ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    A Kidney Paired Donation Standard Acquisition Charge.

    M. Rees,1,2 L. Reece,2 S. Rees,2 B. Crandall,3 A. Leichtman.4

    1U of Toledo, Toledo; 2Alliance for Paired Donation, Perrysburg; 3Wake Forrest U, Winston Salem; 4Arbor Research, Ann Arbor

    Introduction: A non-profit kidney paired donation (KPD) organization undertook an Agency for Healthcare Research and Quality (AHRQ)-funded demonstration project to redesign reimbursement for the costs…
  • 2017 American Transplant Congress

    Simple Kidney Transplant Graft Survival (KTGS) Calculator Predicts 5- and 10-Year Allograft Survival.

    P. Sood,1 W. Cherikh,2 R. Mehta,1 A. Tevar,1 S. Hariharan.1

    1Transplant, University of Pittsburgh, Pittsburgh; 2Research Department, United Network for Organ Sharing, Richmond

    To develop a predictive 5- and 10-year Kidney Transplant Graft Survival (KTGS) calculator at the time of transplant for living donor (LD) and deceased (DD)…
  • 2017 American Transplant Congress

    Live Donor Liver Transplantation Using Grafts with More Than Two Bile Ducts – Does It Affect Patient Outcome?

    D. Kollmann, G. Sapisochin, N. Selzner, M. Cattral, P. Greig, L. Lilly, I. McGilvray, A. Ganekar, D. Grant, M. Selzner, N. Goldaracena.

    Multi Organ Transplant Program, Department of Surgery, Toronto General Hospital, Toronto, ON, Canada

    Introduction: It's been described that the use of live donor (LD) liver grafts with multiple bile ducts (BD) increases the risk of BD related complications…
  • 2017 American Transplant Congress

    Maximizing the Potential of Treg-Based Therapies for Transplant Rejection via Computational Immune-Modeling: Effect of Dose, Timing, and Distribution.

    G. Raimondi,1 A. Arun,1 O. Dorabiala,2 J. Arciero.3

    1Plastic & Reconstructive Surgery, Johns Hopkins University, Baltimore; 2Mathematics, Pennsylvania State University, Philadelphia; 3Mathematical Sciences, Indiana University-Purdue University Indianapolis, Indianapolis

    Purpose. Regulatory T cells (Treg), endogenous regulators of the immune system, have a significant therapeutic potential for prevention of transplant rejection. Experimental evidences however, indicate…
  • 2017 American Transplant Congress

    Similar Elevation of Gene Expression Associated with Antibody-Mediated Rejection (ABMR) of Renal Allografts Can Be Detected in Both Plasma Exosomes (pExo) and Biopsies (Bx) by Assessing mRNA Transcript Profiles.

    H. Zhang,1 C. Nast,2 J. Doldron,2 M. Cheung,2 J. Mirocha,3 J. Kahwaji,1 A. Vo,1 S. Jordan,1 M. Toyoda.1

    1Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles; 2Pathology, Cedars-Sinai Medical Center, Los Angeles; 3Biostatistics Center, Cedars-Sinai Medical Center, Los Angeles

    Background: ABMR is a major obstacle for successful transplant in HLA-sensitized patients (Pts). Prediction of ABMR by non-invasive diagnostic tools is desirable. Previously we showed…
  • 2017 American Transplant Congress

    Belatacept in Chronic Kidney Disease Stabilizes and Improves Renal Function in Pancreas Transplant Recipients: Intermediate Results.

    J. Chen, M. Mujtaba, T. Taber, M. Yaqub, J. Powelson, O. Adebiyi, J. Fridell, A. Sharfuddin.

    Indiana University Health, Indianapolis

    Background: We report our experience in converting Pancreas Transplant recipients from tacrolimus to Belatacept in order to avoid further worsening of kidney function.Results: Eight (7…
  • 2017 American Transplant Congress

    Non-Renal Factors Predicting Combined Liver-Kidney Transplantation for Non-Dialysis-Requiring Wait-Listed End Stage Liver Disease Patients: 14 Years of US Experience.

    A. Santos, M. Casey, K. Alquadan, J. Gregg, K. Womer.

    University of Florida, Gainesville, FL

    OBJECTIVE: We aimed to identify the non-renal factors associated with the higher likelihood of combined liver-kidney transplantation (CLKT) vs. liver transplantation alone (LTA) in end…
  • 2017 American Transplant Congress

    Lymphotoxin (LT) β Receptor-Mediated Non-Classical NFκB Signaling in Lymphatic Endothelial Eells (LEC) is Required for Homeostatic T Cell Migration.

    W. Piao, C. Brinkman, J. Bromberg.

    UMB, Baltimore

    Background: The selective recruitment of regulatory T cells (Treg) or blockade of memory/effector T cell migration to the graft and draining lymph nodes (dLN) are…
  • 2017 American Transplant Congress

    Graft-versus-Host Disease in Intestine Transplantation.

    J. Clouse, C. Kubal, B. Ekser, J. Fridell, R. Mangus.

    Surgery, Indiana University School of Medicine, Indianapolis, IN

    PurposeThis study reports the incidence, location, and outcomes of graft-versus-host disease (GVHD) at an active intestine transplant center. Subgroup analysis is employed to assess for…
  • 2017 American Transplant Congress

    CD4 Depletion Is Necessary and Sufficient for Long-Term Nonhuman Primate Xenotransplant Survival.

    S. Kim, L. Higginbotham, D. Mathews, C. Breeden, A. Stephenson, C. Larsen, M. Ford, J. Tector, A. Adams.

    Emory Transplant Center, Emory University, Atlanta, GA; University of Alabama Birmingham, Birmingham, AL

    Introduction. Xenotransplantation may alleviate the organ shortage, yet experimental renal xenotransplant has met limited success. We have previously reported the longest surviving pig-to-nonhuman primate (NHP)…
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