ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Neutropenia in Kidney and Liver Transplant Recipients: Risk Factors and Consequences.

    T. Mavrakanas,1 M. Fournier,2 S. Clairou,2 J. Amiel,2 D. Vinh,3 C. Coursol,2 D. Thirion,2 M. Cantarovich.4

    1Medicine, Division of Nephrology, McGill University Health Center, Montreal, QC, Canada; 2Pharmacy, McGill University Health Center, Montreal, QC, Canada; 3Medicine, Division of Infectious Diseases, McGill University Health Center, Montreal, QC, Canada; 4Medicine, Division of Nephrology, Multi-Organ Transplant Program, McGill University Health Center, Montreal, QC, Canada

    Aim: This study aimed to: 1) Define the risk factors associated with neutropenia within the first year post kidney or liver transplantation; 2) Describe the…
  • 2017 American Transplant Congress

    Clinical Utility of Viral miRNA in Urinary Exosomes to Diagnose BK Virus Nephropathy After Kidney Transplantation.

    J.-W. Seo,1 Y. Lee,1 H. Moon,1 Y. Kim,1 K.-H. Jeong,1 J.-Y. Moon,1 C.-D. Kim,2 J. Park,3 B. Chung,4 Y.-H. Kim,5 S.-H. Lee.1

    1Department of Nephrology, Kyung Hee University School of Medicine, Seoul, Republic of Korea; 2Department of Nephrology, Kyungpook National University Hospital, Daegu, Republic of Korea; 3Department of Nephrology, Samsung Medical Center, Seoul, Republic of Korea; 4Department of Nephrology, The St.Mary's Hospital of Catholic University College of Medicine, Seoul, Republic of Korea; 5Nephrology, Inje University College of Medicine, Pusan, Republic of Korea

    Polymerase chain reaction (PCR) demonstration of BK viral replication in plasma and urine supports the diagnosis of BK virus nephropathy (BKVN), an important cause of…
  • 2017 American Transplant Congress

    Benefits of Expanding Options for Patients Registered in the Kidney Paired Donation Program.

    S. Stepkowski, B. Mierzejewska, D. Belbolsynov, C. Baum, J. Kopke, R. Brunner, S. Rees, M. Rees.

    University of Toledo, Toledo, OH

    Introduction: Kidney Paired Donation (KPD) programs play an important role in facilitating exchanges of incompatible donors. We reviewed the outcome of 1121 patients who were…
  • 2017 American Transplant Congress

    Development of an Automatic Regulated Normothermic Kidney Preservation Device for Long-Term Organ Perfusion.

    A. Weissenbacher,1 O. Boubriak,2 L. Lo Faro,1 R. Ploeg,1 J. Hunter,1 D. Voyce,3 N. Mikov,3 A. Cook,3 C. Coussios,2 P. Friend.1

    1Nuffield Department of Surgical Sciences, Oxford Transplant Centre, University of Oxford, Oxford, United Kingdom; 2Department of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom; 3OrganOx Limited, Magdalen Centre, Oxford Science Park, Oxford, United Kingdom

    BackgroundNormothermic kidney perfusion for a period of 24 hours or longer would offer significant clinical advantages. It would enable clinicians to investigate the condition of…
  • 2017 American Transplant Congress

    CMV Infection in Renal Transplant Recipients: Incidence and Efficacy of Prophylaxis According to Cytokine Single Nucleotide Polymorphisms.

    I. Perez-Flores, M. Moreno De La Higuera, N. Calvo Romero, B. Rodriguez Cubillo, A. Shabaka, M. Calvo Arevalo, V. Lopez De La Manzanara, A. Sanchez-Fructuoso.

    Nephrology, Hospital Clínico San Carlos, Madrid, Spain

    Objectives: To evaluate the influence of single nucleotide polymorphisms (SNP)of IL10, TNFα, IFNγand IL18 in the incidence of CMV infection in renal transplant recipients. Methods:…
  • 2017 American Transplant Congress

    Lack of Specificity of LC-MS/MS Based Urinary Biomarkers for Polyomavirus BK Nephropathy (BKPyVN).

    G. Zeng,1 L. Pan,2 Z. Lyu,2 Y. Huang,1 P. Randhawa.1

    1Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA; 2Departments of Nephrology & Pathology, Guangxi Medical University, Nanning, Guangxi, China

    Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) based studies have suggested that BKPyVN leads to the excretion of virus-specific urinary peptides which can serve as diagnostic markers…
  • 2017 American Transplant Congress

    Emerging Variables Which May Enhance Care of HIV Positive Renal Transplant Recipients.

    D. Leonard, M. Prendergast.

    Transplantation, Mayo Clinic, Jacksonville, FL

    Purpose: Single center experience of kidney and pancreas transplantation in the HIV positive populationMethods: Retrospective data and outcomes analysis of HIV positive kidney and pancreas…
  • 2017 American Transplant Congress

    Apoptotic Exosome-Like Vesicles Released During Tissue Injury Trigger IL23/IL-17 Autoimmune Axis and Accelerate Rejection.

    M. Dieudé,1,4 J. Turgeon,1,4 A. Karakeussian-Rimbault,1,4 L. Pomerleau,1 A. Robitaille,1 N. Grandvaux,1 É. Boilard,2,4 M.-J. Hébert.1,3,4

    1Research Centre, Centre Hospitalier de l'Université de Montréal, Montreal, Canada; 2CHU de Québec, Québec, Canada; 3Montreal University, Montreal, QC, Canada; 4Canadian National Transplantation Research Program, Edmonton, Canada

    Autoantibodies to apoptotic antigens, such as perlecan/LG3, are present pre-transplantation and contribute to organ rejection. We previously showed that during tissue injury, apoptotic endothelial cells…
  • 2017 American Transplant Congress

    Trafficking of Donor Leukocytes and Recipient Cells Cross-Dressed with Donor MHC Molecules After Transplantation of Cardiac Allografts in Monkeys.

    J. Marino, K. Robinson, J. Paster, I. Hanekamp, J. Madsen, G. Benichou.

    Center for Transplantation Sciences, Massachusetts General Hospital / Harvard Medical School, Boston, MA

    Activation of recipient T cells recognizing allogeneic MHC molecules displayed on donor leukocytes is known to trigger acute allograft rejection (direct allorecognition). Recently, we have…
  • 2017 American Transplant Congress

    HLA-DPA1 and HLA-DPB1 Frequencies in the US Populations.

    Z. Du, J. Patel, C. Braun, B. Norton.

    Pathology, Loyola University Medical Center, Maywood, IL

    Aim: HLA-DP antibodies can elicit positive crossmatches and be detrimental in organ transplantation. Although HLA-DP unacceptable antigens can be input in the UNOS database, they…
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