ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Antibodies to Angiotensin Type II Receptor I Are Associated with Primary Graft Dysfunction After Orthotopic Heart Transplant in Patients with Ventricular Assist Device as Bridge to Transplant.

    M. Hickey,1 E. DePasquale,2 S. Shah,3 D. Vucicevic,2 J. Zhang,1 N. Valenzuela,1 M. Deng,2 E. Reed.1

    1UCLA Immunogenetics Center, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA; 2UCLA Division of Cardiology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA; 3UCLA David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA

    Primary graft dysfunction (PGD) following orthotopic heart transplant (OHT) is one of the leading causes of posttransplant mortality. We hypothesized that antibody to angiotensin type…
  • 2017 American Transplant Congress

    Dementia and Alzheimer's Disease Among Older Kidney Transplant Recipients.

    M. McAdams DeMarco, S. Bae, N. Chu, A. Gross, C. Brown IV, E. Oh, P. Rosenberg, K. Neufeld, R. Varadhan, M. Albert, J. Walston, D. Segev.

    Johns Hopkins, Baltimore, MD

    Background: Kidney transplantation (KT) is a growing treatment option for older ESRD patients. Older recipients may develop post-KT dementia and Alzheimer's disease (AD) associated with…
  • 2017 American Transplant Congress

    Post-Donation GFR Changes in Living Kidney Donors.

    E. Poggio,1 S. Arrigain,2 J. Augustine,1 S. Flechner,3 J. Schold.2

    1Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH; 2Qualitative Health Sciences, Cleveland Clinic, Cleveland, OH; 3Urology, Cleveland Clinic, Cleveland, OH

    Living kidney donor transplantation is the preferred treatment for ESRD because it confers excellent outcomes for recipients and poses reasonable risks to donors. Post-donation glomerular…
  • 2017 American Transplant Congress

    TIE'ing Statins to Microvascular Stability and Endothelial Cell Immunogenicity.

    C. Ghosh,1 A. Mak,1 M. McGourty,1 S. Parikh,2 X. Chen,2 S. Goldberg,1 J. Wedel,1 D. Briscoe.1

    1Transplant Research Program, Boston Children's Hospital, Boston, MA; 2Division of Nephrology, Beth Israel Deaconess Medical Center, Boston, MA

    Graft microvascular endothelial cells (EC) represent a critical interface between the recipient and the donor. Stable/quiescent EC support immunoregulation in part via the expression of…
  • 2017 American Transplant Congress

    Saftey & Long Term Outcomes of Tocilizumab (Anti-IL6R, TCZ) Therapy in Treatment of Chronic Antibody Mediated Rejection (CABMR) & Transplant Glomerulopathy (TG) in Highly-HLA Sensitized (HS) Patients (PTs).

    J. Choi,1 O. Aubert,2 A. Vo,1 A. Loupy,2 M. Haas,3 S. Louie,1 A. Kang,1 A. Peng,1 R. Najjar,1 E. Huang,1 M. Toyota,5 X. Zhang,4 S. Jordan.1

    1Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; 2Paris Transplant Group, University Paris Descartes, Paris, France; 3Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA; 4Department of HLA Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA; 5Transplant Immunology Lab, Cedars-Sinai Medical Center, Los Angeles, CA

    Introduction: DSAs in HS pts lead to poor allograft survival & return to a dialysis. Treatment options for CABMR and TG are limited. IL-6 appears…
  • 2017 American Transplant Congress

    B Cell Deficiency Inhibits Both Antibody Mediated Rejection and T Cell Mediated Acute Rejection in a Rat Kidney Transplant Model.

    S. Panzer, S. Reese, N. Wilson Schlei, B. Verhoven, D. Xiang, W. Zhong, A. Djamali.

    University of Wisconsin, Madison, WI

    Purpose: The specific role of B cells in the pathogenesis of acute rejection remains unclear.Methods: To address this question, we generated B cell deficient Lewis…
  • 2017 American Transplant Congress

    A Cost Comparison for Telehealth Utilization in the Kidney Transplant Waitlist Evaluation Process at a VA Center.

    R. Forbes, D. Rybacki, T. Johnson, D. Shaffer, D. Hale.

    Renal Transplantation, Tennessee Valley Healthcare System, U.S. Dept Veterans Affairs, Nashville

    Background: The Department of Veterans Affairs (VA) has made efforts to improve access by increasing telehealth utilization. There have been limited publications on telehealth in…
  • 2017 American Transplant Congress

    Adoptive Immunotherapy with Liver Allograft-Derived Lymphocytes Compensate for the Susceptibility to Post-Liver Transplant Blood Stream Infection Associated with FCGR3A SNP.

    H. Ohdan, M. Ohira, S. Shimizu, Y. Tanaka, H. Tahara, K. Ide, K. Ishiyama, T. Kobayashi.

    Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan

    By studying the single nucleotide polymorphisms (SNPs) of FCGR2A and FCGR3A, genes encoding FcγR, we previously demonstrated the significantly higher incidence of blood stream infections…
  • 2017 American Transplant Congress

    Kidney Transplant Recipient Intermediate and Long Term Outcomes for Living Donor Gifted Lithiasis.

    S. Doshi, M. Yaqub, T. Taber, M. Mujtaba, D. Mishler, O. Adebiyi, C. Sundaram, J. Powelson, A. Sharfuddin.

    Indiana University Health, Indianapolis

    BACKGROUND: Nephrolithiasis is considered at least a relative contraindication to living donor nephrectomy due to the potential for adverse outcomes of recurrence, obstruction and infection.…
  • 2017 American Transplant Congress

    ABO-Incompatibility Using Ritiuximab Does Not Increase Hepatocellular Carcinoma Recurrence After Liver Transplantation.

    J. Kim, S. Kim, J. Lee, K.-S. Kim, J. Lee, G.-S. Choi, J. Park, C. Kwon, J.-W. Joh, S.-K. Lee.

    Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

    Background and aims: ABO-incompatible (ABO-I) living donor liver transplantation (LDLT) has a high success rate. However, a difference in hepatocellular carcinoma (HCC) recurrence rates has…
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