ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Long-Term Clinical Outcomes of Kidney Transplant Recipients with Body-Size Mismatch Between Recipient and Donor.

    Y. Takada,1 D. Iwami,1 K. Hotta,1 K. Kanagawa,2 H. Higuchi,1 T. Hirose,1 H. Sasaki,1 N. Shinohara.1

    1Urology, Hokkaido University Hospital, Sapporo, Hokkaido, Japan; 2Urology, Asahikawa City Hospital, Asahikawa, Hokkaido, Japan

    [Purpose]In living-donor kidney transplantation between large recipient and small donor, there are concerns of lower graft function and poor graft survival. Thus, we aimed to…
  • 2017 American Transplant Congress

    Tangible Benefits in Caregiving Burden Among Spouses/Partners of Transplant Patients: Adding “Donor Benefit” to Live Donor Risk Assessment.

    S. Rasmussen, L. Duquette, M. Henderson, D. Segev.

    JHU, Baltimore

    Background The mental and physical health of spouses and co-habiting partners (dyads) are highly correlated. Dialysis entails significant caregiving burden and decreases the quality of…
  • 2017 American Transplant Congress

    Changes in Urinary Neutrophil Gelatinase Associated Lipocalin Combined with Urine Cytokines and Microalbuminuria as Predictors for Interstitial Fibrosis and Tubular Atrophy in Kidney Transplantation: A Matched-Pair Tissue Cohort Study.

    W. Chancharoenthana,1 A. Leelahavanichkul,1 S. Wattanatorn,1 J. Issara-Amphorn,2 Y. Avihingsanon,1 K. Praditpornsilpa,1 N. Townamchai.1

    1Division of Nephrology, Department of Medicine, Chulalongkorn University, Bangkok, Thailand; 2Research Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

    Background: Late graft loss from interstitial fibrosis - tubular atrophy (IF/TA) continues to be the “Achilles' heel” of kidney transplantation (KT). Long-term calcineurin inhibitors (CNIs)…
  • 2017 American Transplant Congress

    Deceased Donor-Initiated Non-Simultaneous Extended Altruistic Donor Chains Through the Military Share Program.

    M. Rees,1,2 O. Ekwenna,1 E. Elster,3 A. Patel,3 D. Murtagh, Jr,1 A. Roth,4 K. Krawiec,5 J. Arrington,6 I. Ashlagi,4 J. Hawksworth.3

    1U Toledo, Toledo, OH; 2Alliance for Paired Donation, Perrysburg, OH; 3Walter Reed National Medical Center, Bethesda, MD; 4Stanford U, Palo Alto, CA; 5Duke U, Durham, NC; 6Buckeye Transplant, Findlay, OH

    Introduction: At a recent White House Summit on organ transplantation, the Department of Defense (DoD) announced that they would direct some Military Share deceased donor…
  • 2017 American Transplant Congress

    A Brief Frailty Assessment and Outcomes Among Candidates for Liver Transplantation.

    M. Serper, K. Dwinnells, T. Bittermann, K. Olthoff.

    Medicine, University of Pennsylvania, Philadelphia, PA; Surgery, Division of Transplant Surgery, University of Pennsylvania, Philadelphia, PA

    Introduction: As frailty correlates with post-transplant outcomes, brief frailty measures are needed in clinical practice to appropriately risk stratify LT candidates. We used an abbreviated…
  • 2017 American Transplant Congress

    Effective Targeting Plasma Cells with Daratumumab (Anti-CD38) and Mozobil (Anti-CXCR4) in a Sensitized Non-Human Primate Model.

    J. Kwun,1 B. Ezekian,1 M. Manook,1 E. Branum,1 V. Curfman,1 J. Park,1,2 K. Freishlag,1 J. Yoon,1 S. Knechtle.1

    1Surgery, Duke Transplant Center, Durham, NC; 2Surgery, Samsung Medical Center, Seoul, Korea

    [Introduction] The presence of donor-specific antibodies (DSA) leads to antibody-mediated rejection (AMR) and decreased graft survival. Therefore efforts continue to be made to reduce DSA…
  • 2017 American Transplant Congress

    Can Viral Load Be Used as a Surrogate Marker in Clinical Studies of Cytomegalovirus in Solid Organ Transplantation: A Systematic Review and Metaanalysis.

    Y. Natori,1 A. Alghamdi,1 D. Kumar,1 V. Miller,2 P. Ljungman,3 S. Husain,1 A. Humar.1

    1Multi-Organ Transplant Program, UHN, Toronto, Canada; 2UC-Berkeley, Berkeley; 3Karolinska Inst., Solna, Sweden

    Background: Regulatory trials assessing CMV drugs have utilized symptomatic CMV disease as the primary endpoint. However CMV disease occurs infrequently, CMV syndrome is nonspecific, and…
  • 2017 American Transplant Congress

    De Novo Donor-Specific Antibodies After Allograft Nephrectomy.

    G. Lucisano,1 P. Brookes,2 E. Santos-Nunez,2 N. Firmin,2 N. Gunby,2 S. Hassan,1 A. Gueret-Wardle,1 M. Willicombe,1 D. Taube.1

    1Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; 2Histocompatibility and Immunogenetics, Imperial College Healthcare NHS Trust, London, United Kingdom

    Introduction: although the development of donor-specific antibodies (DSAs) is a known event after allograft nephrectomy (Nx), there are few studies describing the tempo, class and…
  • 2017 American Transplant Congress

    Longitudinal Study of Donor Specific Antibodies in a Pediatric Kidney Transplant Population; Response to Optimization of Anti-Proliferative Therapy.

    A. Rounds, M. Moss, M. Bock, J. Goebel.

    Children's Hospital Colorado, Aurora, CO

    In 2015 we implemented surveillance donor-specific antibody (DSA) monitoring in our pediatric kidney transplant recipients (pKTR); we found that in stable pKTRs (i.e. no changes…
  • 2017 American Transplant Congress

    20 and 25-Year Outcomes Following Pediatric Liver Transplantation.

    W. Andrews,1 N. Gupta,2 U. Ekong.3

    1Ped. Surgery, Children's Mercy Hospital, Kansas City, MO; 2Div. Peds. Gastro., Emory, Atlanta, GA; 3Div. Peds. Gastro., Yale, New Haven, CT

    Background: Improved 1,5, & 10- year survival following Pediatric Liver Transplantation (LT) has been demonstrated. However 20 and 25-year patient and graft outcomes (including cause…
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