2017 American Transplant Congress
The Impact of Tacrolimus and MPA Derivative Immunosuppression on Acheived GFR in Recipients without Rejection: A Comparison of GFR of Living Donor Recipient Pairs at Six Months Post-Transplant.
Medicine, Division of Nephrology, Sacred Heart Hospital, Pensacola, FL
Analysis of the difference in estimated GFR (eGFR) of living donor recipient pairs at six months post-transplant showed that increased use of tacrolimus and MPA…2017 American Transplant Congress
Biomarkers of Epithelial-Mesenchymal Transition (EMT) in Chronic Allograft Nephropathy: Potential for Early Detection and Development of Novel Therapeutic Agents.
Pathology, BioChemistry and Medical Laboratory Sciences, Rush University Medical Center, Chicago, IL
Purpose: To detect markers and novel treatment targets related to fibrogenesis and eventual graft loss by focusing on Epithelial Mesenchymal transition (EMT) which requires understanding…2017 American Transplant Congress
Even Non-Donor-Specific HLA-Antibodies Are Associated with a Progressive Decline in Kidney Transplant Function.
University Spital Zuerich, Zuerich, Switzerland
Donor-specific anti-HLA-Antibodies (DSA) have been shown to be associated with antibody-mediated rejection episodes and a poorer long-term kidney graft function. The impact of anti-HLA-antibodies without…2017 American Transplant Congress
Kidney Waitlist Management: The Readiness Model of Predicting Transplants Under the Kidney Allocation System.
Transplant Center, Massachusetts General Hospital, Boston, MA
Based on the Organ Procurement and Transplantation Network data, between 2001 and 2016 the national kidney wait-list has grown from 51,271 to 100,791 (97%). At…2017 American Transplant Congress
It's Never too Early to Test: Frequent Anti-A2 Titer Monitoring in Blood Group B Patients is Necessary.
Medstar Georgetown Transplant Institute, Washington, DC
Introduction:With the implementation of the new Kidney Allocation System (KAS), deceased donor transplants from blood group A2 donors can now be implanted into blood group…2017 American Transplant Congress
Biological Interplay Between Circulating HLA-sp Alloreactive Memory B-Cells and Long-Lived Plasma Cells in Kidney Transplant Patients Undergoing Chronic ABMR.
Alloreactive humoral responses are one of the main causes of immune-mediated allograft injury in kidney transplantation. Different biological compartments are involved in the generation and…2017 American Transplant Congress
Sirolimus Prolonged Survival After Living Donor Liver Transplantation for HCC Beynd Milan Criteria; Outcome of a Multicenter Prospective Randomized Phase II Trial (ClinicalTrials.gov Identifier: NCT01374750).
Background:It is unclear whether the reported benefit of mTORi in LT for HCC is from direct effect of mTOR inhibitors. We aimed to compare directly…2017 American Transplant Congress
Autophagy Regulates LG3 Maturation and Export in Apoptotic Exosome-Like Vesicles.
Background: Autoantibodies to apoptotic antigens such as LG3 – a C-terminal fragment of perlecan– are present pre-transplantation and contribute to organ rejection in renal transplant…2017 American Transplant Congress
Post-Donation Remaining Donor Kidney Function as Measured by CKD-EPI Formula at 2 Years Correlates and Is Predicted by Remaining Donor Kidney Volume.
Indiana University School of Medicine, Indianapolis
Aim: The aim of our study was to evaluate whether preserved kidney volume correlates with and can predict donor renal function at 2-years post-donation using…2017 American Transplant Congress
De Novo Use of Everolimus Reduces Late-Onset Cytomegalovirus Primary Disease Occurring After Antiviral Prophylaxis Discontinuation in Kidney Transplant Recipients.
Background: Donor (D)+/recipient (R)- serostatus is critically associated with an higher risk of cytomegalovirus (CMV) infection and disease. Antiviral prophylaxis is conventionally used in such…
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