Research Laboratory and Division of Transplant Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Although the elderly represent a rapidly growing population among transplant recipients, age-specific aspects have not been considered sufficiently in clinical trials. Moreover, age-specific effects of…
2017 American Transplant Congress
Does Blockade of ICOS/ICOS-L Pathway Act Synergistically with αCD40 Costimulation Pathway Blockade?
N. O'Neill, T. Zhang, X. Cheng, W. Sun, G. Braileanu, I. Tatarov, W. Hassanein, A. Azimzadeh, R. Pierson.
University of Maryland School of Medicine, Baltimore, MD
Purpose: Inducible costimulator (ICOS) on T cells enhances basic T cell responses to foreign antigen, and increased ICOS expression is detected in association with pathogenic…
2017 American Transplant Congress
Decellularized Rat Liver Scaffolds Support Survival and Metabolic Function of Multilineage Allogenic Cells.
W. Hassanein, A. Werdesheim, A. Cimeno, B. Buckingham, A. Khalifeh, M. Uluer, J. Harrison, D. Parsell, C. Drachenberg, R. Barth, J. LaMattina.
University of Maryland School of Medcine, Baltimore, MD
Background:Organ bioengineering has the potential to completely eliminate the donor organ shortage. Here, we examine the feasibility of a decellularized liver construct to support the…
2017 American Transplant Congress
Pre-Transplant Recipient Transcriptomic Profile May Predict Delayed Graft Function (DGF) in Kidney Transplantation.
P. Pontrelli,¹ F. Rascio,² F. Pesce,¹ M. Accetturo,¹ G. Castellano,¹ G. Zaza,³ A. Lupo,³ M. Fiorentino,¹ L. Gesualdo,¹ G. Stallone,² G. Grandaliano.²
¹University of Bari, Bari, Italy; ²University of Foggia, Foggia, Italy; ³University of Verona, Verona, Italy
Background: DGF is associated with a reduced long-term graft survival. Ischemia-reperfusion damage and donors' features have been always considered as key pathogenic factors in this…
2017 American Transplant Congress
Performance Comparison of Barcoded Oligos and Standard qPCR on Matched FFPE and RNAlater-Submerged Human Kidney Allograft Samples.
T. Sigdel, M. Nguyen, D. Dobi, J. Liberto, S.-C. Hsieh, F. Vincenti, M. Sarwal, Z. Laszik.
University of California, San Francisco, San Francisco
Background: Gene expression profiling can improve the diagnostic ability of kidney allograft injury. Fresh tissue is the favored study material for transcriptomic analysis due to…