Am J Transplant, Volume 17, Suppl 3 Archives - Page 154 of 181 - ATC Abstracts

2017 American Transplant Congress
Serva NB1 versus Vitacyte Collagenase: Comparable Human Islet Isolation Outcomes Using DCD Donor Pancreas in China.
Y. Liu, P. Sun, J. Zou, G. Wang, T. Liu, L. Wang, S. Wang.
Transplant Center, Tianjin First Center Hospital, Tianjin, China
Objective This study was designed to retrospectively compare the effect of Serva NB1 collagenase between Vitacyte collagenase on islet isolation of DCD pancreas in China.…
2017 American Transplant Congress
Predictors of Malignancies Across Solid Organ Transplantation.
M. Bhat,¹ K. Mara,² R. Dierkhising,² K. Watt.³
¹Multi Organ Transplant Program, University Health Network, Toronto, ON, Canada; ²Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN; ³Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN
Background & Aims:Solid organ transplant recipients are at much higher risk of cancer as compared to the general population. The aim of this study was…
2017 American Transplant Congress
IL-33 Enhances the Ability of Dendritic Cells to Expand Human Regulatory T Cells.
Y. Zhao,¹ H. Zhang,¹ L. Mathews,¹ H. Turnquist,^1,2 A. Thomson.^1,2
¹Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA; ²Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA
Introduction:The importance of increasing the number of regulatory T cells (Treg) relative to T effectors for the promotion of long-term experimental allograft survival/tolerance is well-established.…
2017 American Transplant Congress
CD4 and CD8 T Cells: Respectively Reprogrammed and Recapitulated in the Neonate to Induce Transplant Tolerance.
R. Bascom, K. Tao, L. West.
Alberta Transplant Institute, University of Alberta, Edmonton, Canada
Purpose: Non-conditioned neonatal mice develop acute graft-versus-host disease (aGVHD) when injected with adult allogeneic spleen and bone marrow cells (allo-SC/BMC). To prevent aGVHD and induce…
2017 American Transplant Congress
The Impact of Tracheal Epithelial Cells Apoptosis on the Biological Behavior of Bone Marrow Mesenchymal Stem Cells (BMSCs) in OB.
X. Zhang,¹ T. Xia,² C. Wang,² K. Jiang,² J. Wang,² J. Nie.²
¹Department of Integrative Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China; ²Department of Thoracic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China
Background: During the development of obliterative bronchiolitis (OB), extensive extracellular matrix is deposited in the lumen of the bronchioli, and the number of myofibroblasts increases.…
2017 American Transplant Congress
Technically Successful Miniaturization of Blood Hemofilters for an Artificial Kidney via Bioengineering Techniques.
R. Forbes,¹ C. Kensinger,¹ S. Karp,¹ J. Groszek,¹ A. Buck,² D. Colvin,² S. Roy,³ W. Fissell.¹
¹Vanderbilt University Medical Center, Nashville; ²Institute of Imagine Science, Vanderbilt University, Nashville; ³University of California San Francisco, San Francisco
Background: Creating flow channel pathways for an implantable artificial kidney with minimal risk of thrombosis is particularly difficult when miniaturizing into a multilayer bio-hybrid device.…
2017 American Transplant Congress
Rejection of Human Kidney Allografts According to BANFF Classification Is Associated with a Chemokine-Enriched Protein Microenvironment in Biopsy Tssue.
C. Falk,¹ K. Daemen,¹ J. Keil,¹ F. Lehner,² H. Haller,³ J. Schmitz,⁴ J.-H. Bräsen,⁴ C. Blume.⁵
¹Institute of Transplant Immunology, IFB-Tx, Hannover Medical School, Hannover, Germany; ²Department of Abdominal, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany; ³Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany; ⁴Institute of Pathology, Hannover Medical School, Hannover, Germany; ⁵Institute for Technical Chemistry, Leibniz University, Hannover, Germany
Background: Expression profiling efforts of biopsy tissue after kidney transplantation indicate that rejection can be defined by distinct signatures. Based on pathological evaluation (BANFF) as…
2017 American Transplant Congress
PPAR-γ Agonist Attenuates Hepatic Ischemia-Reperfusion Injury in a Mouse Model by Regulating Kupffer Cell Polarization.
I. Linares, K. Farrokhi, J. Echeverri, M. Kaths, D. Kollman, M. Hamar, P. Urbanellis, S. Ganesh, O. Adeyi, P. Yip, N. Selzner, M. Selzner.
Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada
PPAR-γ agonists have shown protective effect on ischemia-reperfusion injury (IRI) in cerebral and renal tissue. The effects of PPAR-γ on hepatic IRI is unclear. We…
2017 American Transplant Congress
Conversion from Tacrolimus-Based to Everolimus-Based Immunosuppressive Therapy 3 Months After Living-Donor Kidney Transplantation: A Randomized-Controlled Clinical Trial.
D. Hesselink,¹ N. Shuker,¹ J. Osinga,¹ M. Clahsen -van Groningen,² J. Damman,² C. Baan,¹ J. van de Wetering,¹ A. Rowshani,¹ J. Kal -van Gestel,¹ W. Weimar,¹ T. van Gelder,³ R. Bouamar.³
¹Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands; ²Pathology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands; ³Hospital Pharmacy, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands
While conversion from ciclosporin to everolimus is well documented, conversion from tacrolimus has been poorly studied. In this randomized-controlled trial the safety and tolerability of…
2017 American Transplant Congress
Effect of Everolimus-Based Regimen on Graft Outcomes in Kidney Transplant Recipients with Diabetes at Baseline: Post-Hoc Analysis from the ELEVATE Study.
J. de Fijter,¹ H. Holdaas,¹ J. Sanders,¹ S. Sundar,¹ F. Bemelman,¹ P. Lopez,² G. Bader,² J. Cruzado,¹ M. van der Giet.¹
¹ELEVATE Study Group, Leiden, Netherlands; ²Novartis Pharma AG, Basel, Switzerland
Purpose: Presence of diabetes may have adverse impact on graft outcome in kidney transplant recipients (KTxRs). This post-hoc analysis from the ELEVATE study compared the…