Am J Transplant, Volume 17, Suppl 3 Archives - Page 170 of 181 - ATC Abstracts

2017 American Transplant Congress
New Approach for Targeted Immunotherapy in Vascularized Composite Allotransplantation.
F. Feturi,¹ H. Wang,² Y. Brudno,² V. Erbas,³ Z. Zhang,³ H. Sahin,³ D. Mooney,² V. Gorantla,³ R. Venkataramanan.¹
¹Department of Pharmaceutical Science, University of Pittsburgh School of Pharmacy, Pittsburgh, PA; ²A Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA; ³Department of Plastic and Reconstructive Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA
Vascularized composite allotransplantation (VCA) have highly immunogenic skin component mandates high doses of systemic immunosuppressive drugs. Oral dosing leads to fluctuating, unpredictable blood levels that…
2017 American Transplant Congress
Steatotic Human Livers Show Inferior Function Compared to Non-Steatotic Livers During Ex-Situ Viability Assessment by Oxygenated Machine Perfusion.
N. Karimian,¹ V. Huang,¹ F. Fontan,¹ M. Aburawi,¹ S. Geerts,¹ S. Mert,¹ I. Beijert,² R. Porte,² M. Yarmush,¹ K. Uygun,¹ J. Markmann,¹ H. Yeh.¹
¹Division of Transplantation, Massachusetts General Hospital, Boston; ²Division of Transplantation, University Medical Center Groningen, Groningen, Netherlands
Fatty livers are frequently declined for transplantation due to high risk of primary non-function. Ex-situ oxygenated machine perfusion (MP) is superior to static cold storage…
2017 American Transplant Congress
Impact of Cytokine Gene Polymorphism on Clinical Outcome of Renal Transplantation.
I. Pérez-Flores,¹ J. Santiago,² A. Moreno Dela Higuera,¹ N. Calvo,¹ B. Rodriguez-Cubillo,¹ E. Urcelay,² A. Shabaka,¹ M. Calvo,¹ A. Sanchez-Fructuoso.¹
¹Nephrologist, Hospital Clinico San Carlos, Madrid, Spain; ²UGC Immunology, Hospital Clinico San Carlos and Instituto de Investigación Sanitaria (IdISSC), Madrid, Spain
Cytokine production is subject to genetic regulation, in such a way that gene polymorphisms at the level of promoter or coding regions can alter their…
2017 American Transplant Congress
Highly Sensitized Patients and the Association of Early Cardiovascular Disease: Analysis of Korean Organ Transplantation Registry(KOTRY) Data.
J. Jeong,¹ J. Yang,² M. Kim,³ S. Shin,⁴ B. Chung,⁵ S. Han,⁶ C. Ahn.⁷
¹Department of Nephrology, Ajou University School of Medicine, Suwon, Korea; ²Transplantation Center, Department of Surgery, Seoul National University Hospital, Seoul, Korea; ³Department of Transplant Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea; ⁴Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; ⁵Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, the Catholic University of Korea, Seoul, Korea; ⁶Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea; ⁷Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
Introduction : In recent studies, immune sensitization was associated with increased mortality in wait-listed kidney transplant candidates. We investigated whether the risk of immune sensitization…
2017 American Transplant Congress
Immunosuppressive Regimen Modification Approaches in BK Nephropathy – A Comparative Study.
H. Ahmed, A. Roche-Recinos, C. Drachenberg, R. Ugarte, N. Costa, M. Mavanur, B. Thomas, A. Haririan.
Department of Medicine, University of Maryland Medical Center, Baltimore, MD
The optimal approach for IS reduction in renal transplant recipients with BKN is not well defined. A number of clinical and in vitro studies suggest…
2017 American Transplant Congress
Impact of Post Kidney Donation Gout on eGFR and Kidney Stones.
B. Sengupta, J. Menk, A. Matas.
Surg, Biostats, UMN, Mpls, MN
Compared to matched non donor controls, living kidney donors have a higher rate of hyperuricemia early post donation (Kasiske,Am J Kidney Dis,2016) and a higher…
2017 American Transplant Congress
The Impact of Marginal Factors on the Postoperative Kidney Function of Complex Living Donors for Kidney Transplantation.
T. Hiramitsu, K. Futamura, M. Okada, M. Tsujita, N. Goto, S. Narumi, Y. Watarai.
Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan
BackgroundMedically complex living donors with marginal factors are increasing.MethodsBetween January 2008 and May 2015, 639 living donors for kidney transplantation were included. Marginal factors for…
2017 American Transplant Congress
A Study on Gene Expression of the Protective Effect of Nitric Oxide Releasing Nanofiber in Rat Renal Ischemia-Reperfusion Injury.
H. Ahn,¹ S. Joo,¹ H. Ko,¹ K. Jung,¹ J. Shin.²
¹Kyung Hee University, Seoul, Korea; ²Kwanwoon University, Seoul, Korea
Objective: Renal ischemia-reperfusion injury (IRI) is very important issue in kidney transplantation. Nitric oxide (NO) was well known to be a protector of IRI. The…
2017 American Transplant Congress
Eight Years of Low-Dose Valganciclovir; Evaluating the Incidence and Risk Factors of CMV in Kidney Transplant Recipients.
S. El Hajj, M. Kim, J. Azzi, S. Gabardi.
Kidney Transplant, Brigham and Women's Hostpial, Boston, MA
Introduction: Cytomegalovirus (CMV) remains one the most clinically relevant and frequent post-transplant infections. Despite the availability of effective antiviral drugs, CMV continues to be of…
2017 American Transplant Congress
Kidney Transplantation in HCV+ Recipients in a New Era of Diagnostics and Therapeutics.
C. Traynor, S. Bumb, C. Berg, M. Ellis, J. Roberts, A. Muir, L. King, C. Brady, S. Sanoff.
Duke University Medical Center, Durham, NC
BackgroundHepatitis-C infected persons (HCV+) evaluated for kidney transplantation receive rigorous staging of their liver disease, often including liver biopsy. Meanwhile, studies have shown that despite…