ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Comparing Renal Function Recovery and Long Term Outcomes in Recipients of Standard and Expanded Criteria Donor Kidney Transplants.

    S. Sandal, M. Cantarovich, S. Paraskevas, N. Almaghrawi, P. Chaudhury, J. Tchervenkov.

    McGill University Health Center, Montreal, Canada

    Several donor and recipient characteristics are associated with adverse kidney transplantation (KT) outcomes. Our group has previously shown that based on the donor's terminal creatinine,…
  • 2017 American Transplant Congress

    A Markov Model for Transplant & Renal Outcomes After Liver & Simultaneous Liver-Kidney Transplants.

    X. Cheng,1 W. Kim,2 J. Tan,1 J. Goldhaber-Fiebert.3

    1Div Nephrology, Stanford U, Palo Alto; 2Div Gastroenterology & Hepatology, Stanford U, Palo Alto; 3Ctr Health Policy, Stanford U, Palo Alto

    The Organ Procurement and Transplant Network (OPTN) will implement a set of clinical criteria for simultaneous liver-kidney (SLK) transplant eligibility. Our aim is to build…
  • 2017 American Transplant Congress

    The Forgotten Element of KAS: A2 to B Transplantation Reduces Waiting Time for Blood Group B Patients by 20%.

    A. Gilbert, S. Radomski, A. Langeberg, B. Diedrich, S. Rosen-Bronson, D. Li, M. Awwad, M. Grafals, J. Moore, J. Verbesey, P. Abrams, S. Ghasemian, M. Cooper.

    Medstar Georgetown Transplant Institute, Washington, DC

    Introduction Since the implementation of the Kidney Allocation System (KAS) in 2014 blood group B patients have been able to receive priority for blood group…
  • 2017 American Transplant Congress

    Emerging Application of Active Immune Targeted Delivery in Transplantation.

    M. Uehara,1 J. Azzi,1 B. Bahmani,1,2 J. Cheng,3 Q. Yin,3 L. Tang,3 K. Cai,3 Q. Sun,3 M. Kwon,3 Q. Xu,2 G. Brandacher,4 R. Abdi.1

    1Transplantation Research Center/Renal Devision, Brigham and Women's Hospital, Boston; 2Department of Biomedical Engineering, Tufts University, Boston; 3Department of Materials Science and Engineering, University of Illinois at Urbana Champaingn, IL; 4Plastic and Reconstructive Surgery, Johns Hopkins Medicine, Baltimore

    The homing of naïve lymphocytes to the lymph node (LN) is fundamental to the priming of alloreactive T cells. LNs possess highly restricted high endothelial…
  • 2017 American Transplant Congress

    Increasing Liver Transplant Waitlist Dropout for Hepatocellular Carcinoma with Widening Geographical Disparities: Implications for Organ Allocation.

    N. Mehta, M. Sarkar, J. Dodge, R. Hirose, J. Roberts, F. Yao.

    UCSF, San Francisco

    Given the increasing incidence of hepatocellular carcinoma (HCC) and regional differences in liver transplant (LT) rates for HCC, we used the United Network for Organ…
  • 2017 American Transplant Congress

    Trends in the Number and Medical Urgency of Adult Heart Transplant Candidates Listed as Status 1A from 2006-2015.

    W. Parker,1 M. Churpek,1 S. Fedson,2 E. Garrity.1

    1Pulmonary and Critical Care, University of Chicago, Chicago, IL; 2Baylor College of Medicine, Houston, TX

    The wider geographic sharing of hearts in 2006 may have had unintended consequences for transplant center listing behavior. This project examines trends in the number…
  • 2017 American Transplant Congress

    Significant Allosensitisation Despite Early, within 24 Hour, Graft Nephrectomy.

    G. Lucisano,1 P. Brookes,2 E. Santos-Nunez,2 N. Firmin,2 N. Gunby,2 S. Hassan,1 A. Gueret-Wardle,1 M. Willicombe,1 D. Taube.1

    1Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; 2Histocompatibility and Immunogenetics, Imperial College Healthcare NHS Trust, London, United Kingdom

    Introduction: Although it is well known that allograft nephrectomy (Nx) is followed by the development of donor-specific antibodies (DSAs) even after a short transplant period,…
  • 2017 American Transplant Congress

    Acute Cellar Rejection and Long-Term Graft Survival in Pediatric Kidney Transplant Recipients.

    A. Massie, J. Garonzik-Wang, N. Desai, D. Segev.

    JHU, Baltimore

    The association between acute cellular rejection and long-term graft loss among pediatric kidney transplant recipients has not been quantified.Methods: Using SRTR data 2005-2015 and Cox…
  • 2017 American Transplant Congress

    Compartmental Infiltration of Kidney Allograft with Monocyte-Macrophage Subtypes Defines the Type of Rejection.

    T. van den Bosch,1 M. Clahsen-van Groningen,2 F. Rezaee,3 D. Hesselink,1 D. Nieboer,4 E. Steyerberg,4 C. Baan,1 A. Rowshani.1

    1Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands; 2Pathology, Erasmus University Medical Center, Rotterdam, Netherlands; 3Gastroenterology, Erasmus University Medical Center, Rotterdam, Netherlands; 4Public Health, Erasmus University Medical Center, Rotterdam, Netherlands

    Purpose: Rejection significantly worsens the graft function and survival. We studied monocyte-macrophage compartmental infiltration of 62 kidney transplant biopsies with diagnosis of: acute antibody mediated…
  • 2017 American Transplant Congress

    Delayed Tolerance Induction Protocol for Vascularized Composite Allografts in Non-Human Primates: The Immunomodulatory Effect of Donor Bone Marrow Transplantation Does Not Prevent the Development of Chronic Rejection in the Absence of Durable Mixed Chimerism.

    Z. Ng, A. Lellouch, A.-R. Gama, I. Schol, I. Rosales, R. Colvin, L. Geoghegan, J. Kurtz, C. Cetrulo.

    Massachusetts General Hospital, Boston, MA

    PURPOSE: Donor bone marrow transplantation (DBMT) has been investigated in experimental and clinical vascularized composite allotransplantation (VCA). With longer-term follow-up, reports of chronic VCA rejection…
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