Am J Transplant, Volume 17, Suppl 3 Archives - Page 160 of 181 - ATC Abstracts

2017 American Transplant Congress
Higher Tacrolimus Blood Levels Predict Better Graft Survival in Kidney Recipients with De Novo DSA.
M.-A. Béland,¹ R. Noël,¹ I. Côté,¹ I. Lapointe,¹ E. Wagner,² J. Riopel,³ E. Latulippe,³ O. Désy,¹ S. Béland,¹ I. Houde,¹ S. De Serres.¹
¹Renal Division, CHU de Quebec, Laval University, Quebec City, QC, Canada; ²Immunology and Histocompatibility, CHU de Quebec, Laval University, Quebec City, QC, Canada; ³Pathology, CHU de Quebec, Laval University, Quebec City, QC, Canada
Background: De novo anti-HLA donor specific antibodies (dnDSA) are associated with poorer outcomes in kidney transplant recipients. Nonetheless, their monitoring post transplant is not widespread,…
2017 American Transplant Congress
Genomic Analysis of Gene Expression in Human Kidney Transplants Identifies Moxd1 as a Key Driver for Renal Fibrosis.
C. Wei,¹ M. Menon,¹ W. Zhang,¹ C. Woytovich,¹ N. Philippe,¹ J. He,^1,2 B. Murphy,¹ C. Wei.
¹Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY; ²Renal Section, James J Peter Veterans Affairs Medical Center, New York, NY
Chronic allograft injury (CAI), characterized histologically by high chronic allograft dysfunction index (CADI) score on biopsy, is known to be a major determinant of graft…
2017 American Transplant Congress
Is the Current Heart Allocation System Just and Fair for Blood Type O Recipients? – A Propensity-Matched Analysis of 34353 Patients in the UNOS Registry.
M. Ando, K. Takeda, P. Kurlansky, M. Wright, C. Lee, J. Han, A. Garan, V. Topkara, M. Yuzefpolskaya, P. Colombo, M. Farr, Y. Naka, H. Takayama.
Columbia University Medical Center, New York, NY
Purpose: There is a known disparity between the waiting time on heart transplant (HTx) between blood type O and non-O recipients. This difference is mainly…
2017 American Transplant Congress
Dendritic Cell Expression of Rictor (mTORC2), but Not Raptor (mTORC1), Protects Against Renal Ischemia-Reperfusion Injury.
H. Dai,^1,3 N. Rogers,^1,2 A. Watson,¹ D. Fantus,¹ A. Thomson.¹
¹Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; ²Westmead Institute for Medical Research, Sydney, Australia; ³Urologic Organ Transplantation Department, the Second Xiangya Hospital, Central South University, Changsha, China
Background: Dendritic cells (DC) are critical initiators of innate immunity in the kidney and orchestrate inflammation subsequent to ischemia-reperfusion injury (IRI). The mechanistic target of…
2017 American Transplant Congress
Noninvasive Prognostication of Renal Allograft Failure Following BK Virus Associated Nephropathy – A Validation Study.
E. Abuhelaiqa, C. Snopkowski, C. Li, J. Lee, T. Muthukumar, H. Yang, M. Suthanthiran, D. Dadhania.
Transplant Medicine, Weill Cornell Medicine, NY, NY
Introduction. Identification of kidney transplant (KTx) recipients at risk for graft loss following BKVN diagnosis may allow personalization of immunosuppressive protocols. Previous study demonstrated that…
2017 American Transplant Congress
Risk of Ischemic Biliary Injury Is Not Associated with Prolonged Hepatic Artery Ischemic Times During Liver Transplantation.
E. Armenia,¹ N. Schomaker,¹ A. Kalra,¹ J. Gralla,¹ A. Truesdale,¹ S. Biggins,² T. Nydam,¹ J. Burton.¹
¹Univ. Colorado, Aurora, CO; ²Univ. Washington, Seattle, WA
Biliary strictures after liver transplant (LT) are associated with increased patient morbidity and graft failure. AIM: To assess the association of duration of hepatic artery…
2017 American Transplant Congress
Survival Outcomes from DCD Transplant Are Comparable to DBD Transplant from Kidneys Procured from Donors > 50 Years of Age. A UNOS/OPTN Propensity Score Matched Pair Analysis.
H. Sharma, D. Mikhail, J. Chen, B. Al-Harbi, P. Luke, A. Sener.
Multi-Organ Transplant Unit, London Health Sciences Centre, London, ON, Canada
Background:Caution is guarded in accepting offers from old donors due to risk of poor graft function. We aim to present the factors significantly determining the…
2017 American Transplant Congress
Transplant Economics Post Implementation of the Affordable Care Act and the Budget Control Act Sequestration Adjustment on Medicare Reimbursement.
E. Zavala,¹ J. Rogers,² R. Howey,³ S. Karp.¹
¹VUMC, Nashville; ²Tx Mgmt Group, San Diego; ³Mayo Clinic, Jacksonville
Purpose: Adjustments in the Affordable Care Act (ACA) of 2010 and sequestration from the Budget Control Act (BCA) of 2011 have impacted Medicare reimbursement for…
2017 American Transplant Congress
Glomerular CD45 Immunostaining in Post Perfusion Graft Biopsies Predicting Rejection.
A. Yuvaraj, A. Prasad, K. Gopalakrishnan, N. Krishnan.
Renal Transplant Unit, University Hospitals Coventry, Coventry, United Kingdom
Introduction: Recipients of incompatible renal allografts remain at risk of developing AMR after transplantation. Current microarray analysis of allograft biopsies showed similar disturbances in AMR…
2017 American Transplant Congress
Podocyte Participates in the ST2 Related Renal Fibrosis.
Y. Kim,¹ S. Yang,^2,3 R. Cha,⁴ M.-Y. Yu,¹ S. Lee,³ H. Lee,¹ J. Lee,⁵ D. Kim,^1,3 S. Kim,³ Y. Kim.^1,2,3
¹Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; ²Seoul National University Biomedical Research Institute, Seoul, Republic of Korea; ³Kidney Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; ⁴Internal Medicine, National Medical Center, Seoul, Republic of Korea; ⁵Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea
Objective Soluble ST2 (sST2) which is the receptor of IL-33 is involved in renal inflammation and it is also correlated with disease severity in chronic…