ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Donor Lymphoid Chimerism in Early Recognition and Prediction of Clinical Outcome Caused by Acute Graft versus Host Disease After Solid Organ Transplant.

    A. Zhang,1 Y. Sun,2 K. Hashimoto,4 M. Fujiki,4 M. Askar,3 J. Fung,5 C. Miller,4 K. Abu-Elmagd,4 B. Eghtesad.4

    1Cleveland Clinic, Allogen Laboratories, Cleveland, OH; 2Avalon University School of Medicine, Willemstad, Netherlands Antilles; 3Baylor University Medical Center, Dallas, TX; 4Transplantation Center, Cleveland Clinic, Cleveland, OH; 5Transplantation Center, University of Chicago, Chicago, IL

    Introduction: Acute graft versus host disease (aGvHD) after solid organ transplant (SOT) is rare but related with high mortality. Early accurate diagnosis is critical for…
  • 2017 American Transplant Congress

    Three Year Outcomes Following Positive Crossmatch Renal Transplantation Despite Failure to Convert to Negative Flow Crossmatch After Desensitization.

    S. Patel,1 J. Benken,1 S. Akkina,3 P. West-Thielke,2 J. Thielke,1 M. Campara,1 J. Oberholzer,2 E. Benedetti.2

    1Pharmacy, University of Illinois Hospital & Health Sciences System, Chicago; 2Surgery, University of Illinois Hospital & Health Sciences System, Chicago; 3Medicine, Loyola University Health System, Maywood

    Purpose: To determine outcomes of positive crossmatch (PXM) renal transplant recipients that failed to convert to a negative flow cytometry crossmatch (FCXM) despite desensitization. Methods:…
  • 2017 American Transplant Congress

    Different Prognostic Factors for Early and Late Recurrence After Adult Living Donor Liver Transplantation for Hepatocellular Carcinoma.

    S. Hong, K.-W. Lee, H.-S. Kim, S.-W. Ahn, K. Yoon, H. Kim, N.-J. Yi, K.-S. Suh.

    Surgery, College of Medicine, Seoul National University, Seoul, Republic of Korea

    Recurrence after liver transplantation (LT) for hepatocellular carcinoma (HCC) remains unsatisfactory. However, some patients with HCC recurrence after LT show good long-term survival results. The…
  • 2017 American Transplant Congress

    Expanded Criteria for HCC in Liver Transplantation.

    M. Haberal,1 A. Akdur,1 G. Moray,1 G. Arslan,2 F. Ozcay,3 H. Selcuk,4 H. Ozdemir.5

    1General Surgery and Transplantation, Baskent University, Ankara, Turkey; 2Anesthesiology, Baskent University, Ankara, Turkey; 3Pediatric Gastroenterology, Baskent University, Ankara, Turkey; 4Gastroenterology, Baskent University, Ankara, Turkey; 5Pathology, Baskent University, Ankara, Turkey

    Introduction: Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and the third highest cause of death related to malignancy. Since HCC diagnosis is…
  • 2017 American Transplant Congress

    Outcome of Kidney Transplantation from Deceased Octogenarian Donors.

    P. Donato, L. Furian, C. Silvestre, F. Neri, C. Di Bella, M. Di Bello, P. Rigotti.

    Kidney and Pancreas Transplantation Uniti, Padua University Hospital, Padua, Italy

    In order to expand the donor pool, the utilization of kidneys otherwise discarded because of extremely old age or comorbidities has been evaluated.We retrospectively analyzed…
  • 2017 American Transplant Congress

    Identification of Kidney Transplant Patients at Risk for Skin Cancer by Differentially Methylated Regions in T Cells.

    F. Peters,1 A. Peeters,1 P. Mandaviya,2 J. van de Wetering,1 M. Betjes,1 C. Baan,1 K. Boer.1

    1Nephrology and Transplantation, Erasmus MC, University Medical Center, Rotterdam, Netherlands; 2Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, Netherlands

    Skin cancer, specifically cutaneous squamous cell carcinoma (cSCC), is the most often occurring malignancy in patients after organ transplantation, with an incidence of 100-200 times…
  • 2017 American Transplant Congress

    Testing the Efficacy of Contrast Enhanced Ultrasound in Detecting Transplant Rejection Using a Murine Model of Heart Transplantation.

    K. Fisher,1 M. Uehara,2 S. Ohori,2 C. Meral,1 S. Giannini,3 T. Ichimura,2 N. Smith,4 F. Jolesz,1 I. Guleria,2 Y. Zhang,1 P. White,1 N. McDannold,1 K. Hoffmeister,3 M. Givertz,5 R. Abdi.2

    1Department of Radiology, Focused Ultrasound Laboratory, Brigham and Women's Hospital/ Harvard Medical School, Boston; 2Transplantation Research Center/Renal Devision, Brigham and Women's Hospital/ Harvard Medical School, Boston; 3Hematology Division, Department of Medicine, Brigham and Women's Hospital/ Harvard Medical School, Boston; 4Department of Pathology, Massachusetts General Hospital/ Harvard Medical University, Boston; 5Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital/ Harvard Medical School, Boston

    One of the key unmet needs to improve long-term outcomes of heart transplantation is to develop accurate, non-invasive and practical diagnostic tools to detect transplant…
  • 2017 American Transplant Congress

    Tacrolimus Suppresses Calcineurin Activity and Ca2+ Influx Age-Specifically.

    F. Krenzien,1,2 M. Quante,1 H. Uehara,1 R. Abdi,1 H. Cetina Biefer,1 M. Schmelzle,2 J. Pratschke,2 A. Elkhal,1 S. Tullius.1

    1Transplant Surgery Research Laboratory and Division of Transplant Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston; 2Department of Surgery, Campus Virchow-Klinikum and Campus Mitte, Charité-Universitätsmedizin Berlin, Berlin, Germany

    Immunosenescence is impacting alloimmunity and outcomes after organ transplantation. Age-dependent effects of immunosuppressants, however, have not been tested sufficiently. Here, we tested the effects of…
  • 2017 American Transplant Congress

    Nafamostat Mesilate Ameliorates Ischemia-Reperfusion Renal Injury via Anti-Apoptotic Mechanism.

    D. Choi,1 J. Jeong,2 H. Bae,1 Y. Ham,1 K. Lee,1 K. Na.1

    1Chungnam National University, Nephrology, Daejeon, Korea; 2Chungnam National University, Department of Medical Science, Daejeon, Korea

    Purpose: It has been reported that nafamostat mesilate inhibits inflammatory injury via inhibition of complement activation in ischemic heart, liver, and intestine. However, it is…
  • 2017 American Transplant Congress

    Course and Outcome of Renal Transplant Recipients Admitted to the Intensive Care Unit (ICU): Long Term Follow-Up.

    A. El-Agroudy,1 A. Alqahtani,1 B. Dandi,2 E. Farid,2 A. Alaradhi.2

    1Medicine, Arabian Gulf University, Manama, Bahrain; 2Nephrology, Salmaniya Medical Complex, Manama, Bahrain

    Background. The goal of this study was to evaluate the course and outcome of renal transplant recipients admitted to ICU and to analyze factors determining…
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