Am J Transplant, Volume 17, Suppl 3 Archives - Page 155 of 181 - ATC Abstracts

2017 American Transplant Congress
Transient High Dose Tacrolimus Allows Tolerance of a Vascularized Composite Allograft Tolerance Across a Full MHC Mismatch.
A. Leto Barone, H. Wang, E. Swanson, K. Kolegraff, J. Lopez, G. Furtmüller, B. Oh, S. Alfadil, S. Mermulla, J. Sacks, S. Bonawitz, G. Raimondi, J. Shores, D. Cooney, W. Lee, G. Brandacher.
Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD
Purpose: The achievement of tolerance in Vascularized composite allografts (VCA) could avoid the risks of immunosuppression in this setting. We investigated strategies for tolerance induction…
2017 American Transplant Congress
Accelerated De-Novo Donor-Specific Antibody-Mediated Rejection in a Non-Human Primate Model of Renal Transplantation.
J. Danobeitia, P. Chlebeck, J. Torrealba, T. Zens, L. Zitur, A. D'Alessandro, L. Fernandez.
Surgery - Division of Transplantation, University of Wisconsin-Madison, Madison, WI
The development of accelerated antibody-mediated rejection (ABMR) is associated with early allograft dysfunction and premature graft loss. In animals, pre-sensitization is usually required in order…
2017 American Transplant Congress
Inhibition of Memory T Cell Alloresponses by TIM-1+ B Cells.
B. Gonzalez-Nolasco, H. Tector, J. Markmann, G. Benichou.
Department of Surgery, Center for Transplantation Sciences, Massachusetts General Hospital/Harvard Medical School, Boston, MA
Background:Alloreactive memory T cells mediate accelerated rejection of allografts and prevent tolerance induction. While regulatory B cells (Bregs) can promote tolerance induction through suppression of…
2017 American Transplant Congress
Kidney Transplantation Outcomes from Donors with Acute Kidney Injury.
S. Channapatna Suresh, M. Lubetzky, J. Graham, A. Chokechanaisakul, O. Mohammed, M. Kinkhabwala, E. Akalin, J. Rocca, P. Bedi.
Abdominal Transplant Surgery, Montefiore Medical Center, Bronx, NY
Background- Organ scarcity and increased waiting times for kidney transplantation has led the transplant community to utilize more sub-optimal organs while continuing providing survival benefit…
2017 American Transplant Congress
Non-Medical Factors Contributing to Racial Disparity in Kidney Transplant Wait-Listing.
Y.-H. Ng,¹ S. Pankratz,¹ K. Bornemann,² E. Croswell,² J. Pleis,² R. Shapiro,³ M. Unruh,¹ L. Myaskovsky.²
¹Medicine, Nephrology, University of New Mexico, Albuquerque, NM; ²Department of Medicine, University of Pittsburgh, Pittsburgh, PA; ³Department of Surgery, Mount Sinai Hospital, New York, NY
Background: African American (AA) and other minorities (OM) are known to have disproportionately higher incidence of end-stage kidney disease (ESKD) but lower rates of kidney…
2017 American Transplant Congress
Are ICD-9 V Codes Representative of the Liver Transplant Wait List?
Y. Bababekov, D. Chang, Y.-C. Hung, J. Adler, S. Stapleton, J. Markmann, H. Yeh.
Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA
Background: Disparities in liver transplantation once wait listed are well-described, but little is known about how and why only 20% of end-stage liver disease patients…
2017 American Transplant Congress
Hepatitis C Genotypes Among Deceased Organ Donors in the United States.
D. Goldberg,¹ V. Van Deerlin,¹ M. Farooqi,¹ A. Sicilia,¹ R. Hasz,² R. Bloom,¹ E. Blumberg,¹ C. Gentile,¹ P. Abt,¹ P. Reese.¹
¹University of Pennsylvania, Philadelphia, PA; ²Gift of Life, Philadelphia, PA
Background: HCV is one of the leading causes of liver disease in the US. 5% of deceased organ donors are HCV+ and HCV infection is…
2017 American Transplant Congress
Hypogammaglobulinemia in Pediatric Heart Transplant Candidates Is Not Corrected by Transplantation.
R. Madan,¹ R. Penkert,² J. Dara,¹ J. Lamour,¹ B. Herold,¹ J. Hurwitz.²
¹Pediatrics, Albert Einstein College of Medicine and The Children's Hospital at Montefiore, Bronx, NY; ²Infectious Diseases, St Jude Children's Research Hospital, Memphis, TN
Introduction: Hypogammaglobulinemia (HG) is associated with poor outcomes in adult heart transplant recipients but is not well studied in pediatric recipients. We therefore investigated longitudinal…
2017 American Transplant Congress
NK Cells Respond to CMV Lysate by Inducing IFNγ and CD107a Surface Expression in an Antibody-Dependent Manner: This Represents a Cytokine Flow Cytometry (CFC) Assay That Could Assess Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) as a Marker of CMV Immunity in Transplant Recipients.
S. Ge, C. Maggie, B.-H. Shin, A. Karasyov, S. Jordan, M. Toyoda.
Transplant Immunology Laboratory and Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
Background: Viral infections represent significant morbidity factors for transplant recipients. Tools to assess the efficacy of viral-specific responses are lacking. ADCC is the major antibody-mediated…
2017 American Transplant Congress
Decision Tree Analysis of Renal Transplantation Recipients Outcomes: A Single Center Data Mining in the Big Data Era.
J. Zhou,¹ Y. Shen,² R. Wang,¹ H. Huang,¹ J. Wu,¹ J. Chen.¹
¹Kidney Disease Center, the First Affiliated Hospital, Zhejiang University, Hangzhou, China; ²Department of Epidemiology, College of Medicine, Zhejiang University, Hangzhou, China
Background This is the era of big data and it may help manage clinical practice better. Decision tree analysis is a useful data mining tool…