Am J Transplant, Volume 17, Suppl 3 Archives - Page 102 of 181 - ATC Abstracts

2017 American Transplant Congress
Assessment of the Association Between Measures of Metabolic Function and Pancreas Graft Survival.
S. Mittal,¹ R. Franklin,² J. Levy,² S. Gough,² E. Sharples,¹ P. Friend.¹
¹Department of Renal Transplantation, Oxford Transplant Centre, Oxford, United Kingdom; ²Department of Diabetology, Oxford Centre for Diabetes, Endocrinology and Metabolism, Oxford, United Kingdom
Introduction: The lack of a validated measure of graft function after pancreas implantation has hindered our ability to monitor recipients post-transplant and identify declines in…
2017 American Transplant Congress
TIM-3 – CEACAM1 Checkpoint Regulation of T-Cell Activation and Hepatocellular Function in Liver Transplantation.
K. Nakamura,¹ S. Kageyama,¹ M. Kujawski,³ R. Sosa,² E. Reed,² A. Zarrinpar,¹ R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Dept. Surgery, UCLA, Los Angeles, CA; ²Dept. Pathology, UCLA, Los Angeles, CA; ³Dept. Molecular Immunology, City of Hope, Duarte, CA
Background/Aim: We have documented crucial role of TIM-3 dependent T cell dysfunction in mouse orthotopic liver transplantation (OLT). CEACAM1 (CD66a; CM1; Carcinoembryonic Antigen-Related Cell Adhesion…
2017 American Transplant Congress
Successful Induction of Tolerance of Fully Allogeneic Lung Graft with Adenosine A_2A Receptor (A2AR) Agonist in MHC-Defined CLAWN Miniature Swine.
H. Sahara, M. Sekijima, T. Murokawa, Y. Ariyoshi, T. Iwanaga, Y. Ichinari, A. Shimizu, K. Yamada.
Center for Advanced Biomedical Science and Swine Research, Kagoshima University, Kagoshima, Japan
Introduction: A2AR agonist is known to potently attenuate lung ischemia-reperfusion injury. However, the long-term effects of A2AR agonist on lung allograft survival remain unclear especially…
2017 American Transplant Congress
Antibodies to Angiotensin Type II Receptor I Are Associated with Primary Graft Dysfunction After Orthotopic Heart Transplant in Patients with Ventricular Assist Device as Bridge to Transplant.
M. Hickey,¹ E. DePasquale,² S. Shah,³ D. Vucicevic,² J. Zhang,¹ N. Valenzuela,¹ M. Deng,² E. Reed.¹
¹UCLA Immunogenetics Center, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA; ²UCLA Division of Cardiology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA; ³UCLA David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA
Primary graft dysfunction (PGD) following orthotopic heart transplant (OHT) is one of the leading causes of posttransplant mortality. We hypothesized that antibody to angiotensin type…
2017 American Transplant Congress
Dementia and Alzheimer's Disease Among Older Kidney Transplant Recipients.
M. McAdams DeMarco, S. Bae, N. Chu, A. Gross, C. Brown IV, E. Oh, P. Rosenberg, K. Neufeld, R. Varadhan, M. Albert, J. Walston, D. Segev.
Johns Hopkins, Baltimore, MD
Background: Kidney transplantation (KT) is a growing treatment option for older ESRD patients. Older recipients may develop post-KT dementia and Alzheimer's disease (AD) associated with…
2017 American Transplant Congress
Increased Long-Term Mortality 20 years After Living Kidney Donation.
G. Mjoen,¹ S. Hallan,² H. Holdaas.¹
¹Dpt of Transplantation, Rikshospitalet, Oslo, Norway; ²Dpt of Nephrology, St. Olavs Hospital, Trondheim, Norway
Living kidney donors are healthy at the time of donation. Consequently, a long observation period is necessary to detect possible detrimental effects of donation. Most…
2017 American Transplant Congress
Increased Ischemic Inflammation Induces Recipient Endogenous Memory CD4 Cell-Graft Dendritic Cell Interactions to Provide Help for Activation of Endogenous Memory CD8 T Cells.
H. Tsuda, T. Tanaka, C. Su, A. Valujskikh, R. Fairchild.
Immunology, Cleveland Clinic, Cleveland, OH
Memory T cells provide protection against recurrent pathogens, but memory T cells with donor-reactivity pose a major barrier to successful allograft transplant and tolerance induction.…
2017 American Transplant Congress
Composite Prognostic Score Improves Clinical Benefit in Kidney Recipients Receiving Standard of Care Therapy for Antibody-Mediated Rejection.
D. Viglietti, A. Loupy, O. Aubert, E. Pillebout, C. Legendre, D. Glotz, C. Lefaucheur.
Paris Translational Research Center for Organ Transplantation, Paris, France
There is a marked heterogeneity in AMR patients' prognosis after SOC treatment including plasma exchange (PE) and intravenous immunoglobulins (IVIG). We investigated whether the use…
2017 American Transplant Congress
B Cell Deficiency Inhibits Both Antibody Mediated Rejection and T Cell Mediated Acute Rejection in a Rat Kidney Transplant Model.
S. Panzer, S. Reese, N. Wilson Schlei, B. Verhoven, D. Xiang, W. Zhong, A. Djamali.
University of Wisconsin, Madison, WI
Purpose: The specific role of B cells in the pathogenesis of acute rejection remains unclear.Methods: To address this question, we generated B cell deficient Lewis…
2017 American Transplant Congress
A Cost Comparison for Telehealth Utilization in the Kidney Transplant Waitlist Evaluation Process at a VA Center.
R. Forbes, D. Rybacki, T. Johnson, D. Shaffer, D. Hale.
Renal Transplantation, Tennessee Valley Healthcare System, U.S. Dept Veterans Affairs, Nashville
Background: The Department of Veterans Affairs (VA) has made efforts to improve access by increasing telehealth utilization. There have been limited publications on telehealth in…