2017 American Transplant Congress
Causes and Long-Term Consequences of Diarrhea After Kidney Transplantation.
BackgroundThe causes and effects of diarrhea on graft outcomes have been poorly investigated in a large cohort of well-phenotyped kidney transplant recipients (KT). The epidemiological…2017 American Transplant Congress
MELD-Based Allocation Leads to Inferior Survival After Liver Transplantation.
Department of Surgery, Campus Virchow and Mitte, Charité-Universitätsmedizin Berlin, Berlin, Germany
Introduction and BackgroundThe MELD-based allocation system has been implemented in Germany in 2006 in order to decrease waiting list mortality in patients with end stage…2017 American Transplant Congress
Risk Factors for Post-Transplant Lymphoproliferative Disorders in Epstein-Barr Virus Mismatch Lung Transplant Recipients.
Brigham and Women's Hospital, Boston
Background: Post-transplant lymphoproliferative disorders (PTLD) are associated with significant morbidity and morality. Lung transplant patients appear to have higher rates of PTLD than other solid…2017 American Transplant Congress
Lessons Learned from Simultaneous Biopsies of Both Kidney and Pancreas Grafts in Recipients of Simultaneous Kidney-Pancreas Transplants.
University of Wisconsin, Madison
It is commonly assumed that in simultaneous kidney and pancreas (SPK) recipients the rejection of the two organs will be concordant. As a result, simultaneous…2017 American Transplant Congress
Regulation of T Cell Migration by Specifically Targeting Lymphotoxin β Receptor (LTβR)-Mediated Non-Canonical NFkB Signaling.
Background:Selective recruitment of regulatory T cells (Treg) to draining lymph nodes is crucial for graft survival, and LTαβ-LTβR signaling is required to direct Treg into…2017 American Transplant Congress
Induction of Delayed Renal Allograft Tolerance Using Only Clinically Available Reagents in Non-Human Primates.
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA
Background: We have previously reported successful induction of renal allograft tolerance following a period of conventional immunosuppression (Delayed tolerance) using nonmyeloablative conditioning that included anti-CD154…2017 American Transplant Congress
Validation of a Prediction Model for Cardiac Allograft Vasculopathy.
Cedars-Sinai Heart Institute, Los Angeles
Introduction: Cardiac allograft vasculopathy (CAV) continues to limit the long-term success of heart transplantation. Although the progression of CAV can be slowed by tailored immunosuppression,…2017 American Transplant Congress
Repeat Biopsies After the Diagnosis of BK Virus Associated Nephropathy: Importance of Integrating Clinical and Pathological Findings.
Early diagnosis of PV nephropathy(PyVAN) leads to overall improvements in the short term but sclerosing sequelae and risk for rejection (mainly antibody mediated) contribute to…2017 American Transplant Congress
Apolipoprotein L1 & Chronic Kidney Disease Risk in Young Potential Living Kidney Donors.
Background: Living kidney donor selection practices have evolved from examining individual risk factors to a risk calculator incorporating multiple characteristics. Due to limited long-term data…2017 American Transplant Congress
Binding of Antigens by Its Specific Antibodies Results in Exosome Formation Leading to Rejection of Syngeneic Murine Cardiac Grafts.
Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix
Background: Antibody binding to its antigen can activate complement cascades leading to cell death. In addition, it can activate intracellular signals leading to rejection of…
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