Am J Transplant, Volume 17, Suppl 3 Archives - Page 179 of 181 - ATC Abstracts

2017 American Transplant Congress
Nephrectomy of the Failed First Kidney Allograft Predisposes Kidney Transplant Recipients to Presensitization with Alloreactive T-Cells and Inferior Allograft Survival After Retransplantation.
T. Schachtner,^1,2 M. Stein,¹ P. Reinke.^1,2
¹Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; ²Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany
During the last two decades the number of recipients (KTRs) of a previous kidney transplantation being evaluated and waitlisted for a subsequent kidney transplantation has…
2017 American Transplant Congress
EBV-Specific CD8⁺ T Cells from Pediatric Thoracic vs Abdominal Transplant Recipients Are Shaped Differently by the Chronic EBV Loads with Potential Impact on the Risk of PTLD.
M. Yamada,^1,2 M. Camila,² P. Fadakar,^1,2 K. Hornor,¹ M. Michaels,^1,2 M. Green,^1,2 C. Nguyen,^1,2 B. Feingold,^1,2 G. Mazariegos,^1,2 D. Metes.²
¹Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; ²Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA
Background: EBV infection and post-transplant lymphoproliferative disorders (PTLD) are life-threatening complications of pediatric solid organ transplantation (Tx). Chronic high EBV viral load (HVL) carriers have…
2017 American Transplant Congress
Etiology and Timing of ESRD After Kidney Donation.
A. Matas, D. Berglund, B. Sengupta, H. Ibrahim.
UofMN, Mpls
ESRD after kidney donation may occur because of nephrectomy-induced decreased GFR followed by normal age-related decline, by onset of kidney or systemic disease (e.g., HTN),…
2017 American Transplant Congress
Early Antibody-Mediated Rejection C4d Status Remains a Marker of Prognosis in HLA-Incompatible Kidney Transplantation.
J. Malheiro,¹ S. Santos,¹ S. Tafulo,² L. Dias,¹ L. Martins,¹ J. Ramon,¹ A. Castro-Henriques.¹
¹CHP, Porto, Portugal; ²IPST, Porto, Portugal
Banff criteria for the diagnosis of antibody-mediated rejection (AMR) in kidney transplantation (KT) was recently updated to include the entity of C4d negative AMR, if…
2017 American Transplant Congress
Banff 2013 Classification of Renal Allograft Pathology Is Superior to Banff 2007 in Detecting and Managing Milder and Earlier Cases of Antibody-Mediated Rejection.
J. Hassler,¹ V. Ariyamuthu,² A. Hendricks,¹ B. Tanriover,² J. Torrealba.¹
¹Pathology, University of Texas Southwestern Medical Center, Dallas, TX; ²Medicine, Nephrology, University of Texas Southwestern Medical Center, Dallas, TX
The 2013 Banff meeting updated the requirements for the diagnosis of acute/active antibody-mediated rejection (AAMR) in kidney allografts. There has been speculation that the changes…
2017 American Transplant Congress
Cibinetide (ARA 290), the Innate Repair Receptor Ligand, Improves Engraftment in Pancreatic Islet Transplantation by Protecting Islets and Reducing Inflammatory Reactions.
M. Watanabe,¹ M. Han Yao,¹ H. Zemack,¹ B.-G. Ericzon,¹ A. Cerami,² M. Brines,² T. Lundgren,¹ M. Kumagai-Braesch.¹
¹Department of Transplantation Surgery, CLINTEC, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden; ²Araim Pharmaceuticals, Tarrytown, NY
Purpose. Cibinetide, an innate repair receptor ligand, exerts anti-inflammatory, anti-apoptotic, and cytoprotective effects. We have shown that cibinetide protected mouse pancreatic islets from cytokine-induced damage…
2017 American Transplant Congress
Outcome of ABO-Incompatible Kidney Transplantation After Stratified Desensitization.
K. Nanmoku, A. Kurosawa, T. Kubo, T. Shinzato, T. Shimizu, T. Kimura, T. Yagisawa.
Surgical Branch, Institute of Kidney Diseases, Jichi Medical University Hospital, Shimotsuke, Tochigi, Japan
Background. Plasmapheresis for antibody removal and rituximab for antibody production suppression are performed for desensitization against ABO-incompatible kidney transplantation. We evaluated clinical outcome for optimizing…
2017 American Transplant Congress
Pre-TACE Immune Status Correlates with Treatment Response and Tumor Biology in HCC as a Bridge to Transplant.
T. Sandow,¹ H. Bohorquez,² D. Kirsch,¹ A. Albar,¹ P. Thevenot,³ K. Nunez,³ D. DeVun,¹ J. Gimenez,¹ G. Galliano,⁴ A. Cohen,² G. Loss,² D. Kay,¹ P. Gulotta.¹
¹Radiology, Ochsner Clinic Foundation, New Orleans, LA; ²Transplant Surgery, Ochsner Clinic Foundation, New Orleans, LA; ³Institute of Translational Research, Ochsner Clinic Foundation, New Orleans, LA; ⁴Pathology, Ochsner Clinic Foundation, New Orleans, LA
Purpose:Immune factors are pivotal against disease progression after transplant in hepatocellular carcinoma (HCC). With chemoembolization (TACE) as a bridge to liver transplant, this study compares…
2017 American Transplant Congress
An OPO Offer Acceptance Report for Hard-to-Place Kidneys.
A. Wey, N. Salkowski, B. Kasiske, A. Israni, J. Snyder.
Scientific Registry of Transplant Recipients, Minneapolis, MN
Transplant program offer acceptance behavior varies substantially for kidneys after 100 previous offers (i.e., “hard-to-place offers”). An organ procurement organization (OPO) offer acceptance report could…
2017 American Transplant Congress
Donor Factors Show Low Impact on Patient and Kidney Allograft Outcomes: A Paired Analysis of Left/Right Deceased Donor Kidney Pairs.
T. Schachtner,^1,2,3 M. Stein,² P. Reinke.^1,2
¹Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; ²Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany; ³Charite and Max-Delbrück Center, Berlin Institute of Health BIH, Berlin, Germany
The impact of donor factors on kidney allograft outcomes and infectious complications has been suggested in many previous studies. However, analyses of left/right donor kidney…