2017 American Transplant Congress
Allograft Crescent Predicts Graft Failure in Recurrent IgA Nephropathy Patients.
Seoul National University Hospital, Seoul, Korea
Background A recent multicenter study demonstrates predictive value of crescents in native IgA nephropathy (IgAN), however it remains unclear whether allograft crescent is associated with…2017 American Transplant Congress
The New Kidney Allocation System: The Effect on Elderly Transplantation in the US. Review of UNOS Database.
Surgery, State University New York, Syracuse, NY
The New Kidney Allocation System(KAS) improve access disadvantaged groups. The effect on the elderly population, recipients >=65 is unknown.Methods: Retrospective analysis of UNOS database preKAS…2017 American Transplant Congress
A Novel KPD Mechanism to Increase Transplants When Some Candidates Have Multiple Willing Donors.
1Carnegie Mellon U, Pittsburgh; 2U of Maryland, College Park; 3UNOS, Richmond; 4Yale U, New Haven
Purpose: Current kidney exchanges such as the OPTN Kidney Paired Donation (KPD) program allow candidates to list multiple willing donors, but only one will donate…2017 American Transplant Congress
B Cell-Derived Cytokines Rather Than T/B Cognate Interactions Mediate CD8 T Cell Reconstitution Following Lymphoablation.
Immunology, Cleveland Clinic, Cleveland, OH
Antibody-mediated lymphoablation is a commonly used induction therapy in sensitized transplant recipients. Using murine anti-thymocyte globulin (mATG) in a model of BALB/c (H-2d) to B6…2017 American Transplant Congress
Efficacy and Safety of ASP0113 versus Placebo in CMV-Seronegative Kidney Transplant Patients Receiving an Organ from a CMV-Seropositive Donor.
Introduction: ASP0113 is a first-in-class DNA-based vaccine in development for the prevention of human cytomegalovirus (CMV) infection in at-risk hematopoietic cell transplant and solid organ…2017 American Transplant Congress
CD16a-Activated NK Cells in ABMR Are Highly Similar to CD3-Activated Effector T Cells in TCMR.
University of Alberta, Edmonton, Canada
BACKGROUND: NK cell CD16a and T cell CD3 activate shared pathways. Since NK cell CD16a activation occurs in antibody-mediated rejection (ABMR) and T cell CD3…2017 American Transplant Congress
Inflammatory Cytokines Are Associated with Angiotensin II Type 1 Receptor Antibodies and Vascular Inflammation in Pediatric Renal Transplantation.
1University of California, Los Angeles, CA; 2Duke University, Durham, NC
Background: We recently found that angiotensin II type 1 receptor antibody (AT1R-Ab) was associated with decreased renal function in pediatric renal transplant recipients independent of…2017 American Transplant Congress
Predicting Immunologic Risk for Acute Rejection in Pediatric Liver Transplantation.
Yale University, New Haven, CT
Background: Studies in heart, lung, kidney, & liver transplantation (LT) indicate an increased negative impact of antibodies (Ab) to HLA on allograft outcome.Aim: To describe…2017 American Transplant Congress
Educational Strategies for Increased Wait-Listing Rates: Opportunities for Dialysis Center Intervention.
1UCLA, Los Angeles, CA; 2SLU, St. Louis, MO
Dialysis centers vary in how well they educate patients about kidney transplant (KT). This study categorized common groups of educational strategies used by dialysis staff;…2017 American Transplant Congress
Characterization of Human Plasma Cell Proteasome Adaptations to Proteasome Inhibitor Therapy: A Precision Medicine Approach to Overcome Drug Resistance in Desensitization.
1U of Cincinnati, Cincinnati, OH; 2Cincinnati Children's, Cincinnati, OH
Purpose: Bone marrow niche-resident plasma cells (BMNRPCs) exhibit variable sensitivity to proteasome inhibitor (PI) therapy. Here, we characterized alterations in the gene and protein expression…
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