2017 American Transplant Congress
Comparing Renal Function Recovery and Long Term Outcomes in Recipients of Standard and Expanded Criteria Donor Kidney Transplants.
McGill University Health Center, Montreal, Canada
Several donor and recipient characteristics are associated with adverse kidney transplantation (KT) outcomes. Our group has previously shown that based on the donor's terminal creatinine,…2017 American Transplant Congress
A Markov Model for Transplant & Renal Outcomes After Liver & Simultaneous Liver-Kidney Transplants.
The Organ Procurement and Transplant Network (OPTN) will implement a set of clinical criteria for simultaneous liver-kidney (SLK) transplant eligibility. Our aim is to build…2017 American Transplant Congress
The Forgotten Element of KAS: A2 to B Transplantation Reduces Waiting Time for Blood Group B Patients by 20%.
Medstar Georgetown Transplant Institute, Washington, DC
Introduction Since the implementation of the Kidney Allocation System (KAS) in 2014 blood group B patients have been able to receive priority for blood group…2017 American Transplant Congress
Uptake of Extracellular Mitochondria Activates Human Endothelial Cells That Stimulate Alloreactive Effector T Cell Responses.
1Surgery, Duke University, Durham, NC; 2Immunology, Duke University, Durham, NC
Introduction: Vascular endothelial cells (VECs), the initial barrier between host immunity and donor allograft tissue, play a critical role in allograft rejection. We investigated the…2017 American Transplant Congress
Current Treatments for Small Hepatocellular Carcinoma: A Network Meta-Analysis of Randomized Controlled Trials.
The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Purpose: Numerous randomized controlled trials (RCTs) concerning treatments for small hepatocellular carcinoma (HCC) have been reported. Herein, we conducted a network meta-analysis integrating current evidence…2017 American Transplant Congress
Precise Antibody Characterization Using Multiple Solid Phase Assay Platforms Is Critical for Accurate Virtual Crossmatching.
Purpose: Virtual crossmatch (VXM) has been utilized in heart transplant (txp) for more than a decade. Many labs base the VXM solely on single antigen…2017 American Transplant Congress
Graft Survival in De Novo Donor-Specific Antibodies and Positive Flow Crossmatch Kidney Transplants Is influenced by Class I and Class II.
Patients with de novo donor-specific antibodies (dnDSA) show inferior graft survival in numerous small studies. We assessed the effect of dnDSA on graft and patient…2017 American Transplant Congress
Infusion of Polyclonal Tregs Modulates Subclinical Kidney Transplant Inflammation: Final Report of TASK Pilot Trial.
Purpose:Treg therapy can reverse established inflammation in animal models. We conducted a pilot safety & feasibility trial of Treg therapy for subclinical kidney transplant inflammation.Methods:Peripheral…2017 American Transplant Congress
Pre-Transplant Circulating TNFR2+ Regulatory T Cells Predict Acute Rejection within the First 6 Months After Kidney Transplantation.
Background: Acute rejection (AR) mostly occurs during the first 6 months after kidney transplantation and contributes importantly to graft loss. Diagnosis relies on changes in…2017 American Transplant Congress
Molecular Analysis of Acute Rejection in Formalin-Fixed Paraffin-Embedded Clinical Face Transplant Biopsies.
1Brigham and Women's Hospital, Boston, MA; 2Harvard T.H. Chan School of Publich Health, Boston
BackgroundDiagnosis of acute rejection in face transplants relies on the histological evaluation of allograft skin biopsies using BANFF classification, an approach with significant limitations including…
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