ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Community Health, Center Proximity, and Liver Transplant Waitlist Mortality.

    R. Lynch,1 K. Ross,1 D. Goldberg,2 R. Patzer.1

    1Surgery, Emory University, Atlanta, GA; 2Medicine, University of Pennsylvania, Philadelphia, PA

    Background: While regional organ availability is frequently discussed in allocation policy, the impact of community-level factors and access to a transplant center on waitlist mortality…
  • 2017 American Transplant Congress

    Pre-Transplant HLA-Specific B Cell Breadth of Reactivity in a Novel Multiplex Bead-Based Assay Predicts Rejection in Kidney Transplant Recipients.

    Z. Ilyas,1 A. Aki,1 A. Tambur,1 P. Heeger,2 M. Ansari.1

    1Northwestern University, Chicago; 2Icahn School of Medicine at Mount Sinai, New York

    Introduction: Recipients with broad sensitization to HLA defined by a high percentage of Panel Reactive Antibodies (PRA) are at higher immunologic risk for poor graft…
  • 2017 American Transplant Congress

    Outcomes with Steroid Avoidance Regimen After Kidney Transplantation without Induction Immunosuppression.

    A. Sakhuja,1 A. Naik,2 D. Cibrik,2 H. Amer.3

    1Medicine - Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN; 2Internal Medicine - Nephrology, University of Michigan, Ann Arbor, MI; 3Medicine - Nephrology and Hypertension, Mayo Clinic, Rochester, MN

    INTRODUCTION: Use of induction immunosuppression therapy at the time of kidney transplantation is variable in low immunological risk kidney transplant recipients. Though acceptable allograft outcomes…
  • 2017 American Transplant Congress

    Absence of Independent and Additional Predictive Ability of Preimplantation Kidney Allograft Biopsies for Long-Term Outcome: Population Based Study.

    O. Aubert, D. Viglietti, C. Loheac, M. Rabant, C. Gosset, J. Duong Van Huyen, D. Glotz, C. Legendre, C. Lefaucheur, A. Loupy.

    Paris Translational Research Center for Organ Transplantation, Paris, France

    BackgroundA significant number of kidneys are discarded worldwide due to the suboptimal use of large kidney resources. The mean cause is the result of the…
  • 2017 American Transplant Congress

    FcγRIIB-Mediated Coinhibition Attenuates Donor-Reactive CD8+ T Cell Responses.

    A. Morris, D. Pinelli, D. Liu, M. Ford.

    Emory Transplant Center, Emory University, Atlanta, GA

    Memory T cells can be a formidable barrier to long-term, rejection-free allograft survival, particularly in the setting of costimulation blockade. Ongoing work in the field…
  • 2017 American Transplant Congress

    Retrospective Analysis of Multiple Hemodialysis Access Modalities.

    V. Bowers,1 H. Pearson,1 J. Huang,1 J. Leone,1 A. Tanious,1 K. Dawley,1 E. Rogers,1 V. Camba,2 C. Albertson,2 D. Lahiff,2 T. Rashid,2 J. Buggs.1

    1Tampa General Hospital, Tampa, FL; 2University of South Florida, Tampa, FL

    The use of native arteriovenous fistulas (AVF) for hemodialysis (HD) is the gold standard, however, for many patients, this is not an option. We hypothesize…
  • 2017 American Transplant Congress

    Donor-Derived Cell-Free DNA Predicts Biopsy-Proven Acute Cellular Rejection in Pediatric Kidney Transplant Recipients.

    D. Stoltz,1 A. Brubaker,1 M. Grskovic,2 R. Woodward,2 A. Gallo.1

    1Surgery, Stanford University, Palo Alto, CA; 2CareDx, Brisbane, CA

    Introduction: Surveillance of allograft health is a critical component of post-kidney transplant care. Invasive protocol biopsies are associated with secondary complications and often provide results…
  • 2017 American Transplant Congress

    Dialysis Facility Providers' Awareness of Racial Disparities in Kidney Transplantation.

    J. Kim, M. Basu, L. Plantinga, C. Escoffery, S. Pastan, R. Patzer.

    Emory University, Atlanta

    Background Racial disparities persist in access to kidney transplant (KTx) in the US, where African Americans (AAs) have lower rates of waitlisting than whites. Despite…
  • 2017 American Transplant Congress

    Inhibition of Liver Natural Killer Cells Activation Through Co-Transplantation of Pre-Activated Mesenchymal Stem Cells Contributes to Improvement of Islet Graft Survival.

    N. Ishida, K. Ishiyama, Y. Saeki, Y. Tanaka, H. Ohdan.

    Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan

    Introduction: We have previously reported that enhancement of TNF-related apoptosis-inducing ligand (TRAIL)-mediated liver NK-cell activity after intraportal islet transplantation (IT) inhibits engraftment of islets. Recently,…
  • 2017 American Transplant Congress

    Immune Sensitization During Pregnancy Reduces Long-Term Benefit for Kidney Recipients of Offspring Living Donors.

    J. Cohen,1 L. Owei,2 D. Sawinski,1 P. Porrett.2

    1Medicine, University of Pennyslvania, Philadelphia, PA; 2Surgery, University of Pennsylvania, Philadelphia, PA

    Background Offspring-to-mother kidney transplantations are associated with excellent short-term outcomes given the accuracy of histocompatibility testing and potency of immunosuppression. However, immunologic memory responses in…
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