ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Age and Gender Disparities in Post-Lung Transplant Mortality.

    H. Maredia, M. Bowring, A. Massie, S. Oyetunji, C. Merlo, R. Higgins, D. Segev, E. Bush.

    JHU, Baltimore

    Gender, race, and age have been associated with health disparities, including in post-transplant outcomes. Given disparities in post-lung transplant outcomes are not well-understood, we assess…
  • 2017 American Transplant Congress

    Improving Vaccination Rates for Lung Transplant Candidates.

    M. Cortez,1 R. Bag,2 L. Potter.1

    1Pharmacy, The University of Chicago Medicine, Chicago, IL; 2Transplant Center, The University of Chicago Medicine, Chicago, IL

    In 2015, transplant pharmacists at the University of Chicago identified an opportunity to improve vaccination rates for transplant candidates. On 10/1/15, a pharmacist-led program was…
  • 2017 American Transplant Congress

    Variability in Tacrolimus Concentrations Across Pediatric Solid Organ Transplants.

    S. Min,1 T. Daljevic,1 O. Lee,1 M.-E. Alary,6 F. Murdoch,5 R. Parekh,1 V. Ng,1 D. Hebert,1 L. Hamiwka,2 T. Blydt-Hansen,3 V. Phan,4 P. Birk,3 U. Allen,1 S. Urschel,5 CNTRP POSITIVE Research Group, B. Foster,6 S. Mital.1

    1The Hospital for Sick Children, Toronto, Canada; 2Alberta Children's Hospital, Calgary, Canada; 3University of Winnipeg, Winnipeg, Canada; 4Université de Montréal, Motreal, Canada; 5Stollery Children's Hospital, Edmonton, Canada; 6McGill University, Montreal, Canada

    PURPOSE: We characterized the evolution of out-of-range tacrolimus (TAC) concentrations and associated factors during 1 year following a pediatric solid organ transplant (SOT).METHODS: Heart, kidney…
  • 2017 American Transplant Congress

    Distinctive Molecular Features of Antibody-Mediated versus T-Cell Mediated Rejection in Facial Transplantation.

    R. Lopdrup, T. Win, N. Murakami, J. Teague, A. Chandraker, G. Murphy, C. Lian, E. Bueno, B. Pomahac, R. Clark, L. Riella.

    Brigham and Women's Hospital, Boston, MA

    BackgroundA single case of antibody-mediated rejection in a clinical face transplant has been reported worldwide. The availability of repeated allograft biopsies from this patient allowed…
  • 2017 American Transplant Congress

    Thrombalexin and Mirococept Synergistically Reduce IBMIR in a Porcine to Rhesus Xenoislet Model.

    M. Manook,1,2 J. Kwun,1 J. Yoon,1 K. Samy,1 A. MacDonald,1 H. Xu,1 R. Smith,3 A. Dorling,3 A. Kirk,1 N. Mamode,2 S. Knechtle.1

    1Surgery, Duke Transplant Center, Durham, NC; 2Renal and Transplant, Guy's and St Thomas'NHS Foundation Trust, London, United Kingdom; 3MRC Centre for Transplantation, King's College, London, United Kingdom

    Introduction: Early activation of coagulation and complement are important factors in the initiation of instant blood mediated inflammation (IBMIR) in xenoislet models. Two novel 'cytotopic'…
  • 2017 American Transplant Congress

    Differential Suppressive Effects of Costimulatory Blockade (CD28/B7), Anti-IL6R, Bruton's Tyrosine Kinase and Janus Kinase Inhibition on De Novo vs. Recall Alloantibody Responses: Are Combined Drug Therapy Approaches Desirable?

    I. Kim, G. Wu, N.-N. Chai, A. Klein, S. Jordan.

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA

    Purpose: Preformed and de novo donor specific antibodies (DSA) contribute significantly to demise of allograft functions. There is no approved therapies for prevention or treatment…
  • 2017 American Transplant Congress

    Kidney Re-Transplantation (KRTx) from Donation After Cardiocirculatory Death (DCD)-Standard Criteria Donors (SCD).

    M. Khan, B. Alradawna, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, A. Palanisamy, M. Gautreaux, W. Doares, S. Kaczmorsky, R. Stratta.

    Transplant, Wake Forest Baptist Medical Center, Winston Salem, NC

    Donation after cardiac death (DCD) donor kidneys increase the organ pool but use in kidney retransplantation (KRTx) has been questioned due to higher rates of…
  • 2017 American Transplant Congress

    Ethnocultural Barriers to Pre-Emptive Kidney Transplantation: A Single Centre Retrospective Cohort Study.

    A. Bansal, M. Kwok, S. Cao, O. Famure, S. Kim, I. Mucsi.

    University Health Network, Toronto, ON, Canada

    BackgroundPre-emptive kidney transplant (PKT) may offer better outcomes compared to kidney transplant (KT) after starting dialysis. There is a well-documented disparity in access to PKT…
  • 2017 American Transplant Congress

    Health Literacy, Functional Status and Transplant Eligibility Among Adult Liver Transplant Candidates.

    M. Serper, K. Dwinnells, M. Wolf, K. Olthoff.

    University of Pennsylvania, Philadelphia; Northwestern University, Chicago

    Introduction/Objectives: Low health literacy is associated with poor self-care in chronic diseases, however, is understudied in liver transplantation (LT). Study objectives were to evaluate associations…
  • 2017 American Transplant Congress

    The Performance of Four Tools for the Prediction of Potential for Organ Donation After Cardiac Death in Neurocritical Patients: A Prospective, Multicenter, Observational Study.

    Z. Guo,1 G. Xu,1 P. Schroder,2 M. Manyalich,3 X. He,1 G. Chen.1

    1Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; 2Department of Surgery, Duke University Medical Center, Durham; 3Transplant Procurement Management-Donation & Transplantation institute Foundation, Barcelona, Spain

    Background Successful donation after circulatory death (DCD) requires identification of patients dieing within limited time after withdrawal of life-sustaining treatment (WLST). We aimed to compare…
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