ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Intravoxel Incoherent Motion MRI Is an Effective Way to Monitor Acute Allograft Rejection in Rat Models.

    S. Zeng, X. Hu.

    Urology, Chao-Yang Hospital, Beijing, China

    Objectives: To combine the intravoxel incoherent motion MRI and blood oxygen level-dependent MRI for assessment of the renal allograft pathological process undergoing acute rejection and…
  • 2017 American Transplant Congress

    New Approach for Targeted Immunotherapy in Vascularized Composite Allotransplantation.

    F. Feturi,1 H. Wang,2 Y. Brudno,2 V. Erbas,3 Z. Zhang,3 H. Sahin,3 D. Mooney,2 V. Gorantla,3 R. Venkataramanan.1

    1Department of Pharmaceutical Science, University of Pittsburgh School of Pharmacy, Pittsburgh, PA; 2A Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA; 3Department of Plastic and Reconstructive Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA

    Vascularized composite allotransplantation (VCA) have highly immunogenic skin component mandates high doses of systemic immunosuppressive drugs. Oral dosing leads to fluctuating, unpredictable blood levels that…
  • 2017 American Transplant Congress

    Steatotic Human Livers Show Inferior Function Compared to Non-Steatotic Livers During Ex-Situ Viability Assessment by Oxygenated Machine Perfusion.

    N. Karimian,1 V. Huang,1 F. Fontan,1 M. Aburawi,1 S. Geerts,1 S. Mert,1 I. Beijert,2 R. Porte,2 M. Yarmush,1 K. Uygun,1 J. Markmann,1 H. Yeh.1

    1Division of Transplantation, Massachusetts General Hospital, Boston; 2Division of Transplantation, University Medical Center Groningen, Groningen, Netherlands

    Fatty livers are frequently declined for transplantation due to high risk of primary non-function. Ex-situ oxygenated machine perfusion (MP) is superior to static cold storage…
  • 2017 American Transplant Congress

    Impact of Cytokine Gene Polymorphism on Clinical Outcome of Renal Transplantation.

    I. Pérez-Flores,1 J. Santiago,2 A. Moreno Dela Higuera,1 N. Calvo,1 B. Rodriguez-Cubillo,1 E. Urcelay,2 A. Shabaka,1 M. Calvo,1 A. Sanchez-Fructuoso.1

    1Nephrologist, Hospital Clinico San Carlos, Madrid, Spain; 2UGC Immunology, Hospital Clinico San Carlos and Instituto de Investigación Sanitaria (IdISSC), Madrid, Spain

    Cytokine production is subject to genetic regulation, in such a way that gene polymorphisms at the level of promoter or coding regions can alter their…
  • 2017 American Transplant Congress

    Sexual Acquisition of HIV-Infection After Kidney Transplantation: Late Presentation and Potentially Fatal Complications.

    M. Cristelli, M. Ribeiro, D. Santos, M. Mazolin, H. Tedesco-Silva, J. Medina-Pestana.

    Transplant Division, Hospital do Rim-UNIFESP, Sao Paulo, Brazil

    Introduction: Transplantation in patients previously infected with HIV is already well established, and cases of donor infection transmission have already been reported. However late acquisition…
  • 2017 American Transplant Congress

    Full Dose Cyclosporine Permanently Reverses Uncontrolled BK Viremia That Is Refractory to Tacrolimus Minimization.

    A. Caero, M. Shah, D. McKay, J. Kerr, J. Joliat, E. Chatfield, R. Steiner.

    Medicine, UCSD School of Medicine, San Diego, CA

    Latent BK infection is benign and common in transplanted kidneys, but active infection causes viremia and kidney damage. Standard practice is to reduce tacrolimus (TAC)…
  • 2017 American Transplant Congress

    Predictive Value of Pre-Transplant Cross-Match Techniques on Living Donor Kidney Transplant Outcomes.

    M. Meneghini,1 E. Melilli,1 I. Revuelta,3 R. Rajalingam,2 E. Rigol,4 S. Chandran,2 F. Diekmann,3 F. Vincenti,2 J. Cruzado,1 J. Martorell,4 O. Bestard.1

    1Kidney Transplant Unit, Bellvitge University Hospital; IDIBELL, Barcelona, Spain; 2Kidney Transplant Unit, UCSF Medical Centre, SanFrancisco; 3Kidney Transplant Unit, Clinic University Hospital, Barcelona, Spain; 4Immunology Department, Clinic University Hospital, Barcelona, Spain

    Study aim: To investigate the impact of different cross-match techniques and their combination before living-donor kidney transplantation(LDKT) on main clinical outcomes.Methods: Retrospective study including 394…
  • 2017 American Transplant Congress

    C3d Assay Result in Potential Transplant Recipients with HLA-DSA, AHG-CDC CxM Negative and FxM Positive or Negative with Their Potential Donors.

    A. Contreras, A. Casillas, N. Castelan, N. Gonzalez-Tableros, M. Lopez, A. Arvizu, A. De Santiago, J. Alberu, J. Arreola-Guerra.

    Transplantation Department, Instituto Nacional de Ciencias Medicas y Nutricion SZ, Mexico City, Mexico

    Background: In a previous study we searched the association between the flow cytometry cross-match assay (FXM) result and the results obtained in the analysis of…
  • 2017 American Transplant Congress

    Effect of Bone Marrow Derived Mesenchymal Stem Cells on Renal Ischemia-Reperfusion Injury in Rabbit.

    J. Jang, H. Ri, I. Hong.

    Agriculture & Life Science, Pyongyang University of Science & Technology, Pyongyang, Democratic Peoples Republic of Korea

    Background: We succeeded to set up a rabbit model of Ischemia-Reperfusion (I/R) injury to test future candidate substance or plant extract that may have anti-oxidant…
  • 2017 American Transplant Congress

    Evaluation of Immunological States of Patients with Cytomegalovirus Infection After Kidney Transplantation.

    A. Tanaka, K. Ide, Y. Tanaka, K. Ishiyama, M. Ohira, H. Tahara, S. Shimizu, D. Kumar, H. Ohdan.

    Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan

    Background: Generally, it is thought that strong immunosuppression causes cytomegalovirus (CMV) infection after kidney transplantation (KT); thus, physicians often reduce the dose of the immunosuppressant…
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