2017 American Transplant Congress
Candidate Sex and Size Disparity in Liver Offer Acceptance.
1JHU, Baltimore; 2US Naval Academy, Annapolis
Female liver transplant candidates face lower access to transplantation. Size match between the offered liver and the candidate is important but has not been considered…2017 American Transplant Congress
Center Volume Does Not Influence the Risk Associated with Using High DRI Donor Livers.
Background: High risk donor allografts potentially reduce survival after liver transplantation (LT), but increase access. We evaluated whether differences in patient mortality associated with using…2017 American Transplant Congress
Addition of hEPCR.hCD55.hTFPI.hCD47 Modulates Multi-Lineage Cell Sequestration and Coagulation Activation by GalTKO.hCD46 Transgenic Pig Livers Perfused Ex Vivo with Human Blood.
PurposeThe sequestration of multiple hematopoietic cell lineages and inappropriate coagulation cascade activation is associated with poor outcomes in multiple liver xenotransplant models. Here we evaluate…2017 American Transplant Congress
Higher Mortality Among Candidates Who Refuse to Accept DCD Kidney Offers.
DCD kidneys provide survival benefit but continue to be declined and discarded at elevated rates. We aimed to characterize the potential benefit or harm associated…2017 American Transplant Congress
Outcomes of Organs Transplants When the Donor Is a Prior Recipient.
Introduction: Organ scarcity continues to limit the field of transplantation, which leads to death for patients on waiting lists. Organs from “Organ Donors After Transplant”…2017 American Transplant Congress
Not All Cellular Rejections Are the Same: Differences in Early and Late Hepatic Allograft Rejection.
While acute cellular rejection (ACR) after liver transplantation (LT) is not thought to cause long-term graft injury and inferior outcomes, this notion has been challenged…2017 American Transplant Congress
IL-7 Receptor Heterogeneity as a Mechanism for Repertoire Change During Post-Depletional Homeostatic Proliferation and Its Relation to Costimulation Blockade Resistant Rejection.
Department of Surgery, Duke University School of Medicine, Durham, NC
Transplant patients treated with belatacept without depletional induction show high rates of costimulation blockade resistant rejection (CoBRR); this has been associated with CD57+ T cells.…2017 American Transplant Congress
Presence of Anellovirus Nucleic Acid Sequences in Involved Tissue Is Associated with Worse Patient Survival in Post-Transplant Lymphoproliferative Disorder.
Washington University in St Louis School of Medicine, St. Louis
Introduction: PTLD remain a feared complication of organ and tissue transplant, with high morbidity and mortality. While 50-80% of cases are strongly associated with Epstein-Barr…2017 American Transplant Congress
Dysregulated Innate Immune Response Is a Robust Predictor of Allograft Injury and Survival Across All Transplanted Organs.
ObjectiveLate allograft failure is characterized by long-term cumulative effects of subclinical allograft injury. An optimal biomarker diagnoses acute rejection (AR), correlates with ongoing graft damage,…2017 American Transplant Congress
Identification of Antibody-Mediated Rejection After Kidney Transplantation by Specific MicroRNAs.
Antibody-mediated rejection (ABMR) is the major cause for allograft failure, since a curative therapy is lacking. There are also still challenges in ABMR diagnosis. The…
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