ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Development of Transplant Glomerulopathy in Recipients with Antibody Mediated Rejection: Activation of Inflammatory Pathway Through Renal Poly (ADP-Ribose) Polymerase (PARP).

    B. Ozdemir,1 F. Ozdemir,2 E. Baskin,2 M. Haberal.3

    1Pathology, Baskent University, Ankara, Turkey; 2Pediatric Nephrology, Baskent University, Ankara, Turkey; 3Transplant Surgery, Baskent University, Ankara, Turkey

    Activation of PARP is a critical factor in the pathogenesis of various inflammatory and fibrotic process. Thus we aimed to show the integral of PARP…
  • 2017 American Transplant Congress

    C-C Chemokine Receptor 5 Polymorphisms and Risk of Antibody-Mediated Rejection in Renal Transplantation.

    J. Lee,1 D. Kim,1 J. Lee,1 S.-K. Kwon,1 S. Song,1 J. Lee,1 B. Kim,2 M. Kim,1 S. Kim,1 Y. Kim,1 K. Huh.1

    1Transplantation Surgery, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea; 2Nephrology, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea

    Antibody-mediated rejection (AMR) is the leading cause of graft failure after kidney transplantation. C-C Chemokine receptor 5 (CCR5) plays an important role in immune cell…
  • 2017 American Transplant Congress

    Incidence and Clinical Outcomes of Active Tuberculosis in Transplant Recipients from a Low Prevalence Region.

    Y. Natori, A. Humar, S. Husain, D. Kumar.

    Multi-Organ Transplant Program, UHN, Toronto, Canada

    Background: Tuberculosis (TB) is a significant opportunistic infection in solid organ transplant recipients (SOTR). Therapy for TB is complex in this population due to drug…
  • 2017 American Transplant Congress

    Efficacy of Trimethoprim-Sulfamethoxazole Prophylaxis for Nocardia in Solid Organ Transplant Recipients (SOTRs): Systematic Review and Meta-Analysis.

    A. Alsharidi,1 A. Gonzalez,2 C. Rotstein,3 A. Humar,3 D. Kumar,3 S. Husain.3

    1Medicine, Infectious Diseases, McMaster University, Hamilton, ON, Canada; 2Medicine, Infectious Diseases, University of Florida, Gainesville, FL; 3Multi-Organ Transplant, Transplant Infectious Diseases, University of Toronto, Toronto, ON, Canada

    Background:There are increasing reports of breakthrough Nocardia infection in patients taking Trimethoprim-Sulfamethoxazole (TMP-SMX) prophylaxis post SOT. We performed a meta-analysis to evaluate the effectiveness of…
  • 2017 American Transplant Congress

    Extended Ex Vivo Kidney Perfusion Using Hemopure as an Oxygen Carrier: A Method to Preserve, Assess and Repair Discarded Organs.

    F. Fontan, M. Aburawi, N. Karimian, K. Uygun, F. Delmonico, H. Yeh, J. Markmann.

    Transplant Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background: Hypothermic non-oxygenated machine perfusion (HMP) is commonly used in kidney preservation, providing some advantage over static cold storage, as well as flow and resistance…
  • 2017 American Transplant Congress

    Longer Anastomotic Time Leads to Delayed Graft Function.

    M. Heer,1,2 P. Trevillian,1,2,3 A. Hibberd.1,2,3

    1Newcastle Transplant Unit, John Hunter Hospital, Newcastle, NSW, Australia; 2Newcastle University, Newcastle, NSW, Australia; 3Hunter Transplant Research Foundation, Hunter Medical Research Institute, Newcastle, NSW, Australia

    Background: Delayed graft function (DGF) occurs at variable rates in renal transplant recipients. It can be deleterious to renal allograft in long term. Various factors…
  • 2017 American Transplant Congress

    Significance of Thrombotic Microangiopathy in Renal Allografts.

    B. Ozdemir,1 A. Ok Atilgan,1 M. Haberal.2

    1Pathology, Baskent University, Ankara, Turkey; 2Transplant Surgery, Baskent University, Ankara, Turkey

    Thrombotic microangiopathy (TMA) in the renal allograft is a form of renal capillary injury that may associate with many disorders including calcineurin inhibitor (CI) toxicity,…
  • 2017 American Transplant Congress

    Impact of Induction Immunosuppression on the Recurrence of Primary IgA Nephropathy.

    K. Lee, C. Cho, N. Lee, K. Kim, S. Kim, J. Lee, J. Lee, H. Park, J. Park, S. Kim.

    Department of Surgery, Samsung Medical Center, Seoul, Korea

    PurposeIgA nephropathy (IgAN) may recur after kidney transplantation (KT) and potentially jeopardize the survival of the graft. The object of this study was to analyze…
  • 2017 American Transplant Congress

    Induction Immunotherapy in ECD and DGF Kidneys: Does ECD Equal Diminishing Induction Returns?

    M. Barrett, A. Smith, K. Woodside, R. Sung.

    University of Michigan, Ann Arbor

    The benefit of induction immunotherapy to prevent DGF or mitigate its effects in recipients of marginal kidneys is not well understood and practices vary. We…
  • 2017 American Transplant Congress

    Identifying Independent Risk Factors for Graft Loss After Primary Liver Transplantation: A Propensity Score Matched Analysis.

    J. Gwiasda, H. Schrem, A. Kaltenborn.

    Core Facility Quality Management Transplantation, Hannover Medical School, Hannover, Germany

    This study aims to identify independent risk factors for graft loss after primary liver transplantation beyond the occurrence of hepatic artery thrombosis. Graft loss was…
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