Am J Transplant, Volume 17, Suppl 3 Archives - Page 136 of 181 - ATC Abstracts

2017 American Transplant Congress
Barriers and Experiences When Patients Decide on a Kidney Transplant Center.
C. Schaffhausen,^1,4 M. Bruin,³ J. Synder,^2,4 B. Kasiske,^1,4 A. Israni.^1,2,4
¹Department of Medicine, Hennepin County Medical Center, University of Minnesota, Minneapolis, MN; ²Department of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN; ³College of Design, University of Minnesota, Minneapolis, MN; ⁴Minneapolis Medical Research Foundation, Minneapolis, MN
Choosing a transplant center is one decision in a long pre-transplant process facing many patients. Qualitative studies have previously been used to better understand the…
2017 American Transplant Congress
Characterization of a B Lymphocyte Signature Predictive of Chronic Lung Allograft Dysfunction.
C. Brosseau,^1,2 M. Durand,^1,2 E. Durand,^1,2 J. Loy,² A. Foureau,² P. Lacoste,² P.-J. Royer,² A. Magnan,² S. Brouard.¹
¹INSERM UMR1064, Centre de Recherche en Transplantation et, Nantes, France; ²INSERM UMR1087, Institut du Thorax, Nantes, France
The occurrence of chronic lung allograft dysfunction (CLAD) is the main complication after lung transplantation (LT) and remains the most common cause of graft failure…
2017 American Transplant Congress
Pre-Transplant CMV-Specific T-Cell Immunity Is an Additional Independent Variable Predicting CMV Infection After Kidney Transplantation.
E. Crespo,¹ M. Jarque,¹ S. Luque,¹ E. Melilli,² A. Manonelles,² S. Gil-Vernet,² J. Cruzado,² J. Grinyó,² O. Bestard.²
¹Nephrology Laboratory, IDIBELL, Barcelona, Spain; ²Kidney Transplant Unit, Bellvitge University Hospital, Barcelona, Spain
Background: Current pre-transplant risk stratification for Cytomegalovirus (CMV) infection is based on donor/recipient (D/R) IgG-serostatus and clinical variables such as the use of T-cell depletion…
2017 American Transplant Congress
CMV-Infected Kidney Grafts Drive the Expansion of Blood-Born CMV-Specific T-Cells Restricted by Shared HLA Molecules Through Presentation on Donor's Cells.
P. Gatault,^1,2 S. Al-Hajj,¹ J. Noble,^1,2 E. Chevallier,^1,2 M. Piollet,¹ C. Forconi,¹ R. Lemoine,¹ J.-M. Halimi,^1,2 M. Büchler,^1,2 C. Baron.^1,2
¹EA 4245, François-Rabelais University, Tours, France; ²Kidney Transplantation Department, CHRU, Tours, France
Background. Cytomegalovirus specific immune response is crucial to control CMV infection in kidney transplant recipients (KTR), in whom recipient CMV can reactivated (R+) and donor…
2017 American Transplant Congress
More Rapid Decline in Male VS Female Living Kidney Donations (LKD) Varies by Income.
J. Lesage, J. Gill, C. Rose, Y. Joffres, J. Gill.
UBC, Vancouver, Canada
Reasons for the decline in LKD remain uncertain. We hypothesized that there would be a more rapid decline in male vs female LKD and that…
2017 American Transplant Congress
Personalizing Immunosuppression with Molecular Phenotyping in Pediatric Liver Transplantation.
M. Ningappa, C. Ashokkumar, Q. Sun, B. Higgs, K. Soltys, G. Bond, G. Mazariegos, R. Sindhi.
Pediatric Abdominal Transplant, Children's Hospital of Pittsburgh of UPMC, Pittsburgh
Background: Optimizing immunosuppression requires selecting an agent which can inhibit the dominant anti-rejection mechanism in individual children with liver transplantation (LTx). Extended use of steroids,…
2017 American Transplant Congress
Educational Strategies for Increased Wait-Listing Rates: Opportunities for Dialysis Center Intervention.
A. Waterman,¹ J. Peipert,¹ H. Xiao,² C. Goalby,¹ K. Lentine.²
¹UCLA, Los Angeles, CA; ²SLU, St. Louis, MO
Dialysis centers vary in how well they educate patients about kidney transplant (KT). This study categorized common groups of educational strategies used by dialysis staff;…
2017 American Transplant Congress
Characterization of Human Plasma Cell Proteasome Adaptations to Proteasome Inhibitor Therapy: A Precision Medicine Approach to Overcome Drug Resistance in Desensitization.
J. Driscoll,¹ S. Tremblay,¹ P. Brailey,¹ A. Girnita,¹ R. Alloway,¹ B. Aronow,² H. Singh,² E. Woodle.²
¹U of Cincinnati, Cincinnati, OH; ²Cincinnati Children's, Cincinnati, OH
Purpose: Bone marrow niche-resident plasma cells (BMNRPCs) exhibit variable sensitivity to proteasome inhibitor (PI) therapy. Here, we characterized alterations in the gene and protein expression…
2017 American Transplant Congress
Venous Thromboembolism and the Risk of Death and Graft Loss in Kidney Transplant Recipients.
N. Lam,¹ A. Garg,² G. Knoll,³ J. Kim,⁴ K. Lentine,⁵ E. McArthur,⁶ K. Naylor,⁶ S. Bota,⁶ M. Sood.³
¹University of Alberta, Edmonton, Canada; ²Western University, London, Canada; ³University of Ottawa, Ottawa, Canada; ⁴University of Toronto, Toronto, Canada; ⁵Saint Louis University School of Medicine, St. Louis; ⁶Institute for Clinical Evaluative Sciences, London, Canada
Background: The incidence of venous thromboembolism (VTE) in kidney transplant recipients varies widely in the literature. The implications of VTE for morbidity and mortality in…
2017 American Transplant Congress
Improving Liver Allocation Using Optimized Neighborhoods.
S. Mehrotra, V. Kilambi.
Industrial Engineering and the Management Sciences, Northwestern University, Evanston, IL
Background: Geographic disparities persist in access to liver transplantation. Candidates with similar urgency experience varying opportunities for transplants across the US. Policymakers are poised to…