ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Pre-Operative Desensitization for Live Donor Liver Transplantation with Strong Donor-Specific Antibodies.

    M. Fujiki,1 K. Hashimoto,1 A. Zhang,2 F. Aucejo,1 C. Quintini,1 T. Diago,1 B. Eghtesad,1 C. Miller.1

    1General Surgery, Cleveland Clinic, Cleveland, OH; 2Allogen Laboratories, Cleveland Clinic, Cleveland, OH

    Background: Presence of strong donor-specific antibodies (DSA) (MFI>4000) likely results in uncomplicated short-term outcome in whole liver transplants due to absorption of DSA by the…
  • 2017 American Transplant Congress

    Heterotopic Auxiliary Liver Transplantation(ALTx) – Revisited.

    V. Kirchner, E. Minja, S. Chinnakotla, R. Kandaswamy, W. Payne, T. Pruett.

    University of Minnesota, Minneapolis

    Background:Although, ALTx for acute liver failure(ALF) has been described over 30yrs ago, utilization of operation has been limited. Benefit of operation is to provide bridge…
  • 2017 American Transplant Congress

    Is the Time of Appearance and Resolution of De Novo HLA-DP Donor Specific Antibodies Associated with Reduced Deleterious Effect on Lung Transplant Outcomes?

    A. Zhang,1 Y. Sun,2 K. McCurry,3 M. Budev.3

    1Allogen Laboratories, Cleveland Clinic, Cleveland, OH; 2Avalon University School of Medicine, Willemstad, Netherlands Antilles; 3Transplantation Center, Cleveland Clinic, Cleveland, OH

    Introduction: The impact of HLA-DP de novo donor specific antibodies (dDSA) to lung transplantation (LT) is poorly understood. This study analyzed the association of timely…
  • 2017 American Transplant Congress

    Biliary Complications After Pediatric Liver Transplantation: A High Volume Living Donor Liver Transplantation Center Study of 237 Patients Over 27 Years.

    D. Oh,1 N.-J. Yi,1 S. Ahn,1 S. Hong,1 K. Yoon,1 H.-S. Kim,1 H. Kim,1 K.-W. Lee,1 K.-S. Suh,1 J. Han,2 M. Kim,2 J. Lee.2

    1Surgery, Seoul National University College of Medicine, Seoul, Korea; 2Radiology, Seoul National University College of Medicine, Seoul, Korea

    Background. Biliary complication (BC) is prevalent in pediatric liver transplantation (PLT), with reported rates from 12% to 50%. This study analyzed which factors of perioperative…
  • 2017 American Transplant Congress

    Digital Image Analysis of Pediatric Liver Allograft Biopsies Correlates with METAVIR Fibrosis Score.

    R. Fischer,1 S. Foster,2 J. Daniel,1 R. Hendrickson,1 W. Andrews,1 A. Kats.1

    1Children's Mercy Hospital, Kansas City, MO; 2University of Kansas Medical Center, Kansas City, KS

    Background: Serial surveillance biopsies demonstrate post-transplant inflammation and fibrosis in long-surviving pediatric liver allografts. These changes can ultimately lead to cirrhosis and graft failure. However,…
  • 2017 American Transplant Congress

    Systemic Immunosuppression in the Setting of Ocular Surface Stem Cell Transplantation.

    A. Govil,1 A. Cheung,2 E. Sarnicola,2 E. Holland.2

    1University of Cincinnati, Cincinnati, OH; 2Cincinnati Eye Institute, Cincinnati, OH

    Purpose: To evaluate the success, tolerability, and side effects of systemic immunosuppression (SI) in patients undergoing ocular surface stem cell transplantation (OSST) under the SI…
  • 2017 American Transplant Congress

    Prevention of Donor Specific Antibody Production After Skin Allografting by Mobilization of Endogenous Stem Cells Using a Combination of AMD3100 and Low-Dose FK506 in Rats.

    A. Ahmadi,1 L. Qi,1 R. Wesson,1 F. Dor,2 J. Burdik,1 B. Philosophe,1 G. Williams,1 A. Cameron,1 Z. Sun.1

    1Dept. of Surgery, Johns Hopkins University, Baltimore, MD; 2Dept. of Surgery, Imperial College Healthcare, London, United Kingdom

    Background: We have developed a stem cell mobilizing strategy that enables long-term liver and kidney allograft survival without sustained immunosuppression in small and large animals…
  • 2017 American Transplant Congress

    Prediction of Positive Cytotoxic and Flow Crossmatches for Sensitized Wait List Candidates: Comparison of Luminex MFI, C1q and FcR Binding Assays.

    A. Girnita, E. Woodle.

    Surgery, University of Cincinnati, Cincinnati

    Clinical relevance of HLA antibodies identified in solid phase assays includes their ability to generate a positive crossmatch (XM) test, which often precludes transplantation. The…
  • 2017 American Transplant Congress

    Awareness of Change in the Kidney Allocation System Among Dialysis Providers from Facilities with Low Waitlisting.

    M. Basu,1 K. Smith,1 S. Pastan,1 L. Plantinga,1,2 S. Mohan,3 C. Escoffery,2 J. Chung,1 T. Melanson,2 R. Patzer.1,2

    1Emory University School of Medicine, Atlanta, GA; 2Rollins School of Public Health, Atlanta, GA; 3Columbia University, New York, NY

    Background: In December 2014, the new kidney allocation system (KAS) was implemented and is expected to particularly benefit patients who have spent an extended time…
  • 2017 American Transplant Congress

    Neighborhood Poverty and Racial/Ethnic Disparities in Access to Live Donor Kidney Transplantation in the US.

    T. Purnell, X. Luo, D. Crews, S. Bae, L. Kucirka, L. Cooper, D. Segev.

    Johns Hopkins University, Baltimore

    Black transplant candidates have substantially lower rates of live donor kidney transplantation (LDKT) than their White counterparts. We hypothesized that neighborhood poverty might play a…
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