Am J Transplant, Volume 17, Suppl 3 Archives - Page 168 of 181 - ATC Abstracts

2017 American Transplant Congress
Spiritual and Religious Faith of Actual and Potential Non-Directed (Altruistic) Living Kidney Donors.
A. Maghen,¹ G. Vargas,¹ S. Connor,¹ S. Nassiri,¹ E. Hicks,² L. Kwan,¹ S. Maliski,³ J. Veale.¹
¹Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA; ²Oregon Health and Science University, Portland, OR; ³University of Kansas Medical Center School of Nursing, Kansas City, KS
A. The recent rise in non-directed donors (NDDs) and their initiation of kidney chains offer innovative approaches to help address the overburdened kidney transplant waiting…
2017 American Transplant Congress
Two Months Delayed Induction of Mixed Chimerism After Heart and Kidney Cotransplantation in Nonhuman Primates.
K. Huh,¹ W. Sommer,¹ K. Robinson,¹ X. Wu,¹ J. Paster,¹ I. Hanekamp,¹ A. Dehnadi,¹ T. Kawai,^1,2 R. Smith,³ R. Colvin,^1,3 G. Benichou,¹ J. Madsen.^1,4
¹Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Boston, MA; ²Department of Surgery, Massachusetts General Hospital, Boston, MA; ³Department of Pathology, Massachusetts General Hospital, Boston, MA; ⁴Division of Cardiac Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA
Background We have previously achieved transplant tolerance in cynomolgus recipients cotransplanted with heart and kidney by treating recipients with standard triple drug immunosuppression for 4…
2017 American Transplant Congress
CD4⁺CD28^null T Cells Require IL-15 & IL-21 to Become Alloresponsive.
B. Dedeoglu, N. Litjens, R. Kraaijeveld, W. Verschoor, C. Baan, M. Betjes.
Internal Medicine, Nephrology & Transplantation, Erasmus MC, University Medical Center, Rotterdam, Netherlands
IntroductionAgeing and a pro-inflammatory milieu, such as present in patients with end-stage renal disease, are important drivers of increased T-cell differentiation, which is accompanied by…
2017 American Transplant Congress
CD19⁺CD38^hiCD24^hi Immature Transitional B Cells in PBMCs of Tolerant Kidney Recipients of Facilitating Cell-Enriched Hematopoietic Stem Cells and Renal Allografts.
Y. Wen,¹ A. Merchak,¹ Y. Huang,¹ H. Xu,¹ L. Kahn,¹ J. Leventhal,² S. Ildstad.¹
¹Institute for Cellular Therapeutics, University of Louisville, Louisville, KY; ²Comprehensive Transplant Center, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL
CD19+CD38hiCD24hi immature transitional B cells may represent a biomarker for transplantation tolerance in kidney transplant (KTx) recipients (Cherukuri A, et al. J Am Soc Nephrol.…
2017 American Transplant Congress
The Novel Establishment of Neuroma in Continuity Animal Model Based on Buccal Nerve in Rats.
Y.-H. Hsieh,^1,2 C.-J. Wen,^1,3 C.-H. Lin,^1,2,3,4 F.-C. Wei,^1,2,3 Y.-C. Pei.^3,5
¹Center for Vascularized Composite Allotransplantation, Chang Gung Memorial Hospital, Taoyuan, Taiwan; ²Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan; ³College of Medicine, Chang Gung University, Taoyuan, Taiwan; ⁴Division of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan; ⁵Department of Physical Medicine & Rehabilitation, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Introduction: Peripheral nerve regeneration is a challenging and a rapid growing field. Its application is no longer restricted to trauma reconstruction but also in vascularized…
2017 American Transplant Congress
Life Confocal Imaging of Murine Liver Biopsies as Novel Tool to Assess Graft Viability Prior to Transplantation.
R. Oberhuber, M. Fodor, B. Cardini, M. Maglione, M. Hermann, J. Troppmaier.
Visceral, Transplant and Thoracic Surgery, Medical University Innsbruck, Innsbruck, Austria
Prolonged ischemia time due to organ procurement and transport are main contributors to a decrease in organ quality, which is further enhanced during reperfusion. This…
2017 American Transplant Congress
Preservation Solution Affects the Immunological Milieu in Lung Transplantation and Alters the Inflammatory Balance.
R. Bellmàs Sanz,¹ M. Seyda,¹ B. Wiegmann,² C. Neudoerfl,¹ A. Haverich,^2,3 C. Falk,^1,4 G. Warnecke.^2,3
¹Institute of Transplant Immunology, IFB-Tx, Hannover Medical School, Hannover, Germany; ²Department for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany; ³German Center for Lung Research (DZL), Hannover, Germany; ⁴German Center for Infection Research (DZIF), Hannover, Germany
Background: The pro-/ anti-inflammatory balance in lung transplantation is shaped by the pulmonary immune compartments, i.e. the T and NK cell repertoire. At present, it…
2017 American Transplant Congress
Deciphering the Mechanism of Remote Ischemic Preconditioning and Its Potential Benefits in Ischemia/Reperfusion Injury by Metabolomics.
S. Cho, S.-I. Min, S.-Y. Kim, M.-J. Cho, W. Cho, S. Ahn, S.-K. Min, J. Ha.
Surgery, Seoul National University Hospital, Seoul, Korea
IntroductionRemote ischemic preconditioning (RIPC) is a strategy inducing resistance against ischemia and reperfusion(IR) injury. But the mechanism and the time window of protection representing RIPC…
2017 American Transplant Congress
Pre Transplant Donor Specific Antibodies and Clinical Outcomes in Kidney Transplant Recipient on Steroid Free Maintenance Immunosupression Regimen.
O. Adebiyi,¹ A. Sharfuddin,² M. Yaqub,¹ S. Hussain,¹ D. Mishler,¹ A. Sharfuddin,¹ W. Goggins,¹ T. Taber.¹
¹Renal Transplant, Indiana University School of Medicine, Indianapolis, IN; ²Internal Medicine, Baqai University Hospital, Karachi, Pakistan
Background: The clinical relevance of pre transplant donor specific antibodies has been reported in few clinical studies with respect to its effect on the risk…
2017 American Transplant Congress
A Novel Endpoint for Evaluating the Effect of Everolimus with Reduced Calcineurin Inhibitor on Long-Term Kidney Graft Outcome: The TRANSFORM Study Protocol.
T. Srinivas,¹ C. Legendre,¹ F. Oppenheimer,¹ H. Tedesco-Silva,¹ W.-L. Luo,² P. Bernhardt,² C. Sommerer,¹ S. Chadban,¹ F. Vincenti,¹ J. Pascual.¹
¹TRANSFORM Study Group, Murray; ²Novartis Pharma AG, Basel, Switzerland
Purpose: With the advancement of immunosuppressive (IS) agents, while short-term graft outcomes improved significantly, long-term outcomes remain a concern. Both acute rejection (AR) and nephrotoxicity…