ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Beta Cell-Specific Free Circulating DNA May Predict the Outcome After Clinical Islet Transplantation.

    B. Gala-Lopez,1 D. Neiman,2 T. Kin,1 D. O'Gorman,1 A. Pepper,1 A. Malcolm,1 B. Glaser,3 R. Shemer,2 Y. Dor,2 J. Shapiro.1

    1Department of Surgery, Clinical Islet Transplant Program, University of Alberta, Edmonton, AB, Canada; 2Department of Developmental Biology and Cancer Research, The Hebrew University-Hadassah Medical School, Jerusalem, Israel; 3Endocrinology and Metabolism Service, Department of Internal Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel

    Optimizing engraftment and early survival of human beta cells after clinical islet transplantation is critical to long-term function, but there are no reliable, quantifiable measures…
  • 2017 American Transplant Congress

    Kidney Re-Transplant Rate in Simultaneous Kidney Pancreas Transplant Recipients.

    M. McCormick, J. Luo, A. Hoffman.

    Transplant, University of Nebraska Medical Center, Omaha, NE

    Bladder drainage, although no longer the most commonly performed method for exocrine drainage of the pancreas, remains an option for patients undergoing simultaneous pancreas- kidney…
  • 2017 American Transplant Congress

    Surgical Techniques for Pancreas Transplantation Graft without Vascular Reconstruction (Report of 8 Cases).

    A. Hu, W. Liao, C. Zhang, X. Zhu, X. He.

    The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

    Background / Purpose: Pancreas is complicated by its blood supply and vascular structure. At present, it is necessary to do the vascular remodeling and reconstruction…
  • 2017 American Transplant Congress

    In Depth Characterization of the Innate Immune Response in Transplant Recipients with EBV Viremia.

    V. Ferreira, J. Batist, D. Kumar, S. Husain, A. Humar.

    UHN, Toronto, Canada

    Background:Infection with Epstein-Barr virus (EBV) manifests as a spectrum of disease ranging from asymptomatic viremia to PTLD. Innate immune cells such as monocytes/macrophages, dendritic cells…
  • 2017 American Transplant Congress

    Tolerogenic Potential, Migratory Pathways, Engraftment and Long-Term Survival of Human Hematopoietic Chimeric Cells – A Novel Strategy to Induce Tolerance in Transplantation.

    M. Siemionow, E. Bryndza Tfaily, E. Szilagyi, J. Cwykiel, S. Uygur, M. Czerwinski.

    Department of Orthopaedics, University of Illinois at Chicago, Chicago, IL

    Background: Cell-based therapies represent a new promising strategy for tolerance induction in transplantation. One of the methods for immune response modulation in solid organ and…
  • 2017 American Transplant Congress

    Ethylene Carbodiimide Fixed Donor Splenocytes Combined with α-1 Antitrypsin Induce Indefinite Donor Specific Protection to Mice Cardiac Allografts.

    G. Chen, X. Lai, L. Qiu, Y. Zhao, S. Yu, J. Zhang, L. Chen.

    Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    Peritransplant infusion of ethylene carbodiimide fixed donor splenocytes(ECDI-SPs) induces protection of islet and cardiac allografts. However, pro-inflammatory cytokine production during the peritransplantation period may negate…
  • 2017 American Transplant Congress

    Immunoregulatory Roles of CD137 Signaling in Graft-versus-Host Disease.

    H. Cho,1,2 J. Kim,1 B. Kwon,1,3 J. Lee,1,4 K. Park.1,4

    1Biomedical Research Center, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan, Republic of Korea; 2Departments of Surgery, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan, Republic of Korea; 3School of Biological Sciences, University of Ulsan, Ulsan, Republic of Korea; 4Department of Internal Medicine, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan, Republic of Korea

    CD137 functions mainly as a costimulatory molecule for T cell activation. However, its functions have been found in a variety of other immune and nonimmune…
  • 2017 American Transplant Congress

    The Effect of Semimature Dendritic Cell on Transplantation Tolerance of Hepatocytes Differentiated from Mouse Embryonic Stem Cells.

    A. Hu, C. Zhang, W. Liao, X. Zhu, X. He.

    The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

    Objective Research of semimature dendritic cell(smDCs) inducing transplantation toleranceof hepatocytes differentiated from mouse embryonic stem cells (ESCs) and its mechanismtions.Methods Inducing 129 mouse ESCs labelled…
  • 2017 American Transplant Congress

    The Immunophenotype of Peritubular Capillaritis in Renal Transplant Biopsies.

    T. Chen,1 L. Rasch,1 T. Al Johani,2 H. McPhail,1 M. Willicombe,3 A. McLean,3 J. Galliford,3 T. Cook,1 C. Roufosse.1

    1Centre for Complement and Inflammation Research, Imperial College, London, United Kingdom; 2Cellular Pathology, King Saud University, Riyadh, Saudi Arabia; 3Dept Renal Medicine, Imperial College Healthcare NHS Trust, London, United Kingdom

    Background: Peritubular capillaritis (ptc) is a feature of acute antibody-mediated rejection (ABMR) in the renal allograft. However, it is not an specific feature for ABMR…
  • 2017 American Transplant Congress

    Proteins in Preservation Fluid Predict Delayed Graft Function of Kidneys from Donors After Circulatory Death.

    B. van Balkom,1 H. Gremmels,1 L. Ooms,4 R. Toorop,2 F. Dor,5 O. de Jong,1 L. Michielsen,1 G. de Borst,2 W. de Jager,3 A. van Zuilen,1 M. Verhaar.1

    1Nephrology and Hypertension, UMC Utrecht, Utrecht, Netherlands; 2Vascular Surgery, UMC Utrecht, Utrecht, Netherlands; 3Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands; 4Surgery, Erasmus MC, Rotterdam, Netherlands; 5Renal and Transplant Services, Imperial College Healthcare NHS Trust, London, United Kingdom

    Background and objectivesKidney transplantation is the preferred treatment for end-stage kidney disease, and donor kidney shortage urges proper donor-recipient matching. Zero-hour biopsies provide predictive value…
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