2017 American Transplant Congress
Kidney Quality Dramatically Influences Patient and Death Censored Graft Survival in SLK Recipients.
Department of Transplant Surgery, University of Wisconsin, Madison, WI
Introduction: Renal grafts used in simultaneous kidney liver (SLK) transplants are allocated on “center based” arbitrary clinical criteria without entering the kidney allocation algorithm. The…2017 American Transplant Congress
Protease Inhibitor-Based Regimens Are Associated with Inferior Outcomes in HIV-Infected Kidney Transplant Recipients.
1University of Alabama at Birmingham, Birmingham; 2University of Pennsylvania, Philadelphia
Background: Excellent outcomes have been demonstrated among HIV-infected kidney transplant (KT) recipients when HIV infection is well-controlled. Protease inhibitors (PI) have significant drug-drug interactions with…2017 American Transplant Congress
Baseline Immune Assessment to Individualize Immunosuppression in SPK Recipients with Type 1 Diabetes.
Introduction:Type 1 diabetes (T1D) is an immune-mediated disorder associated with multiple immunological anomalies. Immunologic abnormalities might help to explain why recipients of simultaneous pancreas kidney…2017 American Transplant Congress
Role of Donor-Derived Tissue Resident Memory T cells in Modulating Alloimmunity.
Emory Transplant Center, Emory University, Atlanta, GA
Recipient-derived, graft-specific memory T cells play a critical role in mediating allograft rejection, particularly in the setting of immunosuppression with costimulation blockade. Recently, it is…2017 American Transplant Congress
Induction of Mixed Chimerism to Prolong Liver Allograft Survival in Cynomolgus Monkeys.
CCTI, Columbia University, New York, NY
Purpose: Spontaneous liver tolerance occurs in highly selected patients with stable liver function. There is an unmet need for a safe and reliable regimen allowing…2017 American Transplant Congress
High Titer De Novo Donor-Specific HLA Alloantibodies and Cardiac Allograft Vasculopathy After Pediatric Heart Transplantation.
Background: Cardiac allograft vasculopathy (CAV) continues to be a limiting factor in long-term survival after pediatric heart transplantation (HT). Criteria for early diagnosis of CAV…2017 American Transplant Congress
Urinary Retention Associated with Polyomavirus (BK) Viruria and Higher Peak Blood BK Following Kidney Transplant (KTx).
BACKGROUND: BK nephropathy is a major risk factor for allograft dysfunction and loss. BK viruria and viremia are early markers of BK nephropathy in KTx…2017 American Transplant Congress
Impact of Cold Ischemia Time on Outcomes in Kidney Paired Donation (KPD).
1UWHealth, Madison; 2UMN, Minneapolis
Cold ischemic time (CIT) is an established risk factor for delayed graft function (DGF) in DD kidney tx. Impact of prolonged CIT, in the context…2017 American Transplant Congress
Differential Effects of the Novel ATP-Competitive mTOR Inhibitor (TORKinib) AZD2014 and Rapamycin on Alloimmunity and Transplant Survival.
Surgery, Thomas Starzl Transplantation Institute, Pittsburgh, PA
Background: Rapamycin (RAPA), is an immunosuppressive agent that inhibits the mechanistic target of Rapamycin (mTOR), the kinase subunit of two mTOR- containing complexes (mTORC1 and…2017 American Transplant Congress
Vendor to Center in 0-60: A Safe and Effective Blueprint for Creating an In-House On-Call System for Organ Offers.
Transplant, Medical University of South Carolina, Charleston, SC
Introduction: Our center returned to an in-house nurse coordinator on-call program 7/2016 after using a vendor from 11/2012 to 7/2016 for organ allocation. It was…
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