2017 American Transplant Congress
Impact of Donor Genotype on Recipient Tacrolimus Pharmacokinetics: The Liver Matters.
1U of Cinicnnati, Cincinnati; 2Cincinnati Children's, Cincinnati; 3iC42 Clinical Research, Colorado
Tacrolimus (Tac) is a cornerstone immunosuppressant metabolized in the gut and liver, resulting in high intra/inter patient pharmacokinetic (PK) variability. Recipient genotype (RG) impacts tac…2017 American Transplant Congress
Treating Refractory Liver Allograft Rejection with Photopheresis.
DSAs with persistent high titer alloantibodies are associated with refractory antibody mediated rejection (AMR) and liver injury.METHODS: We present 4 liver transplant (LT) patients refractory…2017 American Transplant Congress
Comparison of the Estimated and Measured Glomerular Filtration Rate in Kidney Donor Candidates.
Nephrology, Houston Methodist Hospital, Houston, TX
Background and objectivesThe assessment of GFR in kidney donor candidates is necessary for the appropriate allocation of donor kidneys to recipients. This assessment can be…2017 American Transplant Congress
Recurrence of IgA Nephropathy After Kidney Transplantation in Maintenance Steroids versus Steroid Avoidance Regimens: A UNOS/OPTN Analysis.
Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA
Background: There has been an increase in the use of steroid-avoidance regimens. However, there is some evidence to suggest that steroid avoidance may be associated…2017 American Transplant Congress
Metabolomics Study for Identification of Potential Biomarkers of Long-Term Survival in Kidney Transplantation Recipients.
Background: The development of new strategies to improve long-term survival outcome after kidney transplantation is also becoming important. Although current diagnosis of allograft dysfunction relies…2017 American Transplant Congress
Transplant Center Knowledge and Planned Practice of HIV Positive-to-Positive Transplants.
Background: The HIV Organ Policy Equity (HOPE) Act (2013) allows deceased and living donor transplantation of HIV-infected (HIV+) organs into HIV+ recipients (HIV-to-HIV) under HRSA…2017 American Transplant Congress
Global Kidney Exchange.
Introduction: Innovative solutions are required to overcome the organ shortage.Methods: The cost differential between dialysis and transplantation in some countries allows the exchange of kidneys…2017 American Transplant Congress
Lower Mean Tacrolimus Troughs Increase Risk of De Novo Donor-Specific Antibodies in the First Year of Kidney Transplant.
University of Colorado, Aurora, CO
Development of de novo donor-specific antibodies (dnDSA) is the first step in the evolution of antibody-mediated rejection, which constitutes the leading cause of death-censored graft…2017 American Transplant Congress
Multicenter Validation of a Clinicopathologic Risk Score to Predict Hepatocellular Carcinoma Recurrence Following Liver Transplantation: Analysis of 4984 Patients from the US Multicenter HCC Transplant Consortium.
Objective: Recurrence of hepatocellular carcinoma (HCC) following liver transplantation (LT) negatively impacts survival. Existing risk prediction models either lack external validation or limit their scope…2017 American Transplant Congress
Redefining Pediatric Heart Status 1A and 1B Criteria: Results of Early Policy Evaluation.
Background. On March 22, 2016, changes to the definitions of pediatric Status 1A and 1 B criteria were implemented in the US. These changes were…
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